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Treating eperythrozoonosis medicine, preparing method and uses thereof

A technology for porcine epierythrocytes and bodily diseases, applied in antibacterial drugs, medical formulas, plant raw materials, etc., can solve the problems of pork poisonous arsenic residues, endangering consumers' health, polluting the environment, etc., to solve the problem of drug residues and low cost , The effect of simple preparation method

Inactive Publication Date: 2008-07-23
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some even use arsenic preparations for treatment. Although it has a certain effect, it pollutes the environment, and the toxic arsenic residue in pork endangers the health of consumers.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] 1) Preparation of ZTC clarifier Type III (purchased from Tianjin Zhengtiancheng Clarification Technology Co., Ltd.)

[0015] Preparation of ZTC clarifier Type III A solution: Dissolve 5g of component A in 20ml of deionized water (distilled water) and stir into a paste, then add 480ml of deionized water, swell for 24 hours, stir to obtain 500ml of 1% A solution.

[0016] Preparation of ZTC clarifier type III B solution: Dissolve 5g of component B in 20ml of 1% acetic acid and stir into a paste, add 480ml of 1% acetic acid, swell for 24 hours, stir to obtain 500ml of 1% B solution.

[0017] 2) Put 600g of Artemisia camel, 200g of astragalus, and 200g of licorice in a stainless steel bucket, add 8000ml of deionized water, boil, after boiling, continue to boil for 1 hour, pour out the liquid medicine; add 6000ml of deionized water, continue to fry After boiling, continue to decoct for 1 hour, pour out the medicinal liquid, and combine the medicinal liquid decocted twice. A...

experiment example

[0022] Pharmacological experiment

[0023] 1. In vitro shedding experiment of traditional Chinese medicine on porcine eperythrocytic bodies

[0024] in vitro susceptibility test

[0025] 1. Add 1 drop of pig blood suspension infected with Eperythrozoonosis on 4 glass slides respectively; then add the following liquids respectively: 0.05g / L Xuechongjing, 0.05g / L Oxytetracycline Hydrochloride Injection 1.0 g / L of traditional Chinese medicine solution and 1 drop of normal saline (blank control group); mix well and observe under a high-power microscope immediately.

[0026] judgement standard:

[0027] Eperythrozoon detached from the surface of red blood cells and Eperythrozoon in the plasma stopped shaking, it was judged as drug sensitive.

[0028] Drug susceptibility test results

[0029] 1. After 2 minutes, Xuechongjing will make the epierythrosomes fall off from the red blood cells, and after 3 minutes, the epierythrosomes in the plasma will stop swinging;

[0030] 2. Oxy...

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PUM

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Abstract

The invention discloses a drug combination for curing pig eperythrozoonosis and a preparation method and the application thereof. The invention is made from peganum nigellastrum bge and glycyrrhiza medicine; the preparation method comprises the steps of decocting, removing impurity by clarifier, so as to obtain clarifying, transparent and red-brown liquid. The invention is applied to treatment of pig eperythrozoonosis with distinctive effect, avoiding chemical drug and arsenic preparation used in curing pig eperythrozoonosis, solving the environment pollution problem caused by curing the disease and avoiding the residues problem of toxic arsenic in animal food as well.

Description

technical field [0001] The invention relates to a composition for treating porcine eperythrozoonosis, a preparation method and application thereof. Background technique [0002] Eperythrozoonosis is a zoonotic infectious disease caused by Eperythrozoon infection. Eperythrozoon is a kind of microorganism that parasitizes on the surface of red blood cells, plasma and bone marrow. Pigs are usually more prone to Eperythrozoonosis, which is an acute, febrile infectious disease caused by Eperythrozoon attached to the surface of pig red blood cells or dissociated in the plasma, which occurs in many countries and regions and popular. Clinically, the disease is characterized by fever, anemia, hemolytic jaundice, dyspnea, redness of the skin, etc., resulting in immunosuppression of the animal body, reproductive impairment, and low birth survival rate. In recent years, it has become an explosive epidemic in most provinces and regions in China, causing serious economic losses to the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61P31/04
Inventor 苗小楼王玲牛建荣李宏胜
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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