Applications of human growth hormone and human epidermal growth factor combination in beauty treatment

Abstract

The invention discloses the use of a composition comprising human growth hormone and human epidermal growth factor in cosmetics and provides a production process thereof. The invention uses human growth hormone in cosmetics together with human epidermal growth factor by using biotechnology. The human growth hormone and the human epidermal growth factor has synergistic effects in supplementing bioactive factors for promoting epidermal cell metabolism and proliferation, thereby basically improving the physiological status of skin, promoting repairing and metabolism of epidermal tissues, promoting extracellular synthesis of biomacromolecules such as hyaluronic acid and glycoprotein, promoting skin tendering and rejuvenation, relieving color spots, reducing wrinkles, and resisting aging. The inventive composition has remarkably cosmetic effect and has the advantages of good safety and reliability, and no adverse side effects.

Description

technical field [0001] The invention relates to the application of the human growth hormone and human epidermal growth factor composition in beauty treatment, and also provides its production process, which belongs to the technical field of biological beauty products. Background technique [0002] Human Epidermal Growth Factor (Human Epidermal Growth Factor, hereinafter referred to as: hEGF), is an important growth factor secreted by the human body, and is a short-chain polypeptide with a relative molecular weight of 6222 composed of 53 amino acids. As a powerful cell division factor, hEGF has high biological activity. A very small amount of hEGF can strongly promote the division and growth of skin cells, and can also stimulate the synthesis and secretion of some extracellular macromolecules (such as hyaluronic acid and glycoproteins, etc.), which has a strong role in promoting the growth and metabolism of the epidermis. The skin is delicate and smooth, and the cosmetic eff...

AI Technical Summary

Problems solved by technology

Therefore, its production, transportation, and preservation have become insurmountable gaps, thus hindering its practical application.

[0006] (2) hEGF is easily degraded by protease and loses its activity

[0007] (3) hEGF is difficult to absorb through the skin

[0011] (1) It is difficult for hGH to maintain its biological activity at room temperature

After being placed at room temperature for a short period of time, it loses its biological activity, so its production, transportation, and storage have become an insurmountable gap, making it difficult to achieve practical applications

[0012] (2) hGH is easily degraded by protease and loses its activity

[0013] (3) hEGF is difficult to absorb through the skin

[0014] At present, the combination of hGH or hEGF and hGH has not been reported in the literature.

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