Nano memory alloy intrauterine device

Abstract

The invention relates to a female intrauterine contraception apparatus, in particular to a nanometer memory alloy intrauterine contraception device which comprises a memory alloy stent and a composite material body which is connected with the stent. An anal filament can be provided or not. The female intrauterine contraception apparatus is characterized in that the composite material body is compounded and manufactured by contraception activity materials and polymer materials. The contraception activity materials comprise at least one of nanometer copper oxide particles and micron copper oxide particles. The intrauterine contraception device of the invention has the advantages of low abscission rate, high contraception rate, long-term usage, small stimulation on endometrium, insignificant side effects and high usage of the copper, which can equably and steadily release copper ions, is suitable for relatively anoxic environment of uterus and can be placed in a conveyor for long time, etc. In addition, the female intrauterine contraception apparatus has unexpected effect that the composite materials help the memory alloy stent to prevent the abscission, so that the abscission rate of the intrauterine contraception device of the invention is lower.

Description

Technical field [0001] The invention relates to an intrauterine contraceptive device for women, in particular to a nano-memory alloy intrauterine contraceptive device. Background technique [0002] Intrauterine device (IUD) is a contraceptive device placed in a woman's uterine cavity. It is a reversible and long-acting contraceptive device. It is currently a contraceptive method widely used by women of childbearing age in my country. There are more than a dozen common types in clinical practice, such as copper-containing T-type, uterine cavity-type, O-type, fixed type, etc.; copper-containing and indomethacin-containing drugs include Yuangong-type, γ-type, etc.; and progesterone-containing drugs With Mirena, these contraceptive devices use active contraceptive substances to prevent implantation of fertilized eggs, thereby achieving the purpose of contraception. [0003] The types of IUD can be roughly divided into two categories: inert IUD and active IUD. Inert IUD does not conta...

AI Technical Summary

Problems solved by technology

[0005] 1. The contraceptive effect of copper increases with the increase of the surface area of ​​copper, but the surface area increases, and the side effects of the device increase accordingly, bleeding and pain will occur;

[0006] 2. In the early stage of IUD implantation in the uterus, Cu 2+ Explosive release phenomenon, severe side effects such as pain and bleeding;

[0007] 3. The corrosion process of bare copper is very complicated and is greatly affected by the environment of the uterine cavity. However, the individual differences of the uterus are great, and the individual differences are also great at different times. It is difficult to obtain an accurate corrosion curve. Therefore, Cu 2+ The release rate is difficult to control;

[0008] 4. The effective utilization rate of copper is very low. Even in the case of complete corrosion, Cu that finally enters the uterine cavity fluid to play a contraceptive effect 2+ It also only accounts for about 1 / 3 of the total Cu corrosion, and there is CaCO on the copper surface 3 and other deposition, aggravating the stimulation of the IUD to the endometrium;

[0009] 5. Most IUDs use polyethylene or stainless steel stents. Taking polyethylene stents as an example, it is difficult to completely restore the original shape after being placed in the conveyor and then sent into the uterine cavity. The time in the conveyor should not exceed 3 minutes. Due to poor deformation ability, these IUDs are easy to fall off and the process of taking the device is very difficult;

[0010] 6. IUD seldom satisfies the existence of copper in the palace corners, palace fundus and palace body in terms of shape design, so Cu 2+ Uneven distribution in the uterine cavity

[0011] At present, there is no copper-containing IUD that can solve all the above-mentioned shortcomings at the same time

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