Kit for evaluating medicine of glonoin

A technology of nitroglycerin and a kit, which is applied in the fields of molecular biology and medicine, and can solve problems such as inability to produce nitric oxide, difficulty in effectively functioning, and influence on esterase activity.
CN101363801AInactive Publication Date: 2009-02-11XINBAXIANG SHANGHAI MOLECULAR MEDICAL TECH SHANGHAI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
XINBAXIANG SHANGHAI MOLECULAR MEDICAL TECH SHANGHAI
Publication Date
2009-02-11
Estimated Expiration
Not applicable · inactive patent
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Abstract

The invention discloses a kit for detecting the sensibility of an individual to glonoine medicines. The kit comprises specific primer pair for detecting SNP polymorphism genotype rs671 on ALDH2 gene, a specific fluorescent probe pair and a routine component used for fluorescent quantitative PCR detection. The sensibility of the individual to the glonoine medicines is analyzed and evaluated by detecting the genotype of SNP locus rs671on the ALDH2 gene.
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Description

technical field

[0001] The invention relates to the fields of molecular biology and medicine, and more specifically, the invention relates to a kit for detecting the drug sensitivity of an individual to nitroglycerin. Background technique

[0002] Nitroglycerin (GTN, glyceryl trinitrate, nitroglycerin) has been used in the treatment of angina pectoris and heart failure for 130 years. Sublingual nitroglycerin tablets are the routine first-choice prescription for anti-angina pectoris acute attack of coronary heart disease, but its clinical effectiveness is often due to It varies from person to person. Some people saved their lives in time because of it, but after some people took it, the effect was not very obvious. In the past, the domestic and foreign medical circles have always believed that the poor curative effect of nitroglycerin on some patients is caused by its "drug resistance", but the research results prove that this is not the case. Recent studies have shown that...

Claims

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