Compositions comprising kakadu plum extract or acai berry extract

A technology of kakadu plum and composition, which is applied in the field of composition to improve the visual appearance of the skin, and can solve problems such as skin irritation, chronic skin damage, and skin toxicity

Active Publication Date: 2009-02-18
MARY KAY INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Several of the aforementioned methods have been shown to have various drawbacks such as significant skin irritation or skin toxicity
Moreover, most of these approaches involve chronic damage to the skin utilizing mechanisms to initiate repair

Method used

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  • Compositions comprising kakadu plum extract or acai berry extract
  • Compositions comprising kakadu plum extract or acai berry extract
  • Compositions comprising kakadu plum extract or acai berry extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0096] Example 1 Composition Containing Kakadu Plum Extract

[0097] Non-limiting examples of the present invention containing kakadu plum extract are described in Tables 1 and 2.

[0098] Table 1 ＊

[0099] Element % concentration (by weight) Phase A water 84.44 xanthan gum 0.1 Methylparaben 0.15 Propylparaben 0.1 citric acid 0.01 Phase B cetyl alcohol 4.0 Glyceryl Stearate+PEG 100 4.0 Octyl palmitate 4.0 Dimethicone 1.0 tocopheryl acetate 0.2 Phase C Kakadu Plum Extract 2.0

[0100] * Sprinkle the xanthan gum in the water and mix for 10 minutes. Then add all ingredients of Phase A and heat to 70-75°C. Add all of Phase B to a separate beaker and heat to 70-75°C. Mix Phase A and Phase B at 70-75°C. Continue mixing and allow the composition to cool to 30°C. Subsequently, the ingredients of Phase C were added while mixing.

[0101] Table 2 ＊

[0102] Elemen...

Embodiment 2

[0105] Example 2 Biological Efficacy of Kakadu Plum Extract as Antioxidant

[0106] The ability of kakadu plum extract as an antioxidant was investigated in terms of its ability to (1) reduce existing internal oxidation in cells; and (2) reduce damage to cells from external oxidation. commented.

[0107] Peroxide analysis: Cell peroxide was measured by flow cytometry using a peroxide-specific dye, 2',7'-dichlorofluorescein diacetate (DCFH-DA). Initially non-fluorescent, DCFH-DA is rapidly concentrated in living cells by an enzyme-dependent process. After modification by the cell's peroxide, the dye exhibits strong green fluorescence when excited by laser light. Basal peroxide production, produced by normal cellular metabolic mechanisms, will induce the gradual formation of low levels of peroxide-specific cellular fluorescence. In this way, the measurement of this fluorescence without any treatment can be used as a negative control for comparison purposes. Moreover, extrace...

Embodiment 3

[0109] Example 3 Collagen Production in Human Dermal Fibroblasts in the Presence of Kakadu Plum Extract

[0110] The ability of kakadu plum extract to increase collagen production in human dermal fibroblasts was investigated.

[0111] Collagen Production Protocol: Normal human dermal fibroblast (NHDF) cells from frozen vials were grown to semi-confluency in tissue culture flasks (T25 flasks). Two confluent T25 flask cultures were trypsinized, washed, resuspended to 16 ml and inoculated as much as possible into 96-well plates (200 μl / well) (columns 4-12 only). Cells were allowed to grow overnight or until cells reached 100% confluency. After reaching confluency, the spent medium was aspirated and 200 [mu]l of fresh medium with or without the sample of interest was added (three replicates). figure 2 The liquid extract in was 1.0% (20 μl of 100X stock solution) and 0.1% (2 μl of 100X stock solution) of Kakadu plum extract and diluted into a final volume of 200 μl of NHDF growt...

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Abstract

A topical skin care composition comprising kakadu plum extract or acai berry extract, or a combination of both, is disclosed. The composition can include a high oxygen radical absorbance capacity (ORAC) value. The composition can improve the skin's visual appearance, physiological functions, clinical properties, and / or biophysical properties.

Description

[0001] Cross References to Related Applications [0002] This application claims U.S. Provisional Patent Serial No. 60 / 760,103, filed January 19, 2006, U.S. Provisional Patent Serial No. 60 / 760,977, filed January 20, 2006, and U.S. Provisional Patent Serial No., filed January 20, 2006 60 / 760,979 entitlements. The contents of these applications are incorporated herein by reference. technical field [0003] The present invention relates to compositions that can be used to improve the visual appearance of the skin. In particular, the present invention relates to topical skin care compositions comprising extracts of kakadu plum (Terminalia ferdinandiana) and / or extracts of acai berry (Euterpe oleracea). Background technique [0004] With aging, chronic exposure to adverse environmental factors or malnutrition, the visual appearance, physical properties and physiological functions of the skin may change in ways that are considered visually undesirable. The most pronounced and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/74
Inventor 大卫·甘M·海因斯贾维尔·阿拉维那布莱恩·琼斯
Owner MARY KAY INC
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