Pharmaceutical composition for repairing testicular senescense and damnification, and enhancing function of male

A composition and drug technology, applied in the direction of drug combination, drug delivery, disease, etc., can solve problems such as inappropriateness, polycythemia, etc.

Inactive Publication Date: 2009-04-15
GUANGDONG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, no suitable treatment method has been found for the testicular damage caused by aging and the decrease of male sexual function, and there is no suitable treatment drug. Supplementing testosterone is the only way to treat the decrease of male sexual function at present. Other androgens cannot replace testost

Method used

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  • Pharmaceutical composition for repairing testicular senescense and damnification, and enhancing function of male
  • Pharmaceutical composition for repairing testicular senescense and damnification, and enhancing function of male

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Experimental program
Comparison scheme
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Embodiment 1

[0015] 1 material

[0016] 1.1 Experimental animals

[0017] A total of 33 3-month-old male SD rats with SPF grade were selected in this study, weighing (208±28) g. Provided by the Guangdong Provincial Laboratory Animal Center, Guangdong Provincial Laboratory Animal Certificate Number: Yuejian Zhengzi 2006A015, Beijing-born rats were fed with full-price feed during the maintenance period, and they had free access to food and water.

[0018] 1.2 Experimental drugs and reagents

[0019] 1.2.1 Experimental drugs

[0020] Preparation of Epimedium ginseng silk water extract (sheep ginseng oral liquid): according to the method proposed in the patent process (1) of the present invention, get 1 kg of Epimedium and 1 kilogram of ginseng silk, pulverize them respectively, and then use Bailey micro-powder machine Perform micronization, decoct with water for 3 times, each time for 2 hours, filter, combine the three filtrates, concentrate to 100% (1g crude drug / ml) concentration, and pr...

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Abstract

The invention relates to a medical composition for repairing testicular senescense and injury and strengthening the male function. The medical composition is a compound preparation which consists of Chinese medicines of epimedium and ginseng fiber. As proved by research, the compound preparation has good function in preventing D-galactose subacute senile mouse testis injury, and can improve the SOD activity of testis, reduce the MDA content and improve the oxidation resistance capability of the whole organism, maintain the balance of metabolism of free radicals and reduce lipid peroxidation, so as to effectively inhibit apoptosis of testicular cells induced by cellular oxidation, obviously improve or adjust metabolism of senile cells, and delay the aging process. The preparation can be taken as health food and medicine, and is used for preventing male senescence, repairing testicular senescense and injury and strengthening the male function.

Description

technical field [0001] The invention relates to a pharmaceutical composition for repairing testicular aging damage and enhancing male function. The pharmaceutical composition is a compound preparation composed of traditional Chinese medicine Epimedium and Radix Ginseng. Studies have shown that the compound preparation has a good effect on senile testicular damage. Preventive and therapeutic effects can enhance male function and delay aging. Background technique [0002] With the gradual improvement of living and sanitary conditions and the continuous extension of human life expectancy, diseases associated with aging have become a common problem faced by the world. Human aging is closely related to the degeneration of gonad structure and function. From the age of 50, male testicular tissue can undergo degenerative changes, and then further structural atrophy and functional degeneration can occur. With aging, the physiological functions of the testicles of middle-aged and eld...

Claims

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Application Information

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IPC IPC(8): A61K36/296A61K9/00A61K9/14A61K9/16A61K9/48A61P15/08
Inventor 吴铁崔燎李彬张益嘉张新乐吴光粱戴娟秀林坚涛
Owner GUANGDONG MEDICAL UNIV
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