Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composition comprising at least one c-glycoside derivative and at least one hyaluronic acid and its cosmetic use

A technology of glycoside derivatives, hyaluronic acid, applied in the field of skin care and/or its accessories, which can solve problems such as enhancing skin barrier function

Inactive Publication Date: 2009-07-15
LOREAL SA
View PDF14 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0038] However, these derivatives have hitherto never been used to improve and / or enhance skin barrier function, let alone in combination with hyaluronic acid

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition comprising at least one c-glycoside derivative and at least one hyaluronic acid and its cosmetic use
  • Composition comprising at least one c-glycoside derivative and at least one hyaluronic acid and its cosmetic use
  • Composition comprising at least one c-glycoside derivative and at least one hyaluronic acid and its cosmetic use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0481] Example 1: Tests performed: Analysis of keratinocyte transglutaminase (TGk) activity

[0482] Study of the in vitro effect of two active agents on keratinocyte differentiation (C-β-D-xylopyranoside-2-hydroxypropane with 30% by weight of active substance in a 60 / 40 water / 1,2-propanediol mixture , and hyaluronic acid). For this purpose, normal human epidermal keratinocytes pretreated with mitomycin to prevent their proliferation in starved medium consisting of 40% depleted SFM medium and 60% Earl BufferSalt Sodium (EBSS) buffer (NHEK) in culture medium. The thus slowed metabolism of these cells - their ability to differentiate - is then quantified by analyzing the keratinocyte transglutaminase (TGk) activity of NHEK pretreated with active agents using standard radiochemical assays.

[0483] Calcium Chloride (CaCl 2 ) - a molecule known to stimulate keratinocyte differentiation was used as a reference molecule for this analysis.

[0484] operating procedures

[0485] ...

Embodiment 2

[0504] Example 2: Examples of Formulations

[0505] The content is expressed as mass percentage content.

[0506] Compositions A and B are H / E emulsions gelled with carbomer and / or ammonium polyacryloyldimethyltaurate and prepared according to conventional techniques. Composition B is very highly organosiliconated. Composition C is a highly organosiliconated E / H emulsion prepared according to conventional techniques. Composition D is a clear gel with a high concentration of hyaluronic acid gelled with ammonium polyacryloyldimethyltaurate.

[0507] A B C D magnesium sulfate 0.70 sodium hydroxide 0.08 Triethanolamine 1.23 0.01 0.02 Hydroxyethylpiperazineethanesulfonic acid 1.00 1.00 C-β-D-xylopyranoside-2-hydroxypropane (1) 1.00 1.00 1.00 1.00 algae extract 1.00 0.20 0.20 0.20 Distearyldimethylamine hectorite 0.20 silica 2.00 3.00 Acrylate Copolymer 0.30 Tris...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
molecular weightaaaaaaaaaa
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
Login to View More

Abstract

The present invention relates to a topical cosmetic and / or dermatological composition comprising, in a physiologically acceptable medium, at least one hyaluronic acid or a derivative thereof and at least one C-glycoside derivative.

Description

technical field [0001] The invention relates to the field of care of the skin and / or its annexes. [0002] A subject of the present invention is a topical dermatological and / or cosmetic composition comprising at least one hyaluronic acid or derivative thereof and at least one C-glycoside derivative in a physiologically acceptable medium. [0003] The invention also relates to a cosmetic therapy of the skin and / or its appendages for improving the barrier function, comprising at least one step of applying to the skin at least one composition as defined above. [0004] In particular, the compositions of the present invention are used to improve the barrier function of the skin. It is thus useful for hydration of the skin, improving skin suppleness, improving and / or reducing skin micro-relief, and combating signs of skin aging. Background technique [0005] Human skin is composed of two compartments, a deep part (dermis) and a superficial part (epidermis). [0006] The dermis...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/60A61Q19/00A61Q19/08
Inventor L·比塞J·拉布罗J·塞内S·索赛
Owner LOREAL SA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com