Traditional Chinese medicine composition and preparation method and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition and a preparation method and the application thereof. The traditional Chinese medicine composition is prepared from eucommia bark, radix scutellariae (preparation), herba artemisiae capillaries, capejasmine (stir-bake), rhubarb, herba hyperici japonica, dittany bark, Tuckahoe, salvia miltiorrhiza and radix curcumae according to certain proportioning by weight and can be prepared to any common peroral dosage type. The traditional Chinese medicine composition has the action of kidney tonify, miscarriage prevention, petechia passing, cholagogic effect, invigorating spleen and eliminating dampness and is safe and effective to treat pregnancy intrahepatic cholestasis, ABO blood group incompatibility, icterus neonatorum, and thelike.

Description

technical field

[0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and in particular relates to a traditional Chinese medicine composition and a preparation method and application thereof. Background technique

[0002] Intrahepatic cholestasis of pregnancy (IPC) is a disease that occurs in the second and third trimesters of pregnancy, is characterized by itching and jaundice, and is accompanied by varying degrees of liver damage. It has a tendency to recur in subsequent pregnancy. It is one of the clinically difficult and high-risk diseases in obstetrics and gynecology. 1. It can lead to miscarriage, premature delivery, premature rupture of membranes, fetal distress, stillbirth, postpartum hemorrhage, etc., which seriously endanger the health of perinatal infants. This disease is a high-risk pregnancy, and its etiology and pathogenesis are not clear yet. There is no recognized specific treatment drug.

[0003] After many years of clinical ex...

Examples

Embodiment 1

[0114] Embodiment 1 (10 grams per weight part)

[0115] The preparation of pharmaceutical composition mixture of the present invention

[0116] Eucommia 400g Scutellaria baicalensis (made) 60g Capillary 300g

[0117] Shanzhi (stir-fried) 100g Rhubarb 30g Tianjihuang 300g

[0118] White fresh skin 200g Poria cocos 200g Salvia miltiorrhiza 150g

[0119] Turmeric 60g

[0120] The above ten flavors are soaked in water for 1 hour and then decocted twice. For the first time, add water 10 times the total weight of the original medicinal materials, and for the second time add water 8 times the total weight of the original medicinal materials. After each boiling, continue decocting for 1 hour, filter Take the filtrate, discard the residue, combine the secondary medicinal liquid, and after standing for 24 hours, take the supernatant and concentrate it to 1000 milliliters (each milliliter contains 1.8 grams of crude drug), after standing for 24 hours, filter the supernatant, add water...

Embodiment 2

[0121] Embodiment 2 (this example every weight portion 10 grams)

[0122] The preparation of pharmaceutical composition mixture of the present invention

[0123] Eucommia 350g Scutellaria baicalensis (manufactured) 50g Capillary wormwood 200g

[0124] Shanzhi (stir-fried) 60g rhubarb 50g Tianjihuang 250g

[0125] White fresh skin 150g Poria cocos 150g Salvia miltiorrhiza 100g

[0126] Turmeric 100g

[0127] The above ten flavors are soaked in water for 2 hours and then decocted twice. For the first time, add water 10 times the total weight of the original medicinal materials, and for the second time add water 8 times the total weight of the original medicinal materials. After each boiling, continue to decoct for 1 hour. Filter the filtrate, discard the residue, combine the secondary medicinal liquid, and after standing for 24 hours, take the supernatant and concentrate it to 1000 ml (1.46 grams of crude drug per ml), after standing for 24 hours, filter the supernatant, add ...

Embodiment 3

[0128] Embodiment 3 (this example every weight portion 10 grams)

[0129] The preparation of pharmaceutical composition mixture of the present invention

[0130] Eucommia 450g Scutellaria baicalensis (manufactured) 100g Capillary 350g

[0131] Shanzhi (stir-fried) 150g Rhubarb 25g Tianjihuang 400g

[0132] White fresh skin 300g Poria cocos 250g Salvia miltiorrhiza 200g

[0133] Turmeric 50g

[0134] The above ten flavors are soaked in water for 1 hour and then decocted 3 times. For the first time, add water 10 times the total weight of the original medicinal materials, and for the second time add water 8 times the total weight of the original medicinal materials. After each boiling, continue decocting for 1 hour, filter Take the filtrate, discard the dregs, combine the three medicinal liquids, and after standing for 24 hours, take the supernatant and concentrate to 1000 ml (each ml contains 2.27 grams of crude drug), after standing for 24 hours, filter the supernatant, and ...

technical field

[0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and in particular relates to a traditional Chinese medicine composition and a preparation method and application thereof. Background technique

[0002] Intrahepatic cholestasis of pregnancy (IPC) is a disease that occurs in the second and third trimesters of pregnancy, is characterized by itching and jaundice, and is accompanied by varying degrees of liver damage. It has a tendency to recur in subsequent pregnancy. It is one of the clinically difficult and high-risk diseases in obstetrics and gynecology. 1. It can lead to miscarriage, premature delivery, premature rupture of membranes, fetal distress, stillbirth, postpartum hemorrhage, etc., which seriously endanger the health of perinatal infants. This disease is a high-risk pregnancy, and its etiology and pathogenesis are not clear yet. There is no recognized specific treatment drug.

[0003] After many years of clinical ex...

Examples

Embodiment 1

[0114] Embodiment 1 (10 grams per weight part)

[0115] The preparation of pharmaceutical composition mixture of the present invention

[0116] Eucommia 400g Scutellaria baicalensis (made) 60g Capillary 300g

[0117] Shanzhi (stir-fried) 100g Rhubarb 30g Tianjihuang 300g

[0118] White fresh skin 200g Poria cocos 200g Salvia miltiorrhiza 150g

[0119] Turmeric 60g

[0120] The above ten flavors are soaked in water for 1 hour and then decocted twice. For the first time, add water 10 times the total weight of the original medicinal materials, and for the second time add water 8 times the total weight of the original medicinal materials. After each boiling, continue decocting for 1 hour, filter Take the filtrate, discard the residue, combine the secondary medicinal liquid, and after standing for 24 hours, take the supernatant and concentrate it to 1000 milliliters (each milliliter contains 1.8 grams of crude drug), after standing for 24 hours, filter the supernatant, add water...

Embodiment 2

[0121] Embodiment 2 (this example every weight portion 10 grams)

[0122] The preparation of pharmaceutical composition mixture of the present invention

[0123] Eucommia 350g Scutellaria baicalensis (manufactured) 50g Capillary wormwood 200g

[0124] Shanzhi (stir-fried) 60g rhubarb 50g Tianjihuang 250g

[0125] White fresh skin 150g Poria cocos 150g Salvia miltiorrhiza 100g

[0126] Turmeric 100g

[0127] The above ten flavors are soaked in water for 2 hours and then decocted twice. For the first time, add water 10 times the total weight of the original medicinal materials, and for the second time add water 8 times the total weight of the original medicinal materials. After each boiling, continue to decoct for 1 hour. Filter the filtrate, discard the residue, combine the secondary medicinal liquid, and after standing for 24 hours, take the supernatant and concentrate it to 1000 ml (1.46 grams of crude drug per ml), after standing for 24 hours, filter the supernatant, add ...

Embodiment 3

[0128] Embodiment 3 (this example every weight portion 10 grams)

[0129] The preparation of pharmaceutical composition mixture of the present invention

[0130] Eucommia 450g Scutellaria baicalensis (manufactured) 100g Capillary 350g

[0131] Shanzhi (stir-fried) 150g Rhubarb 25g Tianjihuang 400g

[0132] White fresh skin 300g Poria cocos 250g Salvia miltiorrhiza 200g

[0133] Turmeric 50g

[0134] The above ten flavors are soaked in water for 1 hour and then decocted 3 times. For the first time, add water 10 times the total weight of the original medicinal materials, and for the second time add water 8 times the total weight of the original medicinal materials. After each boiling, continue decocting for 1 hour, filter Take the filtrate, discard the dregs, combine the three medicinal liquids, and after standing for 24 hours, take the supernatant and concentrate to 1000 ml (each ml contains 2.27 grams of crude drug), after standing for 24 hours, filter the supernatant, and ...

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