Application of traditional Chinese indian lettuce in preparation of diabetes drugs

A technology of kudzu and diabetes, which is applied to the application field of Chinese kudzu in the preparation of medicines for treating diabetes, and can solve the problems of low antioxidant activity and the like

Active Publication Date: 2009-10-28
SHANXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Zhao Aiyun et al. (Natural Product Research and Development, 2000, 12(3): 42-44) studied the antioxidant activity of the methanol extracts of more than 20 kinds of plants by DPHH

Method used

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  • Application of traditional Chinese indian lettuce in preparation of diabetes drugs
  • Application of traditional Chinese indian lettuce in preparation of diabetes drugs
  • Application of traditional Chinese indian lettuce in preparation of diabetes drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] Weigh 700g of Chinese bitter gourd, add 10 times the amount of water, soak for 0.5h, decoct for 1h, filter, add 10 times the amount of water to the dregs, decoct for 1h, filter, combine the filtrate, centrifuge, Take the supernatant and concentrate it into a thick paste, dry it in an oven at 65°C, grind it into a fine powder, pass it through a 100-mesh sieve, and obtain a fine powder of Chinese bitter root extract containing 4g crude drug / g.

Embodiment 2

[0080] Take an appropriate amount of the fine powder of Chinese bitter root extract obtained in Example 1, add it to 4 times the amount of the melted to clear matrix (PEG4000: PEG6000 = 2: 1) and mix, drop into the simethicone cooling liquid, Shrink into pills, take out the pellets, dry them and make them into dripping pills.

Embodiment 3

[0082] Take an appropriate amount of the fine powder of Chinese bitter root extract obtained in Example 1, add a conventional amount of starch and magnesium stearate, and make tablet products according to known tablet technology and equipment.

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PUM

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Abstract

The invention relates to a new application of traditional Chinese indian lettuce in the pharmaceutical field, in particular to the application of drugs for curing or preventing diabetes. Experiments prove that rats suffering from diabetes due to streptozotocin significantly decrease urinary output, put on weight gradually and significantly decrease blood sugar level after being fed with the aqueous extract of traditional Chinese indian lettuce. Experiments also prove that no evident toxic side effect produces after rats are fed with the traditional Chinese indian lettuce by 200 times more thanan adult equivalent dose by the maximum gavage amount to the rat (0.4 ml/10g).

Description

technical field [0001] The present invention relates to a new application of Chinese bitter root, in particular to the new use of Chinese bitter root in the field of pharmacy, especially in the preparation of medicines for treating diabetes. Background technique [0002] Ixeris chinensis (Thunb) Nakai is the dry whole plant of the perennial herb of the family Asteraceae Ixeris chinensis, also known as Ixeris chinensis (Thunb) Nakai, alias Ixeris chinensis, bitter vegetable, Yunnan bitter vegetable, Tian bitter vegetable, sharp leaf bitter dishes etc. It is widely distributed in almost all provinces and regions of the country, except for alpine grasslands, meadows, deserts, Gobi deserts and salt deserts where the climate and soil conditions are extremely harsh. Chinese bitter cabbage is a wild vegetable with well-developed leaves and a bitter taste, but it is very refreshing. It has a long history of eating in my country and is currently cultivated in a small amount. The ro...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61P3/10
Inventor 裴妙荣韩桂香
Owner SHANXI UNIV OF CHINESE MEDICINE
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