Multi-channel chip for cholera diagnosis based on structural conductive macromolecular material technology

Abstract

The invention relates to a multi-channel chip for cholera diagnosis based on a structural conductive macromolecular material technology, belonging to the test field. The invention aims to aid rapid and low-cost fulminating infectious disease cholera diagnosis which is one of medical technical progress expectations. The chip is provided with three micro liquid storage tanks and is characterized bycomprising capillary channels in parallel construction containing four micro channels mutually connected in parallel; four fibrous working electrodes are respectively mounted in the four micro channels; and four antibody substances, i.e. a cholera TP0821 antibody, a cholera TP0319 antibody, a cholera TP 0624 antibody and a cholera TP0139 antibody are respectively arranged on the surfaces of the four fibrous working electrodes which are originally made of a thermal-decomposition conductive macromolecular material. The chip has low cost and multiple channels.

Description

technical field [0001] The invention relates to a multi-channel chip for cholera diagnosis based on structural conductive polymer material technology, which belongs to the testing field. Background technique [0002] Cholera is a severe infectious disease caused by Vibrio cholerae, which belongs to the international quarantine infectious disease and is also one of the pathogens of Class A infectious diseases stipulated in the Law of the People's Republic of my country on the Prevention and Control of Infectious Diseases. The disease is characterized by acute onset, rapid spread, and wide coverage, which can cause local and worldwide outbreaks; it is an infectious disease that seriously endangers human health and life. Vibrio cholerae is a pathogenic bacterium that causes severe diarrhea in infected persons. As an international quarantine infectious disease-cholera, the pathogenic diagnosis of cholera is based on the detection of Vibrio cholerae O1 or O139 Vibrio cholerae. ...

AI Technical Summary

Problems solved by technology

[0007] At present, in the field of microfluidic chip technology, the technology of using multiple characteristic antibodies of cholera to simultaneously detect and rapidly diagnose cholera has not been reported; It is the basic material of the working electrode. The use of this expensive metal material increases the manufacturing cost of the related chip. In view of the known danger of the related infectious diseases detected by the chip, the microfluidic chip used for the detection of related diseases There are unsafe factors in the gold recycling work in China, and related unsafe factors will increase the difficulty of gold recycling work and increase the cost of gold recycling operations, which may cause the loss of precious resource gold due to the practical consideration of economic gains and losses. Obviously, this A technical defect also needs to be eliminated

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