Compound fleece-flower root oral liquid, preparation method thereof and quality control method
A technology of compound Shouwu and oral liquid, which can be used in pharmaceutical formulations, measuring devices, medical preparations containing active ingredients, etc., can solve problems such as deficiency, and achieve the effects of improving dementia, improving intelligence, and increasing intelligence.
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Embodiment 1
[0020] The compound Shouwu oral liquid is made from the following raw materials by weight: Polygonum multiflorum 266.7g, Lycium barbarum 200g, Polygala 166.7g, Shichangpu 133.3g, Mulberry 133.3g, Ginseng 66.7g, Jujube 33.3g, Simple syrup 360ml, Sodium benzoate 2.7g, made into 1000ml.
Embodiment 2
[0022] The preparation method of compound Shouwu oral liquid: take the above seven flavors, extract the volatile oil from calamus and mulberry by steam distillation, and collect the distilled aqueous solution in another device; add 8, 6, and 6 times the amount of water to decoct the dregs and other five flavors such as Polygonum multiflorum for three times, Each time 1.5 hours, the decoction was combined, filtered, the filtrate was combined with the above aqueous solution, concentrated to 450ml, added ethanol until the alcohol concentration was 60%, stirred, left to stand for 24 hours, filtered, concentrated under reduced pressure to a relative density of 1.5( 80°C) thick paste, dilute with water to 450ml, relative density 1.20-1.25 (50°C); freeze at -5°C for 24 hours, melt at room temperature, filter, add simple syrup 360ml, sodium benzoate 2.7g and the above volatile oil , add water to 1000ml, stir, filter, dispense, sterilize, and obtain.
experiment example 1
[0024] Identification method of Compound Shouwu Oral Liquid
[0025] This method includes any one or combination of the following:
[0026] (1) Take 50ml of this product, add ether to extract 2 times, 20ml each time, discard the ether solution, extract 3 times with n-butanol saturated with water, 30ml each time, combine the n-butanol solution, concentrate to about 30ml, and use normal Butanol-saturated 2% sodium hydroxide solution was extracted twice, 30ml each time, the lye was discarded, and then 30ml of n-butanol-saturated water was used to extract, the water layer was discarded, evaporated to dryness, and the residue was dissolved by adding 1ml of methanol, as The test solution; take another ginsenoside Rg 1 For the reference substance, add methanol to make a solution containing 1 mg per 1 ml, as the reference substance solution; test according to thin-layer chromatography (Chinese Pharmacopoeia 2005 edition one appendix VI B), draw each 6 μ l of the above-mentioned two s...
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