Production technology of grape pip and grape skin extract

A production process, grape seed technology, applied in the field of grape seed and skin extract production process, can solve the problems of low quality, low quality and value, low content, etc., to increase content, improve product quality and value, and effectively The effect of increasing the content of ingredients

Inactive Publication Date: 2010-05-12
应维强
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Problems solved by technology

[0002] At present, grape seed and skin extracts, as a natural radical scavenger and antioxidant, are more and more popular due to their anti-aging, anti-tumor, anti-cancer and prevention of cardiovascular diseases and arteriosclerosis. At present, the active ingredients extracted from grape seeds and skins are mainly polyphenols, mainly catechins, and catechins or epicatechins are used as units to form dimers, Proanthocyanidins composed of oligomers such as trimers, and the medicinal value of oligomeric proanthocyanidins are more and more recognized by people. At present, the extraction methods for grape seeds

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  • Production technology of grape pip and grape skin extract
  • Production technology of grape pip and grape skin extract
  • Production technology of grape pip and grape skin extract

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[0021] Combine figure 1 As shown, the production process of grape seed and skin extract of the present invention includes the following steps:

[0022] 1. Extract active ingredients from grape seeds and skin

[0023] 1.1. Extraction: add 8 times 50-70% ethanol to the collected grape seeds and skins, and extract the grape seeds and skins three times, the first time is 3 hours, the second time is 2.5 hours, and the third time is 2 Hours, the extraction temperature is 70 degrees, and then the extract is collected.

[0024] 1.2. Ethanol recovery: vacuum evaporate the extract, recover the ethanol, and cool the extract with water for later use.

[0025] 1.3 Centrifugation: The extract is centrifuged at 1,000 revolutions / min, 4400 revolutions / min, and 14000 revolutions / min in three stages, and the supernatant is collected after centrifugation. Among them, the first-stage centrifugation mainly removes the large particles of impurities in the extract, the second-stage centrifugation mainly re...

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Abstract

The invention relates to a production technology of grape pip and grape skin extract, belonging to the technical field of plant extract. The production technology comprises the following steps: adding the raw materials of grape pip and grape skin into 50-70% of alcohol the volume of which is eight times of the raw materials; extracting the grape pip and grape skin at the extracting temperature of 70 DEG C for three times; collecting the extraction solution, vacuum evaporating, recovering the alcohol and collecting supernate after centrifugation; carrying out chromatographic column on the centrifuged extraction solution in macroporous resin with the diameter height ratio of 1:10; eluting with 5-15% of alcohol in batch until the eluate is clear; desorbing with 70% of alcohol, collecting the desorption solution after desorption; carrying out chromatographic column on the centrifuged extraction solution in macroporous resin with the diameter height ratio of 1:10; collecting the desorption solution, decompressing and recovering the alcohol, concentrating into thick paste, and vacuum drying to obtain the grape pip and grape skin extract. The production technology of the invention adopts multi-time extraction, multistage centrifugation and two-time desorption method of crude extract and fine extract, thus greatly improving the content of effective components.

Description

technical field [0001] The invention relates to a production process of grape seed and skin extract, which belongs to the technical field of plant extraction. Background technique [0002] At present, grape seed and skin extracts, as a natural radical scavenger and antioxidant, are more and more popular due to their anti-aging, anti-tumor, anti-cancer and prevention of cardiovascular diseases and arteriosclerosis. At present, the active ingredients extracted from grape seeds and skins are mainly polyphenols, mainly catechins, and catechins or epicatechins are used as units to form dimers, Proanthocyanidins composed of oligomers such as trimers, and the medicinal value of oligomeric proanthocyanidins are more and more recognized by people. At present, the extraction methods for grape seeds and skins mainly include the following: 1. Solvent 2, precipitation method; 3, adsorption column chromatography etc., but adopt the above-mentioned method to extract the active ingredient ...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61P39/06A61K131/00
Inventor 应维强应维潮应浩应诗雨
Owner 应维强
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