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Adinandra nitida leaf flavone oral tablet and preparation method

A technology of flavonoids and bright leaves of poplar leaves, applied to medical preparations containing active ingredients, pharmaceutical formulas, medical preparations with no active ingredients, etc., can solve the problems of low development and utilization of poplar leaves of bright leaves

Inactive Publication Date: 2011-11-02
GUANGZHOU UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the development and utilization of bright-leaved poplar leaves are still very low, mainly for primary tea processing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Weigh 100g of poplar leaves, add 10 times the amount of water, heat and decoct, boil for 30 minutes, vacuum filter while hot, add 10 times the amount of water to the filter residue, heat and boil for 30 minutes, then filter while hot, combine the two filtrates and cool After reaching room temperature, some crystallization will be found on the wall and bottom of the container. Transfer the filtrate to a refrigerator at 0°C for 5 hours, then centrifuge at 1000rpm for 30 minutes to separate the pale yellow-green precipitate, and place the precipitate in an oven at 85°C. Dry for 1 hour, then add 10g of sucrose, 1g of citric acid, and 1g of dextrin, mix evenly, spray water as the binder and place it in a fluidized bed granulator for granulation. The size of the particles should pass through a 16-mesh sieve. After adding 0.3g of magnesium stearate to the prepared granules, use a rotary tablet machine to process them into round oral tablets. The weight of each tablet is control...

Embodiment 2

[0013] Weigh 100g of poplar leaves, add 30 times the amount of water, heat and decoct, boil for 30 minutes, vacuum filter while hot, add 30 times the amount of water to the filter residue, heat and boil for 30 minutes, then filter while hot, combine the two filtrates and cool After reaching room temperature, some crystallization will be found on the wall and bottom of the container. Transfer the filtrate to a refrigerator at 4°C for 8 hours, then centrifuge at 5000rpm for 10 minutes to separate the pale yellow-green precipitate, and place the precipitate in an oven at 100°C. Dry for 1 hour, then add 30g of sucrose, 2g of citric acid, 5g of dextrin, and 3g of gum arabic, mix evenly, spray water as the binder and place it in a fluidized bed granulator for granulation. It is advisable to use a mesh sieve. After adding 0.3g of magnesium stearate to the prepared granules, they are processed into oral tablets with circular and bright-leaved poplar plant patterns with a rotary tablet ...

Embodiment 3

[0015] Weigh 0.5 kg of poplar leaves, add 50 times the amount of water, heat and decoct, boil for 60 minutes, vacuum filter while hot, add 50 times the amount of water to the filter residue, heat and boil for 60 minutes, then filter while hot, and combine the two filtrates After cooling to room temperature, some crystallization will be found on the container wall and the bottom of the container. Transfer the filtrate to a refrigerator at 4°C for 10 hours, then centrifuge at 5000rpm for 30 minutes to separate the pale yellow-green precipitate, and place the precipitate in an oven at 100°C After drying for 1 hour, add 100 g of sorbitol, 50 g of glucose, 25 g of citric acid, 50 g of dextrin, and 25 g of gum arabic, and mix evenly. It is advisable to pass through a 16-mesh sieve. After adding 2.5g of magnesium stearate to the prepared granules, use a rotary tablet press to process them into oral tablets with round shapes and plant flavonoids. The weight of each tablet is controlled...

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Abstract

The invention discloses an adinandra nitida leaf flavone oral tablet and a preparation method which belong to the technical field of the processing of health-care products. The adinandra nitida leaf flavone oral tablet takes flavonoid extracted from adinandra nitida leaves as a main raw material, comprises the following components according to the weight ratio in a formula: 100-500g of adinandra nitida leaf, 10-150g of sweetening agent, 1-25g of citric acid, 1-50g of dextrin, 0-25g of acacia and 0.3-2.5g of magnesium stearate, and is prepared by tabletting. A product is in a slight green-yellow colour and has sweet mouth feel. The adinandra nitida flavone oral tablet does not need to be taken with water, can be quickly dissolved when encountering saliva in the oral cavity, is convenient to take, is quick to absorb and can give full play to the preventing and treating function of a flavone compound contained in the adinandra nitida leaves to the health care of a human body and diseases.

Description

technical field [0001] The invention belongs to the technical field of health care products processing, and in particular relates to an oral buccal tablet with flavonoids contained in the leaves of poplaria glabrata as the main raw material and a preparation method thereof. Background technique [0002] Adinandra nitida Merr.ex H.L.Li is a plant of the genus Adinandra in the family Theaceae. It is mainly distributed in Guangxi, Guangdong, Guizhou and other provinces in my country, and is rich in resources. Folks use the tender leaves of this plant to make health tea to prevent and treat various inflammations, unknown swellings and pains, trauma and other diseases, all of which have received satisfactory curative effects and have no toxic and side effects. Recent studies have shown that the main physiologically active components in the leaves of Populus radiata are flavonoids, and the total flavonoid content exceeds 20%. Flavonoids are one of the essential nutrients for the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/82A61K9/20A61K47/36A61P1/02A61P1/04A61P9/12A61P25/32
Inventor 战宇彭胜意
Owner GUANGZHOU UNIVERSITY
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