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Medicine composition with functions of narcotizing in operation and alleviating pain after operation

A composition and post-operative technology, applied in the direction of drug combination, non-central analgesics, anesthetics, etc., can solve problems such as unavoidable side effects, delay treatment, and affect recovery, so as to reduce patient pain, avoid pain, and facilitate surgery The effect of the operation

Inactive Publication Date: 2010-06-16
刘振起
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Surgery has long been an indispensable way to treat some diseases. There will be incisions and wounds after surgery, which will cause severe pain and affect postoperative recovery. Some people give up surgery because of fear of pain and adopt conservative methods. Therapy, so as to delay treatment, especially since the emerging of anorectal hemorrhoids, there is no ideal drug for postoperative pain relief, such as a variety of injection drugs: methylene blue, fentanyl, meperidine; oral drugs: Fenbid, luotongding, analgesic tablets, codeine, amphenidine, narcotics and other analgesics, side effects are inevitable, such as urinary retention accounting for 75%, anal numbness, incontinence accounting for 65%, burning sensation 45% and dizziness and headache 50%

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Tecaine 5.25kg Bupivacaine 15kg Frankincense 100kg

[0045] Cyperus Cyperus 100kg Patriarch Hemp 100kg Paeoniae Alba 100kg

[0046] Menthol 100kg,

[0047] The above-mentioned raw materials are added into conventional excipients according to a conventional process and sterilized at high temperature to prepare an injection. Operating procedures: Anal canal anesthesia, the site is at the lower edge of the tooth line, the drug is infiltrated on the base of the tooth line, and the anesthetic is directly injected into the internal sphincter and levator ani at the tooth line and the base of internal hemorrhoids, which can not only make the operative field clear, but also Avoid pain, bloating, feeling of defecation, urinary retention caused by surgery, and fully relax the anal canal, which is convenient for operation.

Embodiment 2

[0049] Tecaine 1kg Bupivacaine 18kg Frankincense 55kg

[0050] Cyperus Cyperus 145kg Patriarch Hemp 55kg Paeoniae Alba 145kg

[0051] Menthol 55kg;

[0052] The above-mentioned medicines are prepared into freeze-dried powder injections by adding conventional auxiliary materials according to conventional processes.

Embodiment 3

[0054] Tecaine 9kg Bupivacaine 7kg Frankincense 130kg

[0055] Cyperus Cyperus 70kg Patriarch Hemp 130kg Paeoniae Alba 70kg

[0056] Menthol 130kg;

[0057] The above raw materials are prepared by adding conventional auxiliary materials according to conventional processes to make injections.

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PUM

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Abstract

The invention discloses a medicine composition with the functions of narcotizing in an operation and alleviating pain after the operation. The medicine composition comprises tetracaine, bupivacaine, mastic, rhizoma cyperi, girald daphne bark, white peony root and menthol. The medicine composition is added with conventional auxiliary materials in pharmacy according to a conventional process to prepare a clinically acceptable medicament form. The medicine composition is a medicine for injecting and narcotizing in the operation and alleviating pain in a long acting way after the operation and is already applied to clinic successfully throughout the years. The medicine composition can enable the surgical field to be clear, can also avoid pain, sagging distention, frequent defecation and uroschesis caused by the operation, can loosen the anal canal fully and is convenient for the surgical operation.

Description

technical field [0001] The present invention relates to a kind of pharmaceutical composition, especially relates to a kind of pharmaceutical composition which has the function of anesthesia during operation and pain relief after operation. Background technique [0002] Surgery has long been an indispensable way to treat some diseases. There will be incisions and wounds after surgery, which will cause severe pain and affect postoperative recovery. Some people give up surgery because of fear of pain and adopt conservative methods. therapy, so as to delay treatment, especially since the emergence of anorectal hemorrhoids, so far there is no ideal drug for postoperative pain relief, such as a variety of injection drugs: methylene blue, fentanyl, meperidine; oral drugs: Fenbid, luotongding, analgesic tablets, codeine, amphencodene, narcotics and other painkillers, side effects are unavoidable, such as urinary retention accounting for 75%, anal numbness, incontinence accounting fo...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P23/00A61P25/04A61P29/00A61K31/045A61K31/245A61K31/445
Inventor 刘振起
Owner 刘振起
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