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Medicinal application of ethyl acetate extracts from Gastrodia elata Blume in treating ischemic cerebrovascular disease

A technology of ethyl acetate extraction and cerebrovascular disease, which is applied in the field of medical application of Gastrodia elata ethyl acetate extract to treat ischemic cerebrovascular disease, and can solve problems such as the treatment and application of ischemic cerebrovascular disease that have not yet been discovered

Inactive Publication Date: 2010-06-16
YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Application Information

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Problems solved by technology

The Gastrodia elata products that have been developed are mainly used for the treatment of neurasthenia, neurasthenia syndrome and angioneurotic headache, etc., but no phenolic components of Gastrodia elata ethyl acetate extract have been found for the treatment of ischemic cerebrovascular diseases

Method used

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  • Medicinal application of ethyl acetate extracts from Gastrodia elata Blume in treating ischemic cerebrovascular disease

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Abstract

The invention discloses medicinal application of ethyl acetate extracts from Gastrodia elata Blume in treating ischemic cerebrovascular disease. The Gastrodia elata Blume is ground, extracted by ethanol, and is concentrated under reduced pressure to obtain an ethanol extract; the ethanol extract is extracted by ethyl acetate, and the ethyl acetate is concentrated and recovered to mainly obtain a group of phenol components; and total phenols or a single phenol component contained in the extracts is used for preparing medicaments for treating the ischemic cerebrovascular disease. The medicaments can be prepared into preparations such as tablets, pills, granules, capsules, oral liquid, paste and the like; and the phenol components have the effect of protecting brain by reducing lipid peroxidation and lightening calcium overload, and play an important role in preventing and treating the ischemic cerebrovascular disease.

Description

Technical field: The invention relates to the technical field of medicinal application of Gastrodia elata ethyl acetate extract for treating ischemic cerebrovascular disease. Background technique: Ischemic cerebrovascular diseases (ICVD) is one of the most important diseases in cerebrovascular diseases. For example, in my country, there are more than 1.5 million new cases every year, 1 million deaths, and more than 6 million total patients , about 3 / 4 of the survivors left sequelae of varying degrees, and more than 40% were severely disabled. Therefore, ICVD, tumors, and cardiovascular diseases are also called the three major diseases that seriously threaten human health. Find effective treatments for ICVD. Drugs have great practical significance. Drug treatment of ischemic cerebrovascular disease mainly through two ways: one is thrombus dissolution, and the other is neuroprotection. It aims to restore the blood supply in the ischemic area of ​​the brain tissue, protect the...

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Application Information

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IPC IPC(8): A61K36/8988A61P9/10
Inventor 林青周宁娜李秀芳淤泽溥何晓山代蓉孙衍鲲
Owner YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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