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Vegetable drug compound preparation for treating urarthritis as well as preparation and application thereof

A technology for gouty arthritis and compound preparations, which is applied in the field of herbal medicine compound preparations and its preparation and application. It can solve the problems of hard to kill miscellaneous bacteria carried by the original drug, difficulty in ensuring the quality of the drug, and many impurities in the drug, and achieve the reduction of purine substances. The effect of saving and eliminating arthritic lesions and taking it conveniently

Inactive Publication Date: 2010-06-30
HONGKONG XIAOYUAN PHARMA GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese Patent Publication No. CN1144676A discloses "Tangfengling Medicinal Wine and Its Preparation Technology". This invention is made of medicinal wine made from traditional Chinese medicine soaked in white wine. Although it has a certain curative effect, it is not suitable for patients with heart disease, high blood pressure, pregnant women and non-drinkers.
Publication No. CN1070070C discloses "a traditional Chinese medicine for treating gout". The invention is composed of insect medicine and herbal medicine. The original medicine is crushed and directly made into pills or packed into capsules. It has good curative effect, but the original medicine has not been extracted. Direct powdering will result in many impurities in the medicine, the original medicine carries miscellaneous bacteria that are difficult to kill, and the dosage is large, and it is difficult to guarantee the quality of the medicine

Method used

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  • Vegetable drug compound preparation for treating urarthritis as well as preparation and application thereof
  • Vegetable drug compound preparation for treating urarthritis as well as preparation and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Take 450g of sylvestris, 450g of gentian, 225g of cassia twig, 300g of parasite, 300g of windproof,

[0055] 450g of eucommia, 225g of aconite, 300g of achyranthes, 300g of psoralen, 300g of Qianghuo,

[0056] Tuckahoe 300g, Angelica 450g, Ligusticum chuanxiong 300g, Red Medicine 300g, Raw Rehmannia 300g,

[0057] 300g Alisma, 450g Salvia, 450g Astragalus, 150g Licorice.

[0058] The above nineteen flavors, add water to decoct twice, add 10 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second time, decoct for 1.5 hours, filter, combine the filtrate, take the supernatant and concentrate it into relative A clear paste with a density of 1.30 to 1.35 (90°C) is added with an appropriate amount of dextrin, dried under reduced pressure at 60°C, crushed, passed through a 40-mesh sieve, dried, mixed in an appropriate amount of lubricant, filled into capsules, and made into 1000 grains.

Embodiment 2

[0060] Take 600g of sylvestris, 600g of gentian, 200g of cassia twig, 200g of parasite, 200g of windproof,

[0061] 500g eucommia, 200g aconite, 200g achyranthes, 200g psoralen, 200g Qianghuo,

[0062] Poria 200g, Angelica 600g, Ligusticum chuanxiong 200g, Red Medicine 200g, Raw Rehmannia 200g,

[0063] 200g Alisma, 500g Salvia, 600g Astragalus, 200g Licorice.

[0064] For the above 20 flavors, add water to decoct twice, add 10 times the amount of water for the first time, decoc for 2 hours, add 8 times the amount of water for the second time, decoct for 1.5 hours, filter, combine the filtrate, take the supernatant to concentrate Add appropriate amount of dextrin to extract with density of 1.10 to 1.15 (90°C), spray dry, pass through a 40-mesh sieve, dry, stir in appropriate amount of lubricant magnesium stearate, fill it into capsules, and make 1000 tablets, ready to be obtained.

Embodiment 3

[0066] Take 400g of sylvestris, 400g of gentian, 275g of cassia twig, 275g of parasite, 275g of windproof,

[0067] Eucommia 300g, Aconite 275g, Achyranthes 275g, Psoralen 275g, Qianghuo 275g,

[0068] Poria cocos 275g, Angelica 400g, Ligusticum chuanxiong 275g, Red medicine 275g, Raw land 275g,

[0069] Alisma 275g, Danshen 300g, Astragalus 400g, Licorice 275g.

[0070] For the above 20 flavors, add water to decoct twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1.5 hours, filter, combine the filtrate, and concentrate to a specific gravity of 1.08-1.18 ( 90℃), spray dried, add appropriate amount of medicinal dextrin, granulate, compressed tablet 0.5g each, film coating.

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Abstract

The invention relates to a vegetable drug compound preparation for treating urarthritis, which comprises the following components of radix angelicae pubescentis, large-leaved gentian, cassia twig, Korthalsella japonica, divaricate saposhnikovia root, processed radix aconiti lateralis, the root of bidentate achyranthes, fructus psoraleae, notopterygium root, poria cocos, angelica sinensis, ligusticum wallichii, rubefacient, the dried rhizome of rehmannia, the rhizome of oriental water plantain, the root of red-rooted salvia, astragalus mongholicus and liquorice. A preparation method of the vegetable drug compound preparation comprises the following steps of: according to the formula, adding 4-12 times of water, decocting for 1-3 h and filtering out medicine juice; adding 4-12 times of water, decocting for 0.5-2 h, filtering out medicine juice, merging the decocting solution in the two steps, standing, leaching supernatant, condensing the supernatant to have the proportion of 1.08-1.35, drying and adding medicine auxiliary materials to prepare the vegetable drug compound preparation. The vegetable drug compound preparation has the efficiencies of warming yang, easing pain, clearing heat, cooling blood, promoting blood circulation and stopping pain, can reduce blood uric acid, eliminate arthritis disease caused by uric acid crystal, prevent recrudescence and treat both principal and secondary aspect of disease. In addition, the vegetable drug compound preparation has the advantages of stable quality, convenient taking, high curative effect, no toxic and side effect and the like.

Description

Technical field [0001] The invention belongs to the field of botanical medicine compound preparation and its preparation and application, and particularly relates to a botanical medicine compound preparation for treating gouty arthritis and its preparation and application. Background technique [0002] Gout is a systemic disease caused by purine metabolism disorders. Due to the increase of uric acid in serum and body fluids, urate crystals are deposited in various mesenchymal tissues. When joints are affected, it is called gouty arthritis. Western medicine often uses allopurine, colchicine, glucocorticoids and other drugs to treat gout, but long-term use of these chemicals can cause side effects such as liver damage, gastrointestinal reactions, and neurotoxicity. [0003] Gouty diseases have rarely appeared in my country in the past. In recent years, with the improvement of living standards and changes in diet, the number of cases of this disease has increased significantly. Gouty...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61P19/02A61P19/06
Inventor 黄晓东张际忠赵正福
Owner HONGKONG XIAOYUAN PHARMA GROUP
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