9results about How to "Reduce savings" patented technology

The utility model discloses an anti-blocking engine oil filter which comprises an outer shell, the top of the outer shell is detachably connected with a top cover through threads, the top cover is provided with a plurality of oil inlet pipes, the inner sides of the oil inlet pipes are provided with spiral flow guide channels, the middle position of the top cover is provided with an oil outlet, and the lower side of the top cover is fixedly provided with a connecting ring. The lower side of the connecting ring is connected with a multi-filtering mechanism, the multi-filtering mechanism comprises an inner filter element framework, a middle filter element framework, an outer filter element framework, an inner-layer filter element, a middle-layer filter element and an outer-layer filter element, the inner filter element framework, the middle filter element framework and the outer filter element framework are all fixed with the connecting ring, the inner-layer filter element is fixedly mounted on the outer side of the inner filter element framework, and the outer-layer filter element is fixedly mounted on the outer side of the middle-layer filter element framework. A middle-layer filter element is fixedly mounted on the outer side of the middle filter element framework, and an outer-layer filter element is fixedly mounted on the outer side of the outer filter element framework. According to the utility model, impurities directly accumulated on the filter elements are reduced through the centrifugal effect, and then the quantity of impurities on each layer of filter element is reduced through multi-layer filtration, so that the risk of overall blockage is reduced.

This invention relates to mitochondrial-enriched extracellular vesicles, their preparation methods, and applications, which can effectively solve the drug problem in spontaneous intracerebral hemorrhage. The technical solution involves using platelets as raw material, and obtaining platelet-derived extracellular vesicles carrying active mitochondria through activation induction, differential centrifugation and fractionation, membrane filtration and elution enrichment. This achieves efficient and stable loading of functional mitochondria, and the resulting PEV Mito has a complete structure and uniform particle size, which can effectively maintain mitochondrial membrane potential and biological activity. It can achieve efficient delivery and intracellular internalization to damaged neurons and restore mitochondrial function. The PEV Mito prepared by this invention has high delivery efficiency and excellent biocompatibility, and can be used to prepare drugs for the treatment of intracerebral hemorrhage and secondary neurological injury, with good prospects for clinical translation.

The utility model belongs to the field of material curing equipment, and particularly relates to curing equipment for material production, which comprises a water tank. A condensation mechanism is arranged on the side face of the water tank, an electric telescopic rod is fixedly connected to the bottom of the water tank, a filter plate is arranged on the top of the electric telescopic rod, a first sliding groove is formed in the inner side of the water tank, a motor is fixedly connected to the side face of the water tank, and a screw rod is fixedly connected to the output end of the motor. The screw rod is rotationally connected with the first sliding groove, and the surface of the screw rod is in threaded connection with a first sliding block; the surface of the filter plate is scraped and cleaned, dirt is pushed to the edge, dirt accumulated at the top of the filter plate is reduced, the accumulated dirt is prevented from affecting the filtering efficiency of the filter plate, manpower is reduced, and the cleaning efficiency is improved.

The invention provides a water-saving sprinkling irrigation device for agriculture and forestry. The water-saving sprinkling irrigation device comprises a movable seat body, a first irrigation unit, a second irrigation unit and a recovery unit. A water supply tank is arranged at the top end of the movable seat body; the first irrigation unit is provided with a plurality of water spraying parts facing the ground and is used for irrigating seedlings and low crops; the second irrigation unit is provided with two spraying parts which are symmetrically arranged in the width direction of the movable seat body, and the spraying parts are used for spraying water or pesticide to the shrubs; and the recovery unit is arranged on the movable seat body, is provided with two collecting parts corresponding to the two spraying parts respectively, and is used for recovering the liquid medicine overflowing from the shrubs or the spraying parts. According to the water-saving sprinkling irrigation device for agriculture and forestry, the first sprinkling irrigation unit and the second sprinkling irrigation unit which can be independently controlled are arranged, the device can be matched with various different types of plant shuttle planting scenes, part of water / pesticide liquid can be recycled, the water-saving effect is remarkable, and practicability is high.

The utility model discloses a water pan and a duct type air conditioner. The water pan comprises a main body. The main body comprises a water collecting part, a diversion part and a drainage assembly, the first side of the water collecting part is connected with the diversion part, and the drainage assembly communicates with the water collecting part; wherein the flow guide part comprises at least two flow guide slopes, the at least two flow guide slopes are sequentially connected in the direction away from the water collection part, and the inclination angles of the flow guide slopes are sequentially increased in the direction away from the water collection part. The problem that in the prior art, condensate water in a water pan is difficult to drain from a drain pipe quickly can be solved.

The present application relates to a liquid crystal alignment agent which satisfies at least one selected from the group consisting of (I) and (II). (I): contains a polymer (A) having a repeating unit selected from the group consisting of a repeating unit represented by the following formula (1-a) and a repeating unit represented by the following formula (1-i), and an epoxy compound (B) represented by the following formula (2). (II): contains a reaction product of the polymer (A) and the epoxy compound (B).

This invention relates to the field of biomedical technology, and particularly to a responsive RNA delivery system for glioma, its preparation method, and its applications. By fusing the blood-brain barrier-penetrating peptide ANG-2 to mediate cross-blood-brain barrier delivery, and simultaneously combining it with Siglec-15-mediated immune targeting recognition, a dual-targeting mechanism is constructed. This guides the delivery system to accurately identify glioma lesions, significantly increasing the enrichment of the delivery system in the lesion area, laying the foundation for the efficacy of nucleic acid drugs, effectively improving the targeting and effectiveness of treatment, and avoiding damage to normal brain tissue. The dual stimulation release mechanism of acid response and reactive oxygen species response can accurately respond to endogenous stimuli within glioma lesions and cells. Through the synergistic combination of the GO-C14 carrier and charge-reversed polylysine, the loading efficiency of YTHDF2 siRNA is effectively improved, while simultaneously enhancing the cyclic stability of nucleic acid drugs in vivo.

The utility model discloses a flue gas waste heat recovery device convenient to maintain, and relates to the technical field of flue gas waste heat recovery, the flue gas waste heat recovery device convenient to maintain comprises a waste heat recovery equipment body, an air inlet of the waste heat recovery equipment body is provided with a filtering mechanism and a cleaning mechanism which are used in cooperation, and the filtering mechanism comprises a first mounting ring; the first mounting ring is located on one side of the waste heat recovery device body, an inner groove is formed in the first mounting ring, and a filter screen is movably inserted into the inner groove. By arranging the filter mechanism, dust at the smoke inlet can be filtered through the filter screen, dust accumulation in the flue gas waste heat recovery device body is reduced, and the waste heat recovery efficiency is improved. According to the flue gas waste heat recovery device, the filter screen can be cleaned and collected through the cleaning mechanism, so that dust on the surface of the filter screen can be reduced, and the circulation amount of an air inlet of the flue gas waste heat recovery device is larger.

The application provides an application of tRF-22 in preparation of a drug for delaying ovarian aging, and a nucleotide sequence of the tRF-22 is TTATTCGACTCCTGGCTGGGC. Through in-vivo and in-vitro experiments, it is proved that the tRF-22 can improve the degeneration of the aging ovarian tissue, reduce the expression of the aging marker, inhibit the secretion of the SASP factor, reverse the aging phenotype of the human ovarian granulosa cell, improve the proliferation activity, relieve the cycle arrest, reduce the apoptosis and the accumulation of the active oxygen. Mechanism research shows that the tRF-22 can inhibit the expression of BNIP3, repair the damage of the mitochondrial ultrastructure, restore the mitochondrial autophagy flux, improve the membrane potential, the ATP level and the oxygen consumption rate, and reshape the mitochondrial homeostasis. The application provides a new active molecule and an action target for the nucleic acid drug for delaying ovarian aging.