Ibuprofen slow-release suspension and preparation method thereof

Abstract

The invention relates to an ibuprofen slow-release suspension and a preparation method thereof, relating to medicines, in particular to the technical field of the pharmacy of chemical medicines. The preparation method of the ibuprofen slow-release suspension comprises the following steps of: firstly mixing a flavoring agent, an antiseptic and pure water, and heating to be prepared into simple syrup; preparing ibuprofen and glutin into an ibuprofen microcapsule; then mixing the simple syrup, the ibuprofen microcapsule and a suspending agent, adding edible pigments and the flavoring agent, and uniformly stirring. The invention has the advantages of simple process, easy production and operation, good curative effect of the medicines and convenient carrying and preservation.

Description

Ibuprofen sustained-release suspension and preparation method thereof Technical field The present invention relates to medicine, especially the pharmaceutical technology field of chemical medicine. Background technique Although the suspensions suitable for children with ibuprofen as the active ingredient on the market are added with correctives, they cannot completely conceal the pungent taste of the drug, and children have poor compliance. In order to obtain a satisfactory suspension effect, the ibuprofen is ground into an extremely fine powder during preparation. After the administration, the drug has a large contact surface with the stomach and a high concentration. Although it is rapidly absorbed, it has obvious side effects. In addition, after taking the ibuprofen suspension, the drug effect is maintained for a short time and must be taken multiple times, which brings great inconvenience to children and nursing staff. Summary of the invention The purpose of the present ...

AI Technical Summary

Problems solved by technology

Although the suspension suitable for children with ibuprofen as an active ingredient is added with a flavoring agent on the market, it cannot completely cover the pungent taste of the medicine, and children's compliance is poor.

In order to obtain a satisfactory suspension effect, the ibuprofen is ground into a very fine powder during preparation. After taking it, the contact surface between the drug and the stomach is large, and the concentration is high. Although it is absorbed quickly, it has obvious side effects

In addition, after the ibuprofen suspension is taken, the drug effect is maintained for a short time, and it must be taken many times, which brings great inconvenience to children and caregivers.