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Chinese medicinal composition for treating oviduct obstruction, and preparation method and application thereof

A technology of fallopian tube blockage and composition, which is applied in the field of medicine, can solve the problems of patients' pain, fallopian tube blockage, etc., and achieve the effect of neat and beautiful appearance, small dosage and rapid effect

Active Publication Date: 2011-11-16
广东爱民药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the main method to treat women's fallopian tube obstruction is surgical therapy. In mild to moderate cases, laparoscopy can be used to inject anti-inflammatory drugs into the fallopian tubes to eliminate inflammation. Or cut through laparoscopy to break down fallopian tube adhesions, so that the fallopian tubes "loosen". Or use Tubaloplasty, but the surgical treatment is a creative treatment, which will bring great pain to the patient
At present, no specific drug has been found to treat fallopian tube obstruction

Method used

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  • Chinese medicinal composition for treating oviduct obstruction, and preparation method and application thereof
  • Chinese medicinal composition for treating oviduct obstruction, and preparation method and application thereof
  • Chinese medicinal composition for treating oviduct obstruction, and preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0039] Take 800g Angelica, 800g Chishao, 600g Passepartout, 1200g Cyperus Cyperi, 600g Bupleurum, 600g Turmeric, 800g Saponaria thorn, 900g Patrinia, 1000g Daxueteng, add 12 times the amount of Angelica, Cyperus Cyperi and Curcuma Soak in water overnight, steam distillation to extract volatile oil, and the distilled aqueous solution is collected in another device. The dregs and the other six herbs are decocted twice with water, 1.5 hours each time, the decoction is combined, filtered, the filtrate is combined with the above aqueous solution, concentrated to a relative density of 1.10-1.15 (25°C), and ethanol is added to reduce the alcohol content. 70%, stand still for 12 hours, recover ethanol from the supernatant, concentrate to a thick paste with a relative density of 1.25-1.30 (70°C), dry under reduced pressure, grind into fine powder, and set aside. Take 1 part of volatile oil, 8 parts of beta-cyclodextrin, 80 parts of water, add water to beta-cyclodextrin, heat to dissolv...

Embodiment 2

[0041] Take 642g Angelica, 642g Chishao, 642g Passepartout, 856g Cyperus Cyperi, 428g Bupleurum, 642g Turmeric, 428g Saponaria thorn, 1071g Patrinia, 1071g Daxueteng, add 10 times the amount of Angelica, Cyperus Cyperi and Curcuma Soak in water overnight, steam distillation to extract volatile oil, and the distilled aqueous solution is collected in another device. The dregs and the other six herbs are decocted once with water, 1.5 hours each time, the decoction is combined, filtered, the filtrate is combined with the above aqueous solution, concentrated to a relative density of 1.05-1.10 (25°C), and ethanol is added to make the alcohol content to 70%, stand still for 12 hours, recover ethanol from the supernatant, concentrate to a thick paste with a relative density of 1.25-1.30 (80°C), dry under reduced pressure, crush into fine powder, and set aside. Take 1 part of volatile oil, 8 parts of beta-cyclodextrin, 80 parts of water, add water to beta-cyclodextrin, heat to dissolve...

Embodiment 3

[0043] Take Angelica 1099g, Chishao 774g, Passepartout 774g, Cyperus cyperi 922g, Bupleurum 628g, Curcuma 811g, Saponaria thorn 754g, Patrinia 996g, Daxueteng 1146g, add 12 times the amount of Angelica, Cyperus cyperi and turmeric Soak in water overnight, steam distillation to extract volatile oil, and the distilled aqueous solution is collected in another device. The dregs and the other six herbs are decocted twice with water, 2 hours each time, the decoction is combined, filtered, the filtrate is combined with the above aqueous solution, concentrated to a relative density of 1.10-1.15 (25°C), and ethanol is added to reduce the alcohol content. 60%, stand still for 12 hours, recover ethanol from the supernatant, concentrate to a thick paste with a relative density of 1.25-1.30 (90°C), dry under reduced pressure, grind into fine powder, and set aside. Take 1 part of volatile oil, 10 parts of beta-cyclodextrin, 100 parts of water, add water to beta-cyclodextrin, heat to dissolv...

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Abstract

The invention relates to a Chinese medicinal composition for treating oviduct obstruction, and a preparation method and application thereof, in particular to a Chinese medicinal composition for treating oviduct obstruction, and a preparation method of granules and application thereof, and belongs to the field of medicine. The oviduct obstruction or partially passable oviduct is the major cause for female infertility, and the oviduct obstruction cannot be treated by special-effect medicament at present. The Chinese medicinal composition consists of nine medicaments such as Chinese angelica, red paeony root, beautiful sweetgum fruit and the like, and the granules of the Chinese medicinal composition are prepared by aqueous extraction, filtering, alcohol extraction, concentration, drying under reduced pressure, pulverizing and pelleting by adding auxiliary materials. The Chinese medicinal composition has a strict formula, and is particularly suitable for treating the oviduct obstruction which belongs to qi depression to blood stasis in differentiation of traditional Chinese medical science. Experiments verify that the treatment effect is obvious. The Chinese medicinal composition hasthe advantages of reasonable and feasible preparation process, suitability for industrial production, quick absorption of the granules, quick response, moisture prevention, light resistance, good medicinal stability, clean and attractive appearance, small administration dosage and convenient production, transportation, carrying and storage.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for treating fallopian tube obstruction; and also relates to a preparation method and application of granules of the composition. Background technique [0002] Female infertility has brought great pain to many families. Blockage or blockage of fallopian tubes is an important cause of female infertility, accounting for about 1 / 3. The cause of lesions is mainly inflammation, but the rate of non-inflammatory lesions is gradually increasing, which cannot be ignored. The fallopian tube is the main channel for transporting sperm, ovum or fertilized eggs. It is a very important link for fertility and belongs to the category of blood vessels in the motherland's medicine. Any congenital developmental abnormalities or acquired lesions that cause inflammation of the fallopian tubes, resulting in blockage of fallopian tubes, or affect the normal...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/16A61P15/00
Inventor 玄振玉陆赛卫魏惠华
Owner 广东爱民药业有限公司
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