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Composition for improving memory

A technology for improving memory and composition, which is applied in the field of memory-improving health food, sesamin and total astragaloside composition, to achieve the effect of improving learning and memory function, without toxic side effects, and improving learning and memory function

Inactive Publication Date: 2010-12-15
HEFEI UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

There is no report on the use of sesamin and total astragalosides for improving memory

Method used

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  • Composition for improving memory
  • Composition for improving memory
  • Composition for improving memory

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A memory-improving composition is composed of sesamin powder extracted from sesame meal and total astragaloside powder extracted from astragalus membranaceus, and the ratio of the two is 1:1.

[0038] The extraction process of sesamin is as follows: Grind sesame meal into powder, add about 2 times the volume of n-hexane for stirring and degreasing for 3 hours, after filtering, add about 2 times the volume of n-hexane for the second degreasing, maintaining for 3 hours, Air dry. Accurately weigh a certain amount of powder, add 93% ethanol with a solid-liquid ratio of 1:8.5 (g / ml), stir at a water bath temperature of 55°C, extract for 2.5 hours, and repeat the extraction once. The extract was filtered, and the filtrate was steamed off part of the ethanol (residual volume <25mL) on a rotary evaporator, concentrated under reduced pressure, and vacuum-dried at 60°C, weighed to obtain sesamin powder, and determined the content of sesamin (mg / g). The properties of this produ...

Embodiment 2

[0047] A memory-improving composition is composed of sesamin powder extracted from sesame meal and total astragaloside powder extracted from astragalus membranaceus, and the ratio of the two is 1:2.

[0048] For the preparation of the tablet, the tablet is prepared according to the tablet preparation process. Each tablet contains 20mg+40mg of sesamin+astragalosides.

[0049] Others are with embodiment 1.

Embodiment 3

[0051] The sesamin powder extracted from the sesame meal and the total astragaloside powder extracted from the astragalus root are uniformly mixed in a ratio of 2:1.

[0052] For the preparation of capsules, capsules are prepared according to the capsule preparation process. Each capsule contains 40mg+20mg of sesamin+astragalosides.

[0053] Others are with embodiment 1.

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Abstract

The invention relates to a composition for improving memory. The composition is formed by uniformly mixing sesamin powder extracted from sesame seed meal and astragaloside powder extracted from raidx astragali, wherein the ratio of the sesamin powder to the astragaloside powder is 1-2:1-2; the sesamin content of the sesamin powder is over 50 percent; and the astragaloside content of the astragaloside powder is over 50 percent. A pharmacological test indicates that the composition has the effect of improving the learning and memory functions of an aging animal model, can act synergetic enhancement on physiological activity and improves respective learning and memory improving functions well; and a toxicological test indicates that the composition is safe to apply. The composition of the invention can be used for preparing health-care food and medicaments for assisting in improving the memory and can improve learning and memory dysfunction and coordination dysfunction caused by degenerative diseases of central nervous system, such as Alzheimer disease, Parkinsonism and the like.

Description

technical field [0001] The invention belongs to the fields of food and biomedicine, and in particular relates to a health-care food for assisting in improving memory, that is, a natural-sourced sesamin and total astragaloside composition. Background technique [0002] With the improvement of living conditions and the development of science and technology, people's demand for health food is getting stronger and stronger. After inquiry, among the 27 types of health food stipulated in my country, there are 90 kinds of health food with auxiliary memory function approved by the State Food and Drug Administration after December 12, 2003, accounting for 5293 kinds of domestic health food. The proportion is very small, and this type of product has great development prospects. Chemicals that enhance learning and memory include acetylcholinesterase inhibitors tacrine, piracetam, nimodipine, etc. Long-term use has certain toxic and side effects. Therefore, the development of health fo...

Claims

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Application Information

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IPC IPC(8): A23L1/29A23L33/00
Inventor 雷红蔡亮亮王毅
Owner HEFEI UNIV OF TECH
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