Traditional Chinese medicine for treating metrorrhagia and metrostaxis, gastrointestinal hemorrhage and traumatic hemorrhage and preparation method thereof

A technology for gastrointestinal bleeding and uterine bleeding, applied in traditional Chinese medicine and preparation of gastrointestinal bleeding and traumatic bleeding, and the field of treatment of uterine bleeding, can solve the problem that the clinical application value is not fully exerted, restricts the large-scale clinical application, and the bioavailability Low problems, to achieve significant clinical therapeutic economic significance, simple and feasible extraction and purification process, and the effect of improving the dissolution rate

Active Publication Date: 2011-01-12
XIAN CHIHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this product has the following problems: 1, the daily dosage is large, and the patient's compliance is poor, such as No. 0 capsule, three times a day, 2-4 capsules at a time; 2, low bioavailability, the prescription has 14 medicinal materials, of which 4 are extracted , and the rest are crude drug powders; 3. The treatment cycle is long, usually 3-5 weeks, which seriously restricts its clinical application in large quantities, resulting in the real clinical application value of the drug not being fully exerted

Method used

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  • Traditional Chinese medicine for treating metrorrhagia and metrostaxis, gastrointestinal hemorrhage and traumatic hemorrhage and preparation method thereof
  • Traditional Chinese medicine for treating metrorrhagia and metrostaxis, gastrointestinal hemorrhage and traumatic hemorrhage and preparation method thereof
  • Traditional Chinese medicine for treating metrorrhagia and metrostaxis, gastrointestinal hemorrhage and traumatic hemorrhage and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The weight components of each raw material in this example include: 48 parts of rhubarb and madder 1:1 extract, 20 parts of Panax notoginseng extract, 12 parts of donkey-hide gelatin, 12 parts of myrrh volatile oil clathrate, 20 parts of Baihe extract, 5 servings of dried blood.

[0031] The weight components of each raw material in this example are: 48 parts of rhubarb and madder 1:1 extract, 20 parts of Panax notoginseng extract, 12 parts of donkey-hide gelatin, 12 parts of myrrh volatile oil clathrate, 20 parts of Baiji extract, 5 servings of dried blood.

[0032] A modern traditional Chinese medicine prescription for treating uterine bleeding, gastrointestinal bleeding and traumatic bleeding and a preparation method thereof, comprising the following steps:

[0033] Step 1, preparation of rhubarb and madder 1:1 extract:

[0034]Take a total of 480 parts of rhubarb and madder at a ratio of 1:1, grind them through 10 meshes, first add 20% sulfuric acid 2.5 times the ...

Embodiment 2

[0045] The weight components of each raw material in this example include: 36 parts of rhubarb and madder 1:1 extract, 15 parts of Panax notoginseng extract, 8 parts of donkey-hide gelatin, 10 parts of myrrh volatile oil clathrate, 15 parts of Baiji extract, 3 servings of dried blood.

[0046] The weight components of each raw material in this example are: 36 parts of rhubarb and madder 1:1 extract, 15 parts of Panax notoginseng extract, 8 parts of donkey-hide gelatin, 10 parts of inclusion compound of myrrh volatile oil, 15 parts of Baiji extract, 3 servings of dried blood.

[0047] A modern traditional Chinese medicine prescription for treating uterine bleeding, gastrointestinal bleeding and traumatic bleeding and a preparation method thereof, comprising the following steps:

[0048] Step 1, preparation of rhubarb and madder 1:1 extract:

[0049] Take a total of 360 parts of rhubarb and madder at a ratio of 1:1, grind them through 14 meshes, add 20% sulfuric acid 2.0 times...

Embodiment 3

[0060] The weight components of each raw material in this example include: 24 parts of rhubarb and madder 1:1 extract, 10 parts of Panax notoginseng extract, 6 parts of donkey-hide gelatin, 6 parts of myrrh volatile oil clathrate, 10 parts of white root extract, 2 servings of dried blood.

[0061] The weight components of each raw material in this example are: 24 parts of rhubarb and madder 1:1 extract, 10 parts of Panax notoginseng extract, 6 parts of donkey-hide gelatin, 6 parts of myrrh volatile oil inclusion complex, 10 parts of bletilla root extract, 2 servings of dried blood.

[0062] A modern traditional Chinese medicine prescription for treating uterine bleeding, gastrointestinal bleeding and traumatic bleeding and a preparation method thereof, comprising the following steps:

[0063] Step 1, preparation of rhubarb and madder 1:1 extract:

[0064]Take a total of 240 parts of rhubarb and madder at a ratio of 1:1, crush them through 20 meshes, add 20% sulfuric acid 1.5...

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Abstract

The invention relates to a traditional Chinese medicine for treating metrorrhagia and metrostaxis, gastrointestinal hemorrhage and traumatic hemorrhage and a preparation method thereof. The traditional Chinese medicine comprises the following raw material components in part by weight: 24 to 48 parts of the extract of rhubarb and India madder root in the weight ratio of 1:1, 10 to 20 parts of notoginseng root extract, 4 to 12 parts of hide glue, 4 to 12 parts of myrrh volatile oil inclusion compound, 10 to 20 parts of common bletilla pseudobulb extract and 2 to 5 parts of dragon's blood. The preparation method comprises the following steps of: extracting all the extracts; mixing the extracts; adding lactose and aerosol; and mixing and filling the mixture to obtain capsules, or adding talcpowder, magnesium stearate, carboxymethyl sodium starch and the aerosol, uniformly mixing and directly tabletting. The traditional Chinese medicine has the advantages of simple and controllable process, short production cycle, low cost, exact curative effect of products, safety, no toxic or side effect, stable quality, convenient storage, contribution to clinical popularization and application of medical products, and obvious clinical therapeutic economic significance.

Description

technical field [0001] The invention relates to a modern traditional Chinese medicine prescription and a preparation method thereof, in particular to a traditional Chinese medicine for treating uterine bleeding, gastrointestinal bleeding and traumatic bleeding and a preparation method thereof. technical background [0002] Zhikang Capsule is the exclusive flagship product of Xi’an Qianhe Pharmaceutical Co., Ltd., which has been produced and sold for 15 years. It was included in the national medical insurance product catalog in 2006 for its remarkable anti-inflammatory, hemostatic, and wound-repairing therapeutic effects. Its products have obtained national patents, and its patent number is: ZL200510096362.6. The invention name is a drug for treating metrorrhagia, hematemesis and hematochezia. The invention patent discloses a drug and its capsules for treating metrorrhagia, hematemesis and hematochezia. Preparation. But this product has the following problems: 1, the daily d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/20A61K9/48A61P15/00A61P7/04A61P1/00A61P17/02A61K35/36
Inventor 胡小虎田继堂李文强赵宗平
Owner XIAN CHIHO PHARMA
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