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Preparation method of traditional Chinese medicine composition

A technology of composition and traditional Chinese medicine preparation, which is applied in the field of preparation of traditional Chinese medicine composition, can solve the problem of low transfer rate of active ingredients, and achieve the effect of stable quality

Active Publication Date: 2011-02-16
史志辉 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The present invention aims at the defect that the effective component transfer rate of the three traditional Chinese medicinal materials of rue, comfrey and wormwood is relatively low in the current extraction method, and provides a preparation method of a traditional Chinese medicine composition. The transfer rate of β, β′-dimethylacryloyl arcanin and eucalyptol was increased to more than 95%

Method used

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preparation example Construction

[0025] The invention discloses a preparation method of a traditional Chinese medicine composition, and those skilled in the art can refer to the content of this article and appropriately improve the process parameters to realize it. In particular, it should be pointed out that all similar replacements and modifications are obvious to those skilled in the art, and they are all considered to be included in the present invention. The method and application of the present invention have been described through preferred embodiments, and the relevant personnel can obviously make changes or appropriate changes and combinations to the method and application described herein without departing from the content, spirit and scope of the present invention to realize and Apply the technology of the present invention.

[0026] According to the present invention, the preparation method of the present invention is prepared by processing the following traditional Chinese medicine raw materials ...

Embodiment 1

[0030] The influence of each parameter of the preparation method of embodiment 1 Chinese medicine composition on extraction effect

[0031] The amount of water added for the first decoction was fixed, and the influence of the amount of water added for the second time and the time of two decoctions on the transfer rate of effective medicinal ingredients was investigated:

[0032]Weigh 50 kg of rue, 50 kg of comfrey, and 50 kg of wormwood, add water to decoct twice, add water for the first time to be 8 times the total weight of the three raw materials, decoct and extract according to the orthogonal test conditions, combine the decoction, filter The filtrate is concentrated under reduced pressure into a thick paste, dried and pulverized through a 100-mesh sieve to obtain a dry paste fine powder, which is accurately weighed to determine the total amount of dry paste fine powder, and adopts high performance liquid chromatography to measure the content of the above four active ingred...

Embodiment 2

[0058] Embodiment 2 The preparation method provided by the present invention affects the transfer rate of effective medicinal ingredients

[0059] Weigh 50kg of rue, 50kg of comfrey, and 50kg of absinthe wormwood, according to the optimal decoction conditions screened out in Example 1, add water for decoction twice, add 8 times the amount of water for decoction for 2.5h for the first time, and add water for the second time Decoct with 6 times the amount of water for 2 hours, collect the decoction, combine with the first decoction, filter, collect the filtrate, and concentrate to obtain the traditional Chinese medicine composition.

[0060] The prepared traditional Chinese medicine composition was tested to investigate the extraction effect.

[0061] The results are shown in Table 5.

[0062] Table 5 Verification results of water decoction extraction

[0063]

[0064] The results in Table 5 show that the decoction extraction verification results are consistent with the opt...

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine composition, belonging to the field of traditional Chinese medicines. The preparation method comprises the following steps of: mixing 100-900 parts of remote lemongrass herbs, 100-900 parts of lithospermum and 100-900 parts of wormwood; adding distilled water for the first time according to the mass ratio of 1:8, decocting for 2.5 h, and collecting the decoction liquid; adding distilled water according to the ratio of 1:6, decocting the raw materials for the second time for 2 h, and collecting the decoction liquid; and merging the two decoction liquids, filtering, collecting the extraction liquid and concentrating to obtain the traditional Chinese medicine composition. The preparation method increases the transfer rates of medicinal active ingredients of rutin, psoralen, beta, beta'-dimethylacryl alkannin and eucalyptol in remote lemongrass herbs, lithospermum and wormwood to be above 95% which is obviously higher than the transfer rates of effective ingredients of the traditional method. The preparation method improves medicinal effect and reduces cost.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a preparation method of a traditional Chinese medicine composition. Background technique [0002] Coronary heart disease, also known as ischemic heart disease or coronary atherosclerotic heart disease, is an episodic disease caused by temporary myocardial ischemia and hypoxia due to coronary atherosclerosis and coronary artery functional changes and insufficient blood supply. Chest pain and chest discomfort can spread to the neck, jaw, arms, back and stomach, accompanied by clinical syndromes such as dizziness, shortness of breath, sweating, chills, nausea and fainting. Severe cases may die from heart failure. Coronary heart disease is a common and frequently-occurring disease in the world today, which seriously threatens human health and life safety. [0003] Vitiligo is a common multiple pigmented skin disease. The disease is characterized by the formation of loca...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P9/10A61P17/00
Inventor 史志辉
Owner 史志辉
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