Device and method for measuring blood oxygen saturation of fundus retina

A saturation, retinal technology, applied in the field of devices for measuring blood oxygen saturation, can solve the problem of inability to measure retinal blood oxygen saturation in the fundus, and achieve the effect of avoiding achromatic operation and improving resolution

Inactive Publication Date: 2012-08-08
INST OF OPTICS & ELECTRONICS - CHINESE ACAD OF SCI
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Problems solved by technology

AOSLO combines adaptive optics technology and confocal scanning imaging technology to obtain high-resolution retinal images in vivo, but cannot measure the blood oxygen saturation of the fundus retina

Method used

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  • Device and method for measuring blood oxygen saturation of fundus retina
  • Device and method for measuring blood oxygen saturation of fundus retina
  • Device and method for measuring blood oxygen saturation of fundus retina

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Embodiment Construction

[0032] The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments. This embodiment uses the confocal scanning ophthalmoscope (AOSLO) based on adaptive optics as a platform, and uses spectral technology to measure the blood oxygen saturation of the retinal fundus. The process is as follows figure 1 , 5 shown; the specific steps are as follows:

[0033] (1) A device 32 capable of generating light of at least two specific wavelengths is composed of SLD light sources 1,2, collimator lenses 3,4 and optical filters 5,6. The central wavelengths of SLD light sources 1 and 2 are 680nm and 796nm respectively. After being collimated by collimating lenses 3 and 4, filters 5 and 6 are used to filter out two wavelengths of light with central wavelengths of 680nm and 796nm and a bandwidth of 7nm respectively. , where 796nm light is insensitive to blood oxygen saturation, and 680nm light is sensitive to blood oxygen saturat...

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Abstract

The invention relates to a method and device for measuring blood oxygen saturation of a fundus retina. The method is characterized by comprising the following steps of: taking a platform based on an ASOLO (adaptive optics confocal scanning laser ophthalmoscope), selecting a light with at least two different wavelengths as the light source of the ASOLO, enabling the retina to be sequentially imaged after correcting a fundus aberration by adopting the adaptive optics; generating defocus via a distorting lens for realizing the longitudinal chromatography of the retina so as to make the same position of a retina vessel imaged; registering the obtained high-resolution retinal image with multiple wavelengths, extracting a plurality of darkest spots and the spot arranged at a fixed distance fromthe darkest spots and in a tissue along with the vessel; and processing data to obtain the blood oxygen saturation of the vessel. In the invention, the high-resolution retinal image can be obtained by adopting the adaptive optics to correct the fundus aberration, and the blood oxygen saturation of the arteries, veins and capillaries of the fundus retina can be measured by processing a multi-wavelength image.

Description

technical field [0001] The invention relates to a device and method for measuring blood oxygen saturation, in particular to a device and method for measuring blood oxygen saturation of retinal arteries, veins and capillaries. Background technique [0002] A confocal scanning laser ophthalmoscope (CSLO) uses a laser as a light source, and the laser beam passes through an illumination pinhole to form a point light source, and scans every point on the focal plane in the sample. The illuminated spot on the specimen is imaged at the probe pinhole. The illumination pinhole and detection pinhole are conjugate with respect to the focal plane of the objective lens, and points outside the focal plane will not be imaged at the detection pinhole, so that a confocal image of the optical cross-section of the sample is obtained, which greatly improves the system efficiency. resolution. [0003] Adaptive optics (Adaptive Optics, AO) is a new optical technology developed in the past 20 yea...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/1455
Inventor 史国华李昊卢婧张雨东
Owner INST OF OPTICS & ELECTRONICS - CHINESE ACAD OF SCI
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