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Medicament for preventing and controlling damage of male reproduction by electromagnetic radiation and preparation method thereof

A technology of electromagnetic radiation and medicine, applied in the field of medicine, can solve problems such as inability to achieve clinical effects

Inactive Publication Date: 2011-05-11
ARMY MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Male reproductive damage caused by electromagnetic radiation and heat stress is fundamentally different from male infertility or reproductive dysfunction caused by endocrine, immune, pathogens, etc., especially in terms of damage mechanism. , Kidney-tonifying and Yang-invigorating drugs are used to treat male reproductive damage caused by electromagnetic radiation and heat stress, but satisfactory clinical results cannot be achieved.

Method used

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  • Medicament for preventing and controlling damage of male reproduction by electromagnetic radiation and preparation method thereof
  • Medicament for preventing and controlling damage of male reproduction by electromagnetic radiation and preparation method thereof
  • Medicament for preventing and controlling damage of male reproduction by electromagnetic radiation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Take 5kg of rehmannia glutinosa, 2.5kg of astragalus membranaceus, and 2.5kg of ginseng, mix them and crush them to 40 mesh, add them to the extraction tank, add 60kg of 80% ethanol, heat to 60°C, and reflux extraction twice, each time for 1 to 2 hours , filter and combine the extracts, recover ethanol from the alcohol extract, and concentrate to a relative density of 1.10-1.15 (60°C). Mix the medicinal dregs extracted from rehmannia glutinosa, astragalus root, and ginseng with 2.5kg Panax notoginseng, 2.5kg wolfberry fruit, and 1.5kg orange peel, add 80kg water, heat to boiling, decoct twice, each time for 2-3 hours, and collect at the same time Volatile oil, filter with Buchner funnel, concentrate the filtrate under reduced pressure to a thick paste, relative density is 1.10-1.15 (60°C), use ethanol precipitation method, add ethanol to make the solution alcohol content reach 70%, stir evenly, let stand , filtered, the filtrate was combined with the concentrated soluti...

Embodiment 2

[0038] Take 10kg of rehmannia glutinosa, 5kg of astragalus membranaceus, and 5kg of ginseng, mix them and crush them to 40 mesh, add them to the extraction tank, add 120kg of 80% ethanol, heat to 60°C, reflux extraction twice, each time for 1 to 2 hours, filter The extracts are combined, ethanol is recovered from the alcohol extract, and concentrated to a relative density of 1.10-1.15 (60° C.). Mix the medicinal dregs extracted from rehmannia glutinosa, astragalus root, and ginseng with 5kg panax notoginseng, 5kg wolfberry fruit, and 3kg tangerine peel, add 140kg water, heat to boiling, decoct twice, each time for 2 to 3 hours, and collect volatile oil at the same time, cloth Filter the filtrate under reduced pressure to a thick paste with a relative density of 1.10-1.15 (60°C). Treat it with ethanol precipitation, add ethanol to make the solution alcohol content reach 70%, stir evenly, let it stand, and filter , the filtrate is combined with the concentrated solution of rehma...

Embodiment 3

[0040]Take 12.5kg of rehmannia glutinosa, 7.5kg of astragalus membranaceus, and 7.5kg of ginseng, mix them and crush them to 40 mesh, add them to the extraction tank, add 160kg of 80% ethanol, heat to 60°C, and reflux extraction twice, each time 1-2 hours, filter and combine the extracts, recover ethanol from the alcohol extract, and concentrate to a relative density of 1.10-1.15. Mix the medicinal dregs extracted from rehmannia glutinosa, astragalus root, and ginseng with 7.5kg Panax notoginseng, 6kg wolfberry fruit, and 4kg tangerine peel, add 200kg water, heat to boiling, decoct twice, each time for 2 to 3 hours, and collect volatile oil at the same time, Buchner funnel suction filtration, the filtrate is concentrated under reduced pressure to a thick paste, the relative density is 1.10 ~ 1.15 (60 ° C), treated with ethanol precipitation method, add ethanol to make the solution alcohol content reach 70%, stir evenly, stand still, filter After filtration, the filtrate is com...

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Abstract

The invention relates to a medicament for preventing and controlling damage of male reproduction by electromagnetic radiation and a preparation method thereof. The medicament consists of root of rehmannia, raidx astragali, ginseng, pseudo-ginseng, barbary wolfberry fruit and tangerine peel. The medicament is prepared into capsules by extracting active ingredients by an ethanol refluxing method and a poaching and alcohol precipitation method. The medicament has obvious prevention and control effect on the damage of male reproductive function caused by electromagnetic radiation thermal effect and high-temperature thermal environment, is safe, does not have toxic or side effect and has effects of preventing, controlling and protecting reproductive health of professional population exposed in the electromagnetic radiation and the high-temperature thermal environment.

Description

technical field [0001] The invention belongs to the field of medicaments, in particular to a medicament for preventing electromagnetic radiation from damaging male reproduction and a preparation method. Background technique [0002] Electromagnetic radiation and high temperature have become the most frequently exposed harmful factors in the occupational environment, and their impact on the reproductive health of male occupational groups has attracted more and more attention. Due to the long time of electromagnetic radiation and high temperature acting on the human body during operation, it is difficult to protect individuals. Long-term high-dose electromagnetic radiation or high-temperature environmental exposure can cause damage to the male reproductive system, mainly manifested in loss of libido, impotence and premature ejaculation, and can also damage life. Sperm cells can temporarily affect the quality of semen and lead to infertility and deformity, and its harm cannot b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K9/48A61P15/00
Inventor 杨学森张荣华余争平洪多伦张广斌龚茜芬
Owner ARMY MEDICAL UNIV
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