Medicinal stent-graft for preventing and treating intrauterine adhesion

A technique for intrauterine adhesions and drug belts, applied in the field of medical devices, can solve the problems of incomplete coverage of new uterine cavity wounds and poor results, and achieve the effects of preventing re-adhesion, facilitating growth, and preventing intrauterine adhesions

Inactive Publication Date: 2011-07-13
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Balloons are also used to prevent adhesions after uterine cavity surgery, but the effect is not good because the uterine cavity is pear-shaped or approximately triangular, and the shape of the balloon is inconsistent with the shape of the uterine cavity. In other words, it cannot completely cover the new uterine cavity wound. prevent new adhesions from forming

Method used

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  • Medicinal stent-graft for preventing and treating intrauterine adhesion
  • Medicinal stent-graft for preventing and treating intrauterine adhesion
  • Medicinal stent-graft for preventing and treating intrauterine adhesion

Examples

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Effect test

Embodiment 1

[0024] Embodiment 1: A drug-coated stent for preventing intrauterine adhesions. The stent is woven into a palace-shaped basket by nickel-titanium alloy wires. The basket is coated with a layer of expanded polytetrafluoroethylene film, and at the same time, the film is sprayed with slow The drug-loaded layer is released, and the drug is adrenocortical hormone. The uterine-shaped basket coated with drug film is inserted into the uterine cavity through a catheter feeder and released. The membrane-coated basket is shrunk in the catheter of the catheter feeder in advance, and there is a push rod at the proximal end of the catheter. Finally, the push rod does not move, the overtube is retracted, and the mesh basket is gradually released. The basket automatically expands and fits closely with the uterine cavity, thereby isolating the direct contact with the endometrium of the uterine cavity and achieving the purpose of preventing intrauterine adhesions.

Embodiment 2

[0025] Embodiment 2: A drug-coated stent for preventing and treating intrauterine adhesions. The stent is woven into a palace-shaped basket by nickel-titanium alloy wires. The basket is coated with a layer of silica gel film, and a slow-release drug-loaded layer is sprayed on the outside of the film. The drug is estrogen plus progesterone. The uterine-shaped basket coated with drug film is inserted into the uterine cavity through a catheter feeder and released. The membrane-coated basket is shrunk in the catheter of the catheter feeder in advance, and there is a push rod at the proximal end of the catheter. Finally, the push rod does not move, the overtube is retracted, and the mesh basket is gradually released. The basket automatically expands and fits closely with the uterine cavity, thereby isolating the direct contact with the endometrium of the uterine cavity and achieving the purpose of preventing intrauterine adhesions.

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Abstract

The invention provides a medicinal stent-graft for preventing and treating intrauterine adhesion. The stent provided by the invention is a uterus-shaped mesh basket weaved by nickel-titanium alloy wires, wherein the mesh basket is coated by a biocompatible film, a sustained-release medicine-loading layer is sprayed outside the film, and the medicament comprises estrogen and progesterone. The medicinal film coated uterus-shaped mesh basket is placed in uterine cavity through a conduit conveyer to release; the mesh basket with the film is retracted in the conduit of the conduit conveyer in advance; a push rod is arranged at the end close to the conduit; and after the conduit conveyer is fed into the uterine cavity, the push rod does not move, an outer sleeve is withdrawn, the mesh basket with the film is gradually released, and the mesh basket automatically extends to be closely adhered to the uterine cavity, so that direct contact of endometria is isolated to achieve the purpose of preventing and treating the intrauterine adhesion. The medicinal stent-graft for preventing and treating the intrauterine adhesion has the advantage of wide application prospect.

Description

technical field [0001] The invention belongs to medical equipment, and relates to a gynecological intrauterine adhesion treatment device. In particular, it relates to a pear-shaped supporting mesh-shaped intrauterine stent coated with a drug-loaded membrane and a device for inserting and recovering the same. Background technique [0002] The front and back walls of the normal uterine cavity are close to each other, but because the endometrium is complete, adhesions are not easy to occur. Even if the endometrial functional layer is peeled off during menstruation, the basal layer is still intact, and adhesions will not occur. However, due to trauma to the cervix, endometrium, and muscularis caused by inflammation, trauma, surgery, and abortion, the inflammation of the wound will cause adhesions in the uterine cavity, uterine isthmus, and cervical canal. Once adhesions occur in the uterine cavity, there will be menstrual disorders. If there are only partial adhesions, menstrua...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M31/00A61L31/02A61L31/16A61L31/14A61L31/06A61L31/04
Inventor 孟艳顾兴中倪中华
Owner SOUTHEAST UNIV
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