Chinese medicine composition for treating knee osteoarthritis and preparation method thereof

A technology for knee osteoarthritis and composition, applied in the field of traditional Chinese medicine composition for treating knee osteoarthritis and its preparation, can solve the problems of large toxic and side effects, large trauma, short duration of curative effect, etc., achieve good pain relief, Low recurrence rate and good effect

Active Publication Date: 2011-09-21
YUEYANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL SHANGHAI UNIV OF CHINESE TRADITIONAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oral medicines are more toxic and side effects for patients, and surgery is usually more traumatic, whi

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The first traditional Chinese medicine combination for treating knee osteoarthritis of the present invention is obtained after grinding the six traditional Chinese medicines of 40g of raw strychnids, 40 of raw strychnids, 30g of raw fenugreek, 35g of frankincense, 50g of myrrh and 25g of angelica into powder. thing.

[0021] Use 500ml 75% ethanol to reflux extract 50min of the first traditional Chinese medicine composition, obtain concentrated extract after recovering ethanol, then add 400ml distilled water to dilute the gained concentrated extract, and place the dilution on a water bath to evaporate residual ethanol, then The pH value of the diluent was adjusted to 8.5, then 10 g of ethyl paraben was added and dissolved, and the mixture solution was kept at 3 °C and placed for 11 h before suction filtration. Finally, the obtained filtrate was supplemented with distilled water to 500 ml.

[0022] 35g of urea and 8ml of triethanolamine were added to the 500ml of filtrate...

Embodiment 2

[0026] After grinding 45g raw strychnids, 45g raw Chuanwu, 35g raw grass black, 40g frankincense, 55g myrrh and 30g angelica these six traditional Chinese medicines into powder to obtain the second traditional Chinese medicine combination for treating knee osteoarthritis of the present invention thing.

[0027] Use 500ml of 75% ethanol to reflux extract the second traditional Chinese medicine composition for 1 hour, recover the 75% ethanol to obtain a concentrated extract, then add 400ml of distilled water to dilute the obtained concentrated extract, and place the dilution on a water bath to evaporate residual ethanol, Then, the pH value of the diluent was adjusted to 9.0, then 15 g of ethyl paraben was added and dissolved, and the mixture solution was kept at 4 °C and placed for 12 h before suction filtration, and finally the filtrate was supplemented with distilled water to 500 ml.

[0028] 40g of urea and 10ml of triethanolamine were added to the above-mentioned 500ml of fi...

Embodiment 3

[0032] After grinding the six traditional Chinese medicines of 50g raw strychnids, 50g raw Chuanwu, 40g raw grass black, 45g frankincense, 60g myrrh and 35g angelica into powder to obtain the third traditional Chinese medicine combination for treating knee osteoarthritis of the present invention thing.

[0033] Use 500ml of 75% ethanol to reflux extract the third traditional Chinese medicine composition for 70 minutes, recover the ethanol to obtain a concentrated extract, then add 400ml of distilled water to dilute the resulting concentrated extract, and place the dilution on a water bath to evaporate residual ethanol, then The pH value of the diluent was adjusted to 9.0, then 20 g of ethyl paraben was added and dissolved, and the mixture solution was kept at 5 °C and placed for 13 h before suction filtration, and finally the obtained filtrate was supplemented with distilled water to 500 ml.

[0034] 45g of urea and 12ml of triethanolamine were added to the above-mentioned 500...

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PUM

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Abstract

A Chinese medicine composition for treating knee osteoarthritis and a preparation method thereof. The Chinese medicine composition comprises: by weight, 40 to 50 parts of Unprocessed Semen Strychni, 40 to 50 parts of Unprocessed Radix Aconiti, 30 to 40 parts of Unprocessed Radix Aconiti Kusnezoffii, 35 to 45 parts of Frankincense, 50 to 60 parts of Myrrh and 25 to 35 parts of Angelica sinensis. The Chinese medicine composition provided by the invention has favorable effects of activating blood circulation and arresting pain perception on knee osteoarthritis, and clinical data shows that a recurrence rate of knee osteoarthritis is very low after treatment utilizing the Chinese medicine composition.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating knee osteoarthritis and a preparation method thereof. Background technique [0002] The existing methods for the treatment of knee osteoarthritis include internal medicine, external medicine, surgery, acupuncture, massage, physiotherapy and rehabilitation. Oral administration of drugs has greater toxicity and side effects for patients, and surgery is usually more traumatic, while acupuncture, massage, and physiotherapy have the disadvantage of short duration of efficacy. SUMMARY OF THE INVENTION [0003] The purpose of the present invention is to provide a traditional Chinese medicine composition that can be effectively used for the treatment of knee osteoarthritis and a preparation method thereof. [0004] The Chinese medicine composition for treating knee osteoarthritis according to the present invention basically consists of the following components by weight: [00...

Claims

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Application Information

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IPC IPC(8): A61K36/714A61K9/06A61P19/02
Inventor 房敏龚利李建华孙武权
Owner YUEYANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL SHANGHAI UNIV OF CHINESE TRADITIONAL MEDICINE
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