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Compound pharmaceutical composition for treating upper airway cough syndrome and preparation method as well as application thereof

A syndrome and medicine technology, applied in the field of compound medicine, can solve the problems of inability to popularize and use, prescription correspondence and poor effect, and achieve the effect of complete curative effect, easy operation and short course of treatment

Active Publication Date: 2012-07-04
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are currently flaws in TCM syndrome differentiation. There are not many testimonies to treat from wind, from heat, or from phlegm, from blood stasis, from lung and spleen, and from lung and kidney. Wind-phlegm cough is more common, but the correspondence and effect of its prescriptions are poor. cannot be promoted

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A compound combination medicine for treating upper airway cough syndrome, which is composed of the following components in parts by weight: 10 parts of nepeta, 120 parts of ephedra, 50 parts of bellflower, 50 parts of shegan, 100 parts of mulberry bark, and 80 parts of almond , 10 parts of silkworm, 10 parts of Baiqian, 10 parts of Zhejiang fritillaria, 80 parts of polygala, 30 parts of raw licorice, 150 parts of clam shells, a total of twelve herbs.

[0019] Weigh the above twelve herbs in parts by weight, add 5 times the weight of water to soak for 60 minutes, decoct 3 times, each time for 2 hours, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a leaching solution with a relative density of 1.05 (60°C). paste, add ethanol until the alcohol content is 70%, let it stand for 24 hours, take the supernatant, recover the ethanol until it has no alcohol smell and concentrate to an appropriate amount, add water to 5000mL, stir well, sub-pa...

Embodiment 2

[0021] A compound combination medicine for treating upper airway cough syndrome, comprising the following components in parts by weight: Nepeta 100 parts, Ephedra 15 parts, Bellflower 10 parts, Shegan 10 parts, mulberry bark 50 parts, almond 110 parts, 100 parts of silkworm, 100 parts of Baiqian, 100 parts of Fritillaria fritillaria, 10 parts of polygala, 5 parts of raw licorice, and 100 parts of clam shells.

[0022] Weigh the above twelve herbs in parts by weight, add 8 times of water to soak for 30 minutes, decoct for 3 hours, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.15 (60°C), add ethanol until the alcohol content is 80 %, stand still for 24 hours, take the supernatant, recover ethanol until there is no alcohol smell and continue to concentrate to a relative density of about 1.30 (60°C), add appropriate amount of starch, vacuum dry, crush, granulate with 90% ethanol, dry, granulate, Tablets are obtained.

Embodiment 3

[0024] A compound combination medicine for treating upper airway cough syndrome, comprising the following components in parts by weight: 60 parts of Schizonepeta, 80 parts of Ephedra, 60 parts of Bellflower, 60 parts of Shegan, 10 parts of mulberry bark, 10 parts of almond, 80 parts of silkworm, 80 parts of Baiqian, 80 parts of Fritillaria fritillaria, 80 parts of polygala, 20 parts of raw licorice, and 80 parts of clam shells.

[0025] Weigh the above twelve herbs in parts by weight, add 15 times the amount of water to soak for 45 minutes, decoct twice for 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.10 (60°C) , add ethanol until the alcohol content is 60%, let it stand for 24 hours, take the supernatant, recover the ethanol until it has no alcohol smell and concentrate it to an appropriate amount, add water to 1000mL, stir well, subpackage, and circulate steam for 45 minutes to o...

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PUM

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Abstract

The invention discloses a compound pharmaceutical composition for treating upper airway cough syndrome and a preparation method as well as application thereof. The compound pharmaceutical composition comprises the following components in parts by weight: 10-100 parts of herba schizonepetae, 15-120 parts of ephedra, 10-60 parts of balloonflower, 10-60 parts of blackberrylily rhizome, 10-100 parts of mulberry bark, 10-110 parts of almond, 10-100 parts of stiff silkworm, 10-100 parts of cynanchum glaucescens, 10-100 parts of thunberg fritillary bulb, 10-100 parts of senega, 5-30 parts of raw licorice and 10-150 parts of clam shell. The compound pharmaceutical composition disclosed by the invention has the characteristics of good treatment effect, short course of treatment, thorough treatment effect, no side effect and the like. The mixtures, tablets, capsules, micropills and the like of the compound pharmaceutical composition are convenient to carry and take.

Description

technical field [0001] The invention relates to a compound combination medicine, in particular to a compound combination medicine for treating upper airway cough syndrome (abbreviated as UACS) made from decoction pieces of traditional Chinese medicine and a preparation method thereof. Background technique [0002] In recent years, the incidence of upper airway cough syndrome has been increasing year by year. According to foreign statistics, UACS accounts for 41% of the incidence of chronic cough in Europe and the United States, ranking first in the etiology of chronic cough. In China, UACS accounts for 70% to 95% of chronic cough in respiratory outpatient clinics. With social development, changes in living environment and lifestyle, UACS has become one of the main causes of chronic cough in my country, and there are obviously long disease duration and high incidence. , High rate of misdiagnosis. [0003] UACS is a syndrome characterized by cough as the main manifestation, wh...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8966A61P11/14A61K35/56A61K35/64A61K35/618
Inventor 史锁芳刘志辉
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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