Application of sweet almond oil in preparing medicament for treating myocardial ischemia reperfusion injury

A technology of reperfusion injury, sweet almond oil, applied in the field of plant materials, can solve problems such as side effects of the body

Inactive Publication Date: 2011-10-12
SHAANXI NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the use of these drugs will have certain side effects on the body to a certain extent.

Method used

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  • Application of sweet almond oil in preparing medicament for treating myocardial ischemia reperfusion injury
  • Application of sweet almond oil in preparing medicament for treating myocardial ischemia reperfusion injury
  • Application of sweet almond oil in preparing medicament for treating myocardial ischemia reperfusion injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Taking the production of 1000 soft capsule products of the present invention as an example, without adding any auxiliary materials, 800g sweet almond oil is directly made into soft capsules according to the conventional preparation process of soft capsules, and every grain weighs 0.8g.

[0014] Usage and dosage: Oral for adults, preventive dosage is 12 capsules each time, once a day, and therapeutic dosage is 12 capsules each time, twice a day.

[0015] In order to verify the beneficial effect of active ingredient sweet almond oil in treating myocardial ischemia-reperfusion injury, the inventor has carried out a drug effect test with sweet almond oil, and the specific test conditions are as follows:

[0016] Test drug: sweet almond oil, purchased from Guangzhou Lvxiangdao Natural Products Co., Ltd.

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Abstract

The invention provides an application of sweet almond oil in preparing a medicament for treating myocardial ischemia reperfusion injury. The medicament for preventing and treating myocardial ischemia reperfusion injury is prepared from sweet almond oil as an active component and is used in the form of soft capsules which are prepared directly from sweet almond oil by a conventional preparation method of soft capsules. Shown by drug effect tests, the sweet almond oil is capable of improving the hypoxia tolerance of the myocardial tissues of rats, enhancing the tolerance of the myocardial tissues to ischemia reperfusion myocardial injury, improving the antioxidant ability of the myocardial tissues of rats with ischemia reperfusion, and reducing the extent of injury to the myocardial tissuesof rats caused by ischemia reperfusion. The almond oil is a natural edible material with unsaturated fatty acid as a main active component, and can not generate toxic side effect on the body when taken in a certain dose range for a long term.

Description

technical field [0001] The invention belongs to the technical field of medical preparations containing raw materials or their reaction products with unknown structures, and specifically relates to materials derived from plants. Background technique [0002] Sweet almond oil is a vegetable oil extracted from the dried fruit of Prunus armeniaca L. in the family Rosaceae. Sweet almond oil is one of the most widely used vegetable oils. It is light yellow in color. It contains about 90% unsaturated fatty acids, including 60% oleic acid and 30% linoleic acid. It can reduce triglycerides in human blood and promote metabolism. , has a better effect on preventing cardiovascular and cerebrovascular diseases and protecting the liver. In addition, sweet almond oil also contains a small amount of vitamin E and other essential nutrients for the human body. Continuous consumption is not only beneficial to the development of cerebrovascular and intelligence, but also has special effects on...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61P9/00A61P9/10A61K131/00
Inventor 张志琪张婧张莉牟朝丽张清安
Owner SHAANXI NORMAL UNIV
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