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Application of epsilon-vinylphenine to preparation of cosmetics or medicaments for whitening skin and removing freckles

A technology of venifenin, whitening and freckle removal, applied in cosmetics, preparations for skin care, etc., can solve the problems of large side effects, stability of side effects, poor stability, etc., and achieve the effects of lightening pigmentation, no toxic side effects, and stable properties

Inactive Publication Date: 2012-01-18
TIANJIN KEMANSITE MEDICAL TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the current whitening products also inhibit the activity of tyrosinase, but these products limit their use due to side effects and stability issues
For example, hydroquinone has a good ability to inhibit tyrosinase activity, but its side effects are too large; kojic acid and its derivatives have strong whitening effect, but their stability is poor, and they are easy to decompose when exposed to light or heat.

Method used

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  • Application of epsilon-vinylphenine to preparation of cosmetics or medicaments for whitening skin and removing freckles
  • Application of epsilon-vinylphenine to preparation of cosmetics or medicaments for whitening skin and removing freckles
  • Application of epsilon-vinylphenine to preparation of cosmetics or medicaments for whitening skin and removing freckles

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1 Test method and whitening effect evaluation

[0015] 1 sample preparation

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PUM

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Abstract

The invention discloses application of epsilon-vinylphenine to the preparation of cosmetics or medicaments for whitening skin and removing freckles. A structural formula of the epsilon-vinylphenine is shown as a formula I. Experiments prove that the epsilon-vinylphenine can inhibit tyrosinase, resist radicals and ultraviolet rays, inhibit the generation of melanin effectively, fade chromatosis and delay the occurrence of age pigments and freckles, and has a skin whitening function. The epsilon-vinylphenine is from fruits, branches and leaves of natural vitis plants which have high safety for human bodies, and belongs to a natural product, does not contain chemical synthetics, does not have toxic or side effect, and is small in skin irritation and stable in properties.

Description

technical field [0001] The invention relates to a use of vinifenin. technical background [0002] The color of the skin depends on how much melanin is contained in the skin. Melanin is produced by melanocytes and is affected by various enzymes such as tyrosinase, dopachrome isomerase, and 5,6-dihydroxyindole-2-carboxylate oxidase during its formation. Among them, tyrosinase is the rate-limiting enzyme that determines the formation of melanin. Most of the current whitening products also inhibit the activity of tyrosinase, but these products limit their use due to problems such as side effects and stability. For example, hydroquinone is very good at inhibiting tyrosinase activity, but its side effects are too large; kojic acid and its derivatives have strong whitening effect, but their stability is poor, and they are easy to decompose when exposed to light or heat. Therefore, researchers turned their attention to natural products. Most natural products used in cosmetics ha...

Claims

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Application Information

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IPC IPC(8): A61K8/46A61Q19/02
Inventor 刘成航
Owner TIANJIN KEMANSITE MEDICAL TECH DEV
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