51results about How to "Inhibit tyrosinase" patented technology

The invention provides a full-function facial mask. The facial mask comprises the following components in percentage by mass: 0.01-2 percent of hyaluronic acid, 0.01-1 percent of reduced glutathione, 0.01-2 percent of L-vitamin C, 0.01-2 percent of tranexamic acid, 0.01-2 percent of liquiritigenin, 0.01-5 percent of vitamin E, 0.01-1 percent of EGF lyophilized powder, 0.01-2 percent of active peptide, 0.01-3 percent of SOD, 0.01-2 percent of arbutin, 0.1-2 percent of allantoin, 0.5-5 percent of glycerinum, 0.5-5 percent of propylene glycol and the balance of water, wherein the effective components are independently embedded with liposome or coated with nano-microcapsules before being mixed. The activated effective components of the facial mask are independently coated or embedded with transporters, and are delivered to the corium layer or the superficial corium layer by virtue of transportation of the transporters to achieve the effects of quadruple whitening, triple repairing and double moistening.

The invention discloses an active polypeptide and tyrosinase inhibitor composition for whitening and freckle removal. The composition comprises polypeptides with a melanogenesis inhibition function and/or polypeptides with a glycosylation resistance function, and other components with a tyrosinase activity inhibition function. The composition is capable of inhibiting melanogenesis, resisting glycosylation, eliminating saccharified dark yellow proteins and eliminating in-vivo free radicals, so as to achieve the aims of improving the skin types, whitening and removing freckles.

The invention provides a whitening composition, a preparation method thereof, a whitening essence containing the whitening composition and a preparation method of the whitening essence. The whiteningcomposition mainly contains six core components and auxiliary whitening components, wherein the six core components are as follows: a butterflybush flower extract, a sealwort extract, a biond magnoliaflower extract, a moutan bark extract, phloretin and 4-n-butyl resorcinol; and the auxiliary whitening components are as follows: nicotinamide, a vitamin C derivative, vitamin E and the like. The whitening essence contains the following components in percentage by weight: 2%-20% of the whitening composition, 5%-20% of a humectant, 1%-5% of a skin conditioner, 0.1%-5% of a solubilizer, 0.1%-1% ofa thickening agent, 0.02%-2% of a preservative and the balance of deionized water. The invention further provides the preparation method of the whitening composition and the preparation method of thewhitening essence containing the whitening composition. Experiments prove that an optimized formula of the whitening essence has very strong tyrosinase inhibitory activity and DPPH free radical scavenging activity, has very strong whitening and repairing functions in an ultraviolet radiation model of a guinea pig and has the effect remarkably better than that of a positive control drug.

The invention discloses whitening and freckle removing cream and a preparation method thereof. The whitening and freckle removing cream comprises diphenyl ketone-3, ethyl hexyl methoxycinnamate, niacinamide, a radix sophorae flavescentis extract, 4-butylresorcinol, VC ethyl ether, tranexamic acid and other raw materials. The whitening and freckle removing cream can inhibit tyrosinase, remove chloasma, resist free radicals, brighten skin color, be used safely without stimulation and is suitable for popularization and application.

The invention discloses a preparation method of azelaic acid supermolecules, which is characterized by comprising the following steps: mixing polyethylene glycol and propylene glycol to obtain a mixedsolvent; weighing and dissolving azelaic acid in the mixed solvent to form an azelaic acid solution; putting deionized water into a reaction container; heating to 95-100 DEG C, stirring at the rotating speed of 400 to 700r/min; dropwise adding the azelaic acid solution into deionized water at the speed of 0.5 to 1mL/min, controlling the dropwise adding temperature of the azelaic acid solution tobe 48 to 60 DEG C, and continuously stirring for 1.5 to 2.5 hours at the rotating speed of 400 to 700r/min after dropwise adding is finished, so as to obtain the azelaic acid supramolecule. The azelaic acid supermolecules are high in stability and good in solubility, can effectively solve the problems of poor stability and poor solubility of azelaic acid, are beneficial to storage, and can fully utilize azelaic acid resources to play a greater role in skin care and beauty.

The invention discloses a chaenomeles speciosa (Chaenomeles speciosa (Sweet) Nakai) plant extract, a cosmetic additive with effects of whitening skin, moisturizing and achieving antioxidant activity, as well as a combined application thereof in cosmetics. The chaenomeles speciosa extract refers to an ethanol extract of chaenomeles speciosa seeds, and the extract has good capability of scavenging radicals DPPH and is a good natural antioxidant. In the human skin protection aspect, the chaenomeles speciosa extract has excellent skin cosmetic application potentials with the effects of removing wrinkles, whitening and protecting sun. The traditional minority medicinal plant in China, namely the chaenomeles speciosa, is effectively utilized, and the chaenomeles speciosa extracts with extremely high skin cosmetic activity are obtained. The extracts can be used for manufacturing good antioxidants, has excellent effects of removing wrinkles, whitening and protecting sun and are good natural plant cosmetic raw materials.

The invention relates to a freckle-removing whitening cosmetic and a preparation method thereof. The freckle-removing whitening cosmetic comprises the following raw materials in parts by weight: 1-3 parts of hydroxyethyl acrylate-sodium acryloyldimethyl taurate copolymer, 5-20 parts of moisturizer, 5-15 parts of licorice extract, 4-7 parts of hydrogenated polyisobutene, 1-2 parts of sodium azone phosphate, 0.5-1.5 parts of cetearyl alcohol, 3-8 parts of kojic acid and kojic acid palmitate glyceryl cocoate and the balance of deionized water. The preparation method comprises the following steps: heating the deionized water and the moisturizer; and adding the hydroxyethyl acrylate-sodium acryloyldimethyl taurate copolymer, the hydrogenated polyisobutene and cetearyl alcohol and the licorice extract. In the freckle-removing whitening cosmetic and the preparation method thereof provided by the invention, the tyrosinase and the generation of melanin can be effectively inhibited to prevent new pigmentation, the non-uniform distribution and accumulation of melanocytes on the skin surface are reduced, and the aims of freckle removal and whitening are achieved while guaranteeing safety and avoiding toxic and side effects.

The invention belongs to the technical field of natural preservatives and particularly relates to a novel plant preparation with preservative effect as well as a preparation method and an applicationof the novel plant preparation. The plant preparation is prepared from raw materials in percentage by weight as follows: 30%-40% of cortex moutan extract, 30%-40% of white willow bark extract and 20%-30% of grapefruit extract. The novel plant preparation with the preservative effect has effects of bacteria resistance, inflammation diminishing and the like; after addition of the new plant preparation with the preservative effect, the shelf life of a skin care product can be prolonged, bacteria breeding is effectively inhibited, a preservative function is achieved, the moisturizing effect of theskin care product can be significant, and the skin care product is truly pure, natural, additive-free, green, safe and non-irritating to skin and is free of side and toxic effects.

The invention relates to the technical field of cosmetics, in particular to a composition having whitening efficacy and a preparation method and application of the composition. Based on dry weight ofmedicinal materials, the composition having whitening efficacy is prepared from the following raw materials in parts by weight of 1-20 parts of herba cistanches, 1-20 parts of poria cocos, 1-20 partsof radix astragali, 1-20 parts of radix angelica sinensis and 1-20 parts of ligusticum wallichii. The composition is in synergism of four components of a herba cistanch extract, a poria cocos extract,a radix astragali extract, a radix angelica sinensis extract and a ligusticum wallichii extract, and is united in synergistic effects, so that the superactive whitening effects of whitening skin andmuscle, reducing face stains and the like can be achieved. The preparation technology is mild in condition, high in extraction rate, free from special requirements on equipment, and low in preparationcost, and large-scale industrial production is facilitated.

The invention discloses a traditional Chinese medicine extract with herbs of red tassel flowers and application of the traditional Chinese medicine extract in preparing a skincare product. The addition amount of the traditional Chinese medicine extract with herbs of red tassel flowers in a skincare product is 0.5-10.0%, and the traditional Chinese medicine extract is made of the following raw material medicines in parts by weight: 20-60 parts of herbs of red tassel flowers, 10-20 parts of folium artemisiae argyi, 10-20 parts of rhizoma bletillae, 10-20 parts of astragalus roots and 10-20 partsof radix salviae miltiorrhizae. An extraction method of the traditional Chinese medicine extract with herbs of red tassel flowers comprises a supercritical CO2 extraction method and an ultrasonic extraction method, and the extract can be powder or an extraction liquid. The traditional Chinese medicine extract with herbs of red tassel flowers is added into the skincare product, on the basis of traditional Chinese medicine theories of China, herbs of red tassel flowers, folium artemisiae argyi, rhizoma bletillae, astragalus roots and radix salviae miltiorrhizae are effectively combined, traditional Chinese herbal medicine extracts are used as additives of beautifying skincare cosmetics, and the traditional Chinese medicine extract has the characteristics of being good in relieving effect, stable and long-lasting in medicine effect, mild in skin actions, small in irritation, high in security, remarkable in treatment effect, capable of treating both symptoms and root causes, and the like.

The invention relates to the field of skin health product processing, and in particular relates to a skin health product and a preparation method thereof. The skin health product comprises the following raw materials in parts by mass: 70-80 parts of solanesol of which the purity mass percentage is greater than 90%, 0.5-3 parts of tea leaf general flavones of which the purity mass percentage is greater than 90%, 0.5-3 parts of vitamin and 15-20 parts of beewax and/or glycerinum. Compared with a skin health product of the prior art, the skin health product provided by the invention has the function of inhibiting skin aging and senile plaque; just like chocolate in physical property, the skin health product can be molten at the body temperature, is remarkable in bioactivity in absorbing ultraviolet light, scavenging free radicals, inhibiting tyrosinase and inhibiting DNA damage, is very remarkable in effect in preventing aging, fading freckle and chloasma, removing senile plaque, moistening, blocking sun and softening cutin, and further has the effects of bacteriostasis and mosquito biting prevention.

The invention discloses a cosmetic ingredient with cuphea hossipifolia kunth extractives as raw materials for skin whitening, moisturizing and antioxidant activity and combination application in cosmetics. The cuphea hossipifolia kunth extractives are produced by drying cuphea hossipifolia kunth in the sun, smashing the cuphea hossipifolia kunth, soaking three times to four times at the room temperature, filtering, decompressing with ethnol liquid, concentrating into extract, adding defined amount of water, and extracting sequentially with petroleum ether and ethyl acetate to respectively obtain petroleum ether and ethyl acetate. A water layer flows through a D101 large hole resin column which is eluted by 25% methanol-water, 50% methanol-water, 75% methanol-water and methanol to obtain different distilling sections, the ethyl acetate is subjected with silica column chromatography to be eluted successively with petroleum ether, 25% acetone-petroleum ether, 50% acetone-petroleum ether, 75% acetone-petroleum ether, acetone and methanol to achieve different distilling sections, or ethanol of different concentration is used for extracting to obtain different extracts.

The invention discloses Pinus armandii Franch rosin extract, a cosmetic additive adopting the same for realizing skin whitening, moisturizing and antioxidant activity and an application of the Pinus armandii Franch rosin extract in cosmetics. The extract is ethanol extract of Pinus armandii Franch rosin, has good moistening and moisture preserving functions as well as a skin metabolism improvement function and a skin barrier function and can be taken as a collagen secretion promoting activator for skin cosmetics. The Pinus armandii Franch rosin extract breaks through limitation of a traditional utilization mode of Pinus armandii Franch rosin and is a good raw material for herbal cosmetics.