Composition with aging-delaying and skin-whitening effects and preparation method thereof

A technology for anti-aging and composition, which is applied in the field of anti-aging and whitening composition and its preparation, and in the fields of anti-aging and whitening composition and its preparation, which can solve the problem of unstable quality of medicinal materials, polysaccharide content of Polygonatum polysaccharides, etc. Oxidative activity differences and other issues, to achieve the effect of clearing DPPH, inhibiting tyrosinase, and delaying aging

Inactive Publication Date: 2019-03-29
BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, studies have shown that there are significant differences in the polysaccharide content and in vitro antioxidant activity of Polygonatum odoratum from different origins, and the quality of the medicinal material is extremely unstable.

Method used

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  • Composition with aging-delaying and skin-whitening effects and preparation method thereof
  • Composition with aging-delaying and skin-whitening effects and preparation method thereof
  • Composition with aging-delaying and skin-whitening effects and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Example 1 Composition with anti-aging and whitening effects and its preparation

[0036] Composition: Ganoderma lucidum and Polygonatum odoratum powder are prepared by two-way fermentation process, wherein Polygonatum odoratum is produced in Hubei, details are as follows:

[0037] (1) Preparation of medium: in parts by weight, 15 parts of peptone, 30 parts of glucose, 15 parts of sodium chloride, 0.6 part of calcium carbonate, and 60 parts of Polygonatum odoratum powder were dissolved in 3000 parts of distilled water, and the pH was adjusted to 7.2;

[0038] (2) Fermentation of Ganoderma lucidum: Ganoderma lucidum was subcultured for 4 generations in the slant medium, the culture temperature was 28°C, and the culture time was 10 days, and then inoculated in the liquid medium prepared in step (1), the inoculation quality of Ganoderma lucidum was the medium 6%, cultivated at 25°C for 138h, the dissolved oxygen content was 50%, and the rotational speed was 200rpm;

[0039] ...

Embodiment 2

[0040] Example 2 Composition and preparation thereof with anti-aging and whitening effects

[0041] Composition: Ganoderma lucidum and Polygonatum odoratum powder are prepared by two-way fermentation process, wherein Polygonatum odoratum is produced in Hubei, details are as follows:

[0042] (1) Preparation of medium: in parts by weight, 12 parts of peptone, 27 parts of glucose, 12 parts of sodium chloride, 0.55 parts of calcium carbonate, and 55 parts of Polygonatum odoratum powder were dissolved in 2800 parts of distilled water, and the pH was adjusted to 7.2;

[0043] (2) Fermentation of Ganoderma lucidum: Ganoderma lucidum was subcultured for 3 generations in the slant medium, the culture temperature was 25°C, and the culture time was 12 days, and then inoculated in the liquid medium prepared in step (1), the inoculation quality of Ganoderma lucidum was the medium 5%, cultivated at 22°C for 130h, the dissolved oxygen content was 45%, and the rotation speed was 180rpm;

[...

Embodiment 3

[0045] Example 3 Composition with anti-aging and whitening effects and its preparation

[0046] Composition: Ganoderma lucidum and Polygonatum odoratum powder are prepared by two-way fermentation process, wherein Polygonatum odoratum is produced in Hubei, details are as follows:

[0047] (1) Preparation of medium: in parts by weight, 18 parts of peptone, 33 parts of glucose, 18 parts of sodium chloride, 0.65 parts of calcium carbonate, and 65 parts of Polygonatum odoratum powder were dissolved in 3200 parts of distilled water, and the pH was adjusted to 7.4;

[0048] (2) Fermentation of Ganoderma lucidum: Ganoderma lucidum was subcultured for 5 generations in the slant medium, the culture temperature was 26°C, and the culture time was 8 days, then inoculated in the liquid medium prepared in step (1), the inoculation quality of Ganoderma lucidum was the medium 8%, cultivated at 28°C for 145h, the dissolved oxygen content was 55%, and the rotational speed was 250rpm;

[0049] (...

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Abstract

The present invention provides a composition with aging-delaying and skin-whitening effects. The composition is obtained by two-way fermentation of lucid ganoderma and radix polygonati officinalis powder, an addition of the radix polygonati officinalis powder can significantly improve yield of lucid ganoderma mycelia, the composition has significant effects on clearing DPPH, inhibiting tyrosinaseand increasing type I collagen and polysaccharide content, and besides, after the two-way fermentation, the product effectively reduces harmful substances in traditional Chinese medicines and effectively improves cell survival rate, fully demonstrating that the obtained lucid ganoderma and radix polygonati officinalis powder by the two-way fermentation has remarkable curative effects of delaying aging and whitening skin, and can be used as a functional substance for preparing related cosmetic raw materials.

Description

technical field [0001] The invention belongs to the field of bioengineering, and relates to a composition with anti-aging and whitening effects and a preparation method thereof, in particular to a composition with anti-aging and whitening effects prepared by using traditional Chinese medicine as a raw material through microbial bidirectional fermentation technology and its composition. Preparation. Background technique [0002] Removing freckles and nourishing the skin, whitening the skin, delaying aging, and maintaining youth forever are things people dream of, and people are always thinking of various ways to solve this problem. With age, the body's natural ability to resist free radicals continues to decline, cells continue to age, and problems such as rough skin and pigmentation become more prominent. China has a vast land and abundant resources, and has a wide variety of natural resources. In particular, traditional Chinese medicines have outstanding advantages in anti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9728A61K8/9794A61Q19/02A61Q19/08
CPCA61K2800/782A61K2800/85A61Q19/02A61Q19/08A61K8/9728A61K8/9794
Inventor 李丽董银卯孟宏何一凡吴晗
Owner BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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