The invention discloses a fructus alpiniae oxyphyllae and compatible
lindera aggregata extract for treating diabetes. The extract mainly comprises extract of
petroleum ether part of fructus alpiniae oxyphyllae and compatible
lindera aggregata extract, wherein the fructus alpiniae oxyphyllae and
lindera aggregata are decocted with water according to the proportion of 1: 1 in a conventional way for three times, and concentrated solution is collected, so that dry extract can be obtained. The method comprises the steps of
grinding, screening, carrying out
reflux extraction, filtering, adding a
solvent for extracting, recovering the
solvent, carrying out ultrasonic extraction on
lindera aggregata extract solution and preparing. According to the fructus alpiniae oxyphyllae and compatible
lindera aggregata extract for treating the diabetes, and a preparation method of the extract provided by the invention, the harm of the diabetes to a patient is improved by the
petroleum ether part of fructus alpiniae oxyphyllae extract,
diabetic nephropathy (DN) can be treated by the extract, and
kidney function decrease can be delayed; the fructus alpiniae oxyphyllae and compatible
lindera aggregata extract is capable of promoting down regulation of the p27kip1
protein expression, has the functions of relieving
kidney hypertrophia, reducing
proteinuria and protecting the functions of the
kidney, can effectively prevent diabetes complications, and is good in
diabetes treatment effect.