Chinese medicinal composition for treating epigastric pain and preparation method thereof

A composition and a technique for epigastric pain, which are applied in the field of traditional Chinese medicine compositions and their preparations, can solve the problems of application limitation, high recurrence rate of ulcer disease, and reduce recurrence rate, and achieve the improvement of Helicobacter pylori, elimination of gastric mucosal inflammation, and promotion of gastric mucosal inflammation. Ulcer healing effect

Active Publication Date: 2012-03-14
吉林华康药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the western medicines with better clinical efficacy in the treatment of peptic ulcer at home and abroad are H2 receptor blockers; Ulcer cure rate can reach more than 66-90%. However, due to the high recurrence rate of western medicine treatment of ulcer disease, and the side effects on the liver, hematopoietic system and central nervous system, some western medicines also cause gastric mucosal hyperplasia and other reactions, so its application is limited. Restrictions; chronic gastritis, there is no specific Western medicine; since Warren first isolated Helicobacter pylori (HP) from human gastric mucosa in 1982, modern medicine has deeply studied the close relationship between HP an

Method used

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  • Chinese medicinal composition for treating epigastric pain and preparation method thereof
  • Chinese medicinal composition for treating epigastric pain and preparation method thereof
  • Chinese medicinal composition for treating epigastric pain and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Coptidis 600g, Baishao 600g, Burnet 200g, Baiji 300g, Gallus gallus 200g.

[0016] Coptis chinensis and 5 / 6 prescription amount of white peony are extracted twice with water, and the rest of the medicinal materials are finely powdered, the first time is added to boil for 2.0 hours, the second time is added to boil for 2.5 hours, concentrated under reduced pressure, vacuum dried, and finally the extract powder and medicinal materials powder mix.

Embodiment 2

[0018] Coptidis 625g, Baishao 625g, Burnet 208g, Baiji 313g, Gallus gallis 208g.

[0019] Coptis chinensis and 5 / 6 prescription amount of white peony are extracted twice with water, and the remaining medicines are finely powdered, boiled for 2.5 hours in water for the first time, boiled in water for 2.0 hours in the second time, concentrated under reduced pressure, and dried in vacuum. Finally, extract powder and medicinal materials powder mix.

[0020] The active ingredient that above-mentioned prescription quantity is made adds the conventional adjuvant of preparation micropill, makes 1000g micropill, 104 times of equivalent former decoction prescription quantity.

Embodiment 3

[0022] Coptidis 650g, Baishao 650g, Burnet 216g, Baiji 326g, Gallus gallis 216g.

[0023] Coptis chinensis and 5 / 6 prescription amount of white peony are extracted twice with water, and the rest of the medicinal materials are finely powdered, the first time is added to boil for 3.0 hours, the second time is added to boil for 1.5 hours, concentrated under reduced pressure, vacuum dried, and finally the extract powder and medicinal materials powder mix.

[0024] Further verify the present invention by main pharmacodynamic test below.

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Abstract

The invention relates to a Chinese medicinal composition for treating epigastric pain and a preparation method thereof, belonging to a Chinese medicinal composition and a preparation method thereof. The Chinese medicinal composition comprises the following ingredients: 600-650 weight portions of coptis root, 600-650 weight portions of white paeony root, 200-216 weight portions of garden burnet, 300-326 weight portions of rhizoma bletillae, 200-216 weight portions of Corium stomachichum galli. The Chinese medicinal composition is prepared by the following steps: extracting coptis root and 5/6 prescribed amount of white paeony root with water, crushing other medicinal materials into fine powder, adding water for decoction for 2.0-3.0 h in the first time, adding water for decoction for 1.5-2.5 h in the second time, carrying out concentration under reduced pressure, carrying out vacuum drying, and finally mixing the extract powder and medicinal material powder. The Chinese medicinal composition used for treating epigastric pain with fire stagnation has good curative effect, and has the characteristics of resisting helicobacter pylori, promoting ulcer healing, eliminating esogastritis, and reducing recurrence, and the usage of the Chinese medicinal composition is safe.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, which are used for treating epigastric pain and fire stagnation syndrome. Background technique [0002] Epigastric pain is a common and recurrent chronic disease with frequent pain in the upper abdominal epigastric region; it includes gastric and duodenal ulcers in modern medicine, acute and chronic gastritis, gastric neurosis, gastroptosis , gastric cancer, etc. Among them, epigastric pain caused by peptic ulcer and chronic gastritis is more common. The TCM treatment of epigastric pain can be summarized as (1) syndrome differentiation and treatment: addition and subtraction according to the pathogenesis; (2) fixed classification and fixed prescription method: that is, one side is fixed for each syndrome type, and no addition or subtraction is performed; (3) agreement Prescriptions, secret recipes, and special prescriptions: reflect the unique experie...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P1/04A61P31/04A61K35/37A61K35/57
Inventor 胡军会朱继忠刘传贵金立群王文杰潘洪波
Owner 吉林华康药业股份有限公司
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