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Medicine for treating depression, and preparation method and application thereof

A depression and drug technology, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve problems such as strong side effects, achieve weight gain, reverse the reduction of sugar water consumption, and shorten immobility time Effect

Inactive Publication Date: 2012-04-18
NANJING HAIYUAN CHINESE HERBAL PIECES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] In view of the high incidence of depression and the strong side effects of current clinically used drugs for treatment of depression, Chinese medicine is of great significance for treating depression. traditional Chinese medicine

Method used

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  • Medicine for treating depression, and preparation method and application thereof
  • Medicine for treating depression, and preparation method and application thereof
  • Medicine for treating depression, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: the preparation of medicament oral liquid of the present invention (named as Shun Xin Jie Yu oral liquid)

[0032] (1) Take each crude drug (Chinese herbal decoction pieces after Chinese medicine processing) according to the following proportioning by weight: Bupleurum 6g, Salvia miltiorrhiza 30g, Shichangpu 6g, Polygala 6g, Curcuma 10g, Coptis 3g, keel 10g, oyster 10g , lapis lazuli 10g.

[0033] (2) Bupleurum bupleuri, Salvia miltiorrhiza, Shichangpu, polygala, turmeric, and Coptis chinensis in the above weight ratio are made into coarse powder, and 1 times the amount of 85% ethanol is used to moisten for 2 hours, packed into a column, and packed with 85% ethanol after packing. Remove air bubbles with % ethanol, infiltrate for 24 hours, then percolate with 20 times the amount of 85% ethanol, percolation flow rate 5mL min -1 kg -1 , combined leachate, concentrated under reduced pressure to a relative density of 1.3 at 65 ° C, and dried to obtain dry ext...

Embodiment 2

[0036] Embodiment 2: the preparation of medicament oral liquid of the present invention

[0037] (1) Take each crude drug (Chinese herbal decoction pieces after Chinese medicine processing) according to the following proportioning by weight: Bupleurum 4g, Salvia miltiorrhiza 40g, Shichangpu 4g, Polygala 8g, Curcuma 5g, Coptis 4g, keel 5g, oyster 15g , lapis lazuli 5g.

[0038] (2) Bupleurum bupleuri, Salvia miltiorrhiza, Shichangpu, polygala, turmeric, and Coptis chinensis in the above weight ratio are made into coarse powder, and 1 times the amount of 85% ethanol is used to moisten for 2 hours, packed into a column, and packed with 85% ethanol after packing. Remove air bubbles with % ethanol, infiltrate for 24 hours, then percolate with 20 times the amount of 85% ethanol, percolation flow rate 5mL min -1 kg -1 , combined leachate, concentrated under reduced pressure to a relative density of 1.2 at 65 ° C, and dried to obtain dry extract powder.

[0039] (3) Fly the keel, o...

Embodiment 3

[0041] Embodiment 3: the preparation of medicine capsule of the present invention, its step is:

[0042] (1) Take each crude drug (Chinese herbal decoction pieces after Chinese medicine processing) according to the following proportioning by weight: Bupleurum 8g, Salvia miltiorrhiza 20g, Shichangpu 8g, Polygala 4g, Curcuma 15g, Coptis 2g, keel 15g, oyster 5g , lapis lazuli 15g.

[0043] (2) Bupleurum bupleuri, Salvia miltiorrhiza, Shichangpu, polygala, turmeric, and Coptis chinensis in the above weight ratio are made into coarse powder, and 1 times the amount of 85% ethanol is used to moisten for 2 hours, packed into a column, and packed with 85% ethanol after packing. Remove air bubbles with % ethanol, infiltrate for 24 hours, then percolate with 20 times the amount of 85% ethanol, percolation flow rate 5mL min -1 kg -1 , combined leachate, concentrated under reduced pressure to a relative density of 1.3 at 65 ° C, and dried to obtain dry extract powder.

[0044] (3) Fly the...

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Abstract

The invention discloses a medicine for treating depression, and a preparation method thereof. The medicine is prepared from bupleurum chinense, root of red-rooted salvia, acorus gramineus, thinleaf milkwort rootbark, zedoary, coptis chinensis, dragon bone, oyster, and chlorite schist in a certain weight part proportion; bupleurum chinense, root of red-rooted salvia, acorus gramineus, thinleaf milkwort rootbark, zedoary and coptis chinensis are extracted by a percolation method, dragon bone, oyster, and chlorite schist are extracted by a levigation method, then extracts are mixed, and mixed extracts and auxiliary materials are mixed to be prepared into any common oral formulation. The medicine has the effects of soothing the liver and regulating vital energy, activating blood and dissolving stasis, tranquilizing the mind, reducing phlegm and purging fire and the like, is used for treating liver qi stagnation, vexation and sleeplessness and other symptoms, and is also used for treating depression.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a medicine for treating depression made from traditional Chinese medicines, a preparation method and an application thereof. Background technique [0002] In modern society, with the acceleration of people's pace of life and the increase of work pressure, the incidence of mental disorders is increasing at an alarming rate. Depression is one of the most serious mental disorders. The main manifestations are depression, loss of interest, pessimism, slow thinking, lack of initiative, self-blame, poor diet and sleep, worry that you have various diseases, and feel multiple discomforts throughout the body. In severe cases, suicidal thoughts and behaviors may occur . According to statistics, the suicide rate of patients with depression is 20 times higher than that of the general population; among the suicide population, nearly 80% of them suffer from de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P25/20A61P25/24A61K33/26A61K35/02A61K35/56A61K35/618
Inventor 蔡宝昌顾锡镇何媛媛李兴尚李鹏秦昆明汪斌
Owner NANJING HAIYUAN CHINESE HERBAL PIECES CO LTD
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