Chinese medicinal composition for treating infectious bronchitis and its preparation method

A technology for bronchitis and chicken infectivity, applied in the field of traditional Chinese medicine compositions, can solve the problems of low cross-immunity level, unsatisfactory effect, IBV mutation, etc., and achieves the effects of no toxic side effects, significant and reliable curative effect, and improvement of pathological damage.

Inactive Publication Date: 2012-06-13
CHONGQING ACAD OF ANIMAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the large number of IBV serotypes and the low level of cross-immunity among the strains, it is necessary to use a large-scale and high-intensity vaccine to effectively prevent it. The continuous use of vaccines, especially attenuated vaccines, can easily cause IBV to mutate and lead to super-virulent Strain formation, induced IB
There is no specific drug treatment for chickens infected with IB. Nowadays, Western medicine is often used for symptomatic treatment, but the effect is often unsatisfactory, resulting in serious drug residues. Therefore, it is of great clinical significance to find new drugs to treat IB.

Method used

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  • Chinese medicinal composition for treating infectious bronchitis and its preparation method
  • Chinese medicinal composition for treating infectious bronchitis and its preparation method
  • Chinese medicinal composition for treating infectious bronchitis and its preparation method

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preparation example Construction

[0031] The preparation method of the present invention also adds chitosan in the cooling process of the concentrated extract, and chitosan can remove many unstable particles such as protein, manganese liquid, gum, saddle, etc., and the concentrated extract can The active ingredients are retained to a large extent, safe and non-toxic.

[0032] Other advantages, objects and features of the present invention will be set forth in the following description to some extent, and to some extent, will be obvious to those skilled in the art based on the investigation and research below, or can be obtained from It is taught in the practice of the present invention.

[0033]

Embodiment 1

[0035] 1 Preparation of Chinese medicine composition preparation for treating chicken infectious bronchitis

[0036] (1) Weigh 10Kg of the traditional Chinese medicine composition for treating chicken infectious bronchitis. The above 10 Kg traditional Chinese medicine composition consists of the following components in parts by weight: 20 parts of Shandougen, 15 parts of Shegan, 15 parts of Anemarrhena, 15 parts of gypsum 15 parts of ephedra, 10 parts of almond and 10 parts of licorice; the Chinese medicine composition is crushed and put into the traditional Chinese medicine extraction equipment together with 80kg of water and extracted by steam heating, and the temperature of the heated material is controlled between 75-77 °C , after refluxing for 1h, the material is filtered to obtain the extract and dregs;

[0037] (2) According to the method described in step (1), the filtered medicinal residues are extracted twice, and the extracts produced by the two extractions are resp...

Embodiment 2

[0050] 1 The preparation of the Chinese medicine composition preparation for the treatment of chicken infectious bronchitis

[0051] (1) Weigh 10Kg of the traditional Chinese medicine composition for the treatment of chicken infectious bronchitis. The above 10 Kg Chinese medicine composition is composed of the following components in parts by weight: 22 parts of Shandougen, 14 parts of Shegan, 14 parts of Anemarrhena, 14 parts of gypsum 14 parts of ephedra, 11 parts of almonds and 11 parts of licorice; the above medicinal materials are crushed and put into traditional Chinese medicine extraction equipment together with 90kg of water and extracted by steam heating, and the temperature of the heated material is controlled between 77-80 °C. After refluxing for 1h, the material is filtered to obtain the extract and medicinal residues;

[0052] (2) According to the method described in step (1), the filtered medicinal residues are extracted twice, and the extracts produced by the tw...

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Abstract

The invention discloses a Chinese medicinal composition for treating infectious bronchitis and its preparation method. The Chinese medicinal composition is prepared from vietnamese sophora roots, Rhizoma Belamcandae, Rhizoma Anemarrhenae, gypsum, Herbal Ephedrae, almonds and Radix glycyrrhizae in certain proportion. With simple formula, low cost and stable quality, the Chinese medicinal composition can be used to effectively treat infectious bronchitis. Compared with the control group of Maxingshigan decoction, the prescription of the composition has mortality decreased by 6.9%-24%, a cure rate enhanced by 6%-26.7%, and an effective rate increased by 6.9%-24%; and compared with an infected control group, the mortality is reduced by 18.2%-35.3%. Through comprehensive judgment on the characteristic lesion scores of tracheas and kidneys, the composition has good improving effects on pathological damages in chickens infected with IBV (infectiousbronchitis virus), and it not only has definite curative effects, but also has no toxic or side effect and drug residue. While improving breeding benefits, the composition also avoids causing harm to bodies of chicken eaters. Prepared by the steps of raw material grinding, extraction, and extraction solution concentration, the Chinese medicinal composition of the invention not only has stable product quality, but also has the advantages of simple process, easily controllable conditions, no discharge of ''three wastes'' during production, and environment friendliness, thus being very suitable for industrial production.

Description

Technical field [0001] The invention involves a Chinese medicine composition, which specializes in a Chinese medicine composition and preparation method that treats chicken infectious bronchitis. Background technique [0002] Infectious bronchitis (IB) is an acute, high contact infectious disease caused by the infectious bronchitis virus (IBV). Once the disease is infected, it is difficult Etexture is one of the severe infectious diseases that seriously endanger the development of the chicken industry in my country.At present, IB mainly relies on vaccination to prevent it, while strengthening breeding management to avoid the occurrence of the disease.Due to the numerous serum types of IBV, the cross -immune level between the strains is low, and the large -scale and high -intensity use of vaccines can be effectively prevented. The continuous use of vaccines, especially weak poisonous seedlings, can easily cause IBV mutations, resulting in super strong poisonous poisonThe formation...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K47/36A61P31/14A61P11/00
Inventor 曹国文陈春林郑华李成洪翟少钦付利芝
Owner CHONGQING ACAD OF ANIMAL SCI
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