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Chinese herbal preparation for treating vaginitis and preparation method thereof

A technology of traditional Chinese medicine preparations and vaginitis, which is applied in the direction of anti-inflammatory agents, medical formulas, non-central analgesics, etc., and can solve problems such as difficult to completely cure diseases, inconvenient use, and large loss of liquid medicine

Active Publication Date: 2013-08-28
陕西步长高新制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During the actual experimental research, we found that the single herb of Hawthorn has unexpected therapeutic effects on vaginitis caused by various reasons. Therefore, we applied for the application number 03139655.0 on June 26, 2003 The invention patent was obtained after that, and the patent document is mainly protected from the aspects of prescription ratio and lotion. However, because the vaginal lotion formulation itself belongs to local application, it is inconvenient to use and the loss of liquid medicine is large, so it cannot be maintained. Shortcomings such as long-term effect and difficult to completely cure the disease, which lead to its influence on the promotion and use of the drug itself to a certain extent

Method used

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  • Chinese herbal preparation for treating vaginitis and preparation method thereof
  • Chinese herbal preparation for treating vaginitis and preparation method thereof
  • Chinese herbal preparation for treating vaginitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0089] (1) Take 1170 g of hawthorn cores, crush them, add water with a weight ratio of 8 times that of the medicinal materials, and soak in water with a pH value of 4.5 for 30 minutes, heat and reflux extraction for 3 times, each time for 1 hour, filter, and combine the filtrates for future use;

[0090] (2) the filtrate in the above-mentioned (1) is concentrated into a concentration that every ml contains the aqueous solution of 0.5g of hawthorn nuclear crude drug amount, passes through the D-101 macroporous adsorption resin that has been processed, washes with water first, and then uses a concentration of Eluted with 60% ethanol, collected the alcohol lotion, recovered the ethanol under reduced pressure, concentrated and dried, and pulverized into a dry cream powder, added starch, mixed evenly, packed into hard capsules, and made into 1000 capsules.

Embodiment 2

[0092] (1) Take 1170 g of hawthorn core, crush it, add water with a weight ratio of 6 times that of the medicinal material, and soak in water with a pH value of 3.0 for 20 minutes, heat and reflux for extraction twice, each time for 1.5 hours, filter, and combine the filtrate for use;

[0093] (2) the filtrate in the above-mentioned (1) is concentrated into a concentration that every ml contains the aqueous solution of 0.6g of hawthorn nuclear crude drug, through the AB-8 macroporous adsorption resin that has been processed, first washed with water, and then with a concentration of Elute with 50% ethanol, collect the alcohol lotion, recover the ethanol under reduced pressure, concentrate and dry, grind into a dry cream powder, add starch, mix well, pack into hard capsules, and make 1000 capsules.

Embodiment 3

[0095] (1) Take 1170 g of hawthorn core, grind it, add water with a weight ratio of 10 times that of the medicinal material and a pH value of 5.5, soak for 40 minutes, heat and reflux for extraction for 3 times, each time for 2 hours, filter, and combine the filtrate for future use;

[0096] (2) the filtrate in the above-mentioned (1) is concentrated into a concentration that every ml contains the aqueous solution of 0.2g of hawthorn nuclear crude drug amount, passes through the HP-20 macroporous adsorption resin that has been processed, washes with water first, and then uses a concentration of Elute with 70% ethanol, collect the alcohol lotion, recover the ethanol under reduced pressure, concentrate and dry, grind into a dry cream powder, add starch, mix well, pack into hard capsules, and make 1000 capsules.

[0097] The macroporous adsorption resin in the above method can be selected from medium polarity or non-polarity adsorption resin.

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Abstract

The invention relates to a Chinese herbal preparation for treating vaginitis and a preparation method thereof. The Chinese herbal preparation for treating the vaginitis is prepared by that the hawthorn seed serves as a raw material, and the hawthorn seed and pharmaceutically-acceptable auxiliary materials are mixed after the hawthorn seed is extracted and refined according to a certain technology. The Chinese herbal preparation disclosed by the invention has a simple and feasible preparation technology and obvious pharmacology and drug efficacy action and is safe and effective.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating vaginitis and a preparation method thereof, belonging to the technical field of medical preparations. Background technique [0002] Vaginitis is a common and frequently-occurring disease in women's reproductive system inflammation. The main symptoms are increased leukorrhea, pruritus vulvae or accompanied by scorching heat in the vulva, which belongs to the scope of leukorrhea and pruritus vulvae in the motherland's medicine. The etiology is mostly negligence of hygiene, infection of vaginal worms, or damp-heat betting, accumulation of stagnation and worms, or spleen deficiency and damp resistance, dampness and turbidity overflowing the lower energizer, hurting the two veins of the kidney, or liver and kidney yin deficiency, dryness and wind, or Stagnation of heart and liver qi, long-term fire of stagnation caused by disturbing the meridians. Modern Western medicine belie...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/734A61P15/02A61P31/04A61P31/10A61P33/02A61P29/00A61K131/00
Inventor 赵涛卢露谢伟
Owner 陕西步长高新制药有限公司
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