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Novel purpose of eucommia chemical components as blood vessel protective agent

A vascular protective agent and application technology, which is applied in the new application field of Eucommia ulmoides chemical constituents as a vascular protective agent, which can solve problems such as abnormal vascular function and damage to the vascular system.

Active Publication Date: 2012-07-11
JIANGXI POZIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The human vascular system has its own normal metabolic balance function, but abnormal vascular function can cause damage to the vascular system

Method used

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  • Novel purpose of eucommia chemical components as blood vessel protective agent
  • Novel purpose of eucommia chemical components as blood vessel protective agent
  • Novel purpose of eucommia chemical components as blood vessel protective agent

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Embodiment Construction

[0056] Various aspects and features of the present invention are further described below.

[0057]All the documents cited in the present invention are incorporated herein by reference in their entirety, and if the meaning expressed in these documents is inconsistent with the present invention, the expression of the present invention shall prevail. In addition, various terms and phrases used in the present invention have common meanings known to those skilled in the art. Even so, the present invention still hopes to make a more detailed description and explanation of these terms and phrases here. The terms and phrases mentioned are as follows: If there is any inconsistency with the known meaning, the meaning expressed in the present invention shall prevail.

[0058] As described herein, the term "Eucommia" complies with the provisions under the corresponding item in the 2005 edition of "Pharmacopoeia of the People's Republic of China".

[0059] The term "about" used herein, su...

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PUM

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Abstract

The invention relates to a novel purpose of eucommia chemical components as blood vessel protective agents. Specifically, the invention relates to a purpose of eucommia or eucommia extracts in preparing medicines used as blood vessel protective agents and / or antihypertensive agents, or in preparing medicines used for treating and / or preventing vascular proliferation diseases. The eucommia extracts comprise at least one component selected from the following: geniposide, wogonin, Qianye extract A, alpha-oxygen-beta-D-glucopyranoside-4,2', 4'-trihydroxyl dihydrochalcone, and betulic acid. According to the invention, the 5 chemical components or the eucommia extracts comprising the 5 chemical components can be used as effective blood vessel protective agents and / or antihypertensive agents, and can be used for treating and / or preventing vascular proliferation diseases.

Description

technical field [0001] The present invention relates to the new application of several chemical components in Eucommia ulmoides, in particular, chibain A, wogonin, α-oxygen-β-D-glucopyranosyl-4,2′,4 in eucommia ulmoides Pharmaceutical use of '-trihydroxydihydrochalcone, betulinic acid, and geniposide as vascular protective agents. Background technique [0002] The human vascular system has its own normal metabolic balance function, but abnormal vascular function can cause damage to the vascular system. For example, the proliferation of vascular smooth muscle cells is the pathological basis of atherosclerotic plaque formation and restenosis after coronary angioplasty; the increase of calcium ion concentration in smooth muscle cells can cause vasoconstriction, and abnormal vasomotor function can lead to hypertension happened. Some vascular protective agents can reduce blood pressure by antagonizing the increase of calcium ion concentration in vascular smooth muscle cells cau...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/46A61P3/10A61P7/10A61P9/00A61P9/10A61P9/12A61P9/14A61P13/12A61P25/04A61P25/06
Inventor 高秀梅王虹苏艳芳樊官伟刘二伟王跃飞张伯礼
Owner JIANGXI POZIN PHARMA
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