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Procyanidine soft capsule

A technology of proanthocyanidins and soft capsules, which is applied in the fields of application, food preparation, food science, etc., can solve the problems of large dosage and poor dosage compliance, and achieve the effects of increasing the amount of active ingredients, lowering production costs, and improving market competitiveness.

Inactive Publication Date: 2012-07-25
ZHEJIANG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There are many types of proanthocyanidin products in the market at present, but the dosage is relatively large. It takes 4 to 9 capsules per day and needs to be taken in 2 to 3 times. For middle-aged and elderly people, the compliance of taking is poor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] (1) Weigh 180g of proanthocyanidin mixture, 305g of soybean oil, 2.5g of beeswax, and 12.5g of concentrated soybean phospholipid, heat the vegetable oil to 80°C, add beeswax, stir until the beeswax is completely melted, cool down to 50°C, add phospholipid, stir, mix Uniformly; then add the proanthocyanidin mixture, mix, stir evenly, grind three times through a colloid mill, vacuum degas (vacuum degree -0.06~-0.08MPa), and make the contents of the soft sac, and set aside.

[0024] (2) Take 150g of gelatin, 75g of glycerin, and 135g of water, heat the water to 50°C, turn on the mixer, add glycerin and stir evenly, then add gelatin to soak to make the gelatin fully expand, heat to 80°C, keep warm for 2 hours, wait for glue The solution is completely melted, mixed uniformly, then stopped stirring, vacuumized (vacuum degree -0.06~-0.08MPa), removed the air bubbles in the glue solution, and filtered through a 100-mesh sieve to obtain the soft capsule capsule skin solution, whi...

Embodiment 2

[0027] (1) Weigh 150g of the proanthocyanidin mixture, 332.5g of soybean oil, 7.5g of beeswax, and 10g of concentrated soybean phospholipids, and prepare the contents of the soft capsule according to the step (1) of Example 1.

[0028](2) Take 118g gelatin, 54.2g glycerin, 18g sorbitol, 3g mannitol, 0.20g ethylparaben and 106.6g water, heat the water to 45°C, turn on the stirrer, add glycerin, sorbitol, mannitol , Ethylparaben and stir evenly, then add gelatin to soak, make the gelatin fully expand, heat to 70°C, keep warm for 2 hours, wait until the glue is completely melted, stop stirring after mixing uniformly, vacuumize (vacuum degree -0.06~-0.08 MPa), get rid of the air bubbles in the glue, and filter through a 100-mesh sieve to obtain the skin liquid of the soft capsule, inject it into an insulated bucket (60° C.), and let it stand for 8 hours. ,

[0029] (3) Fill soft capsules according to the method of Example 1 step (3), the difference is that the mass ratio of the c...

Embodiment 3

[0031] (1) Take by weighing 200g of the proanthocyanidin mixture, 275g of soybean oil, 5g of beeswax, and 20g of concentrated soybean phospholipids, and prepare the contents of the soft capsule according to the step (1) of Example 1.

[0032] (2) Take 152g of gelatin, 76g of glycerin, 30.4g of sorbitol, 4.6g of mannitol, and 137g of water, heat the water to 50°C, turn on the mixer, add glycerin, sorbitol, and mannitol and stir evenly, then add gelatin to soak, so that The gelatin is fully expanded, heated to 80°C, and kept warm for 2 hours. After the glue is completely melted, stop stirring after mixing uniformly, vacuumize (vacuum degree -0.06~-0.08MPa), remove the air bubbles in the glue, and filter through a 100-mesh sieve. Obtain the capsule skin fluid of the soft capsule, inject in the heat preservation barrel (60 ℃), leave standstill for 4 hours.

[0033] (3) Fill soft capsules according to the method of Example 1 step (3), the difference is that the mass ratio of the ca...

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Abstract

The invention provides a procyanidine soft capsule, which comprises contents consisting of procyanidine, plant oil, beewax and phospholipid according to mass percentage: 10 percent to 60 percent of procyanidine mixtures, 35 percent to 87.5 percent of plant oil, 0.5 percent to 2.5 percent of beewax and 1 percent to 5 percent of phospholipid. The procyanidine soft capsule can be prepared from the procyanidine mixture, the plant oil, the beewax, the phospholipid and other human body acceptable medical auxiliary ingredients through a pressing method. The procyanidine soft capsule provided by the invention has the advantages that the production cost is low, and the production process is simple, convenient and advanced. The appearance of the procyanidine soft capsule is attractive, the carrying is convenient, the dosage is small, one capsule is taken in one day, and the taking compliance is good. The procyanidine soft capsule is particularly suitable for middle-aged people and old people and has good anti-oxidation health-care effects.

Description

(1) Technical field [0001] The invention relates to the field of health food, in particular to a proanthocyanidin soft capsule (2) Background technology [0002] Proanthocyanidins (Oligomeric Proantho Cyanidins, OPC) is a kind of polyphenol bioflavonoids, which is composed of different amounts of catechin or epicatechin. It is a mixture of polyphenols. Proanthocyanidins are mainly extracted and refined from plants. Studies have shown that the content of proanthocyanidins in grape seeds and pine bark is the highest. So far, 16 proanthocyanidins have been isolated and identified from grape seeds and skins, including 8 dimers, 4 trimers, and others as tetramers, pentamers and hexamers. Studies have shown that , the ability of proanthocyanidins in the body to resist oxidation and scavenge free radicals is V E 50 times of Vc, 20 times of Vc. [0003] After a person reaches a certain age, the amount of antioxidant substances naturally produced in the body will decrease year by ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/29A23L33/00
Inventor 单伟光唐岚黄金龙殷之武施存元于海宁
Owner ZHEJIANG UNIV OF TECH
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