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Traditional Chinese medicine composition capable of inhibiting activity of 5alpha-reductase and application of traditional Chinese medicine composition to hair loss prevention cosmetics

A composition and cosmetic technology, applied in the field of compound traditional Chinese medicine compositions, can solve the problems of large side effects, large irritation of western medicine ingredients, etc., and achieve strong inhibition of 5α-reductase activity and excellent anti-seborrheic alopecia function. Effect

Inactive Publication Date: 2012-10-03
龚盛昭
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the ingredients of western medicine are highly irritating and have great side effects, so the development of natural 5α-reductase has been paid more and more attention. The invention patent CN201010100520.1 has announced the use of cinnamon oil in the preparation of 5α-reductase inhibitor drugs

Method used

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  • Traditional Chinese medicine composition capable of inhibiting activity of 5alpha-reductase and application of traditional Chinese medicine composition to hair loss prevention cosmetics
  • Traditional Chinese medicine composition capable of inhibiting activity of 5alpha-reductase and application of traditional Chinese medicine composition to hair loss prevention cosmetics
  • Traditional Chinese medicine composition capable of inhibiting activity of 5alpha-reductase and application of traditional Chinese medicine composition to hair loss prevention cosmetics

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Effect test

Embodiment 1

[0016] The preparation of embodiment 1 Chinese medicine composition (I) and its extract

[0017] Take 100g each of Cuscuta cuscutae, scutellaria chinensis, shegan, leek seeds, scrophulariaceae, scutellaria baicalensis, broad bean root, and Artemisia capillary, grind them, pass through a 40-mesh sieve, mix them evenly, add 6.4kg of ethanol aqueous solution with a mass fraction of 50%, and heat Reflux extraction for 60 min, repeat the extraction 3 times, combine the extracts, decolorize with activated carbon, filter, and concentrate the filtrate under reduced pressure to extract.

Embodiment 2

[0018] The preparation of embodiment 2 Chinese medicine composition (II) and its extract

[0019] Take 150g of dodder seed, 150g of sieve, 40g of shegan, 60g of leek seed, 70g of scrophulariaceae, 50g of baicalensis, 80g of broad bean root, and 100g of capillary wormwood. 7kg of ethanol aqueous solution, heat and reflux for extraction for 90min, repeat the extraction twice, combine the extracts, decolorize with activated carbon, filter, and concentrate the filtrate under reduced pressure to extract.

Embodiment 3

[0020] The preparation of embodiment 3 Chinese medicine composition (Ⅲ) and extract thereof

[0021] Take 100g of Cuscutae, 120g of Weltus chinensis, 70g of Shegan, 100g of Chive Seed, 50g of Scrophulariae, 80g of Scutellaria Baicalensis, 100g of Broad Bean Root, 80g of Artemisia Capillaris, grind them, pass through a 40-mesh sieve, mix evenly, and add 70% of the mass fraction 7kg of ethanol aqueous solution, heat and reflux for extraction for 70min, repeat the extraction 3 times, combine the extracts, decolorize with activated carbon, filter, and concentrate the filtrate under reduced pressure until it is in the form of an extract.

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Abstract

The invention discloses a traditional Chinese medicine composition capable of inhibiting the activity of 5alpha-reductase and an application of the traditional Chinese medicine composition to hair loss prevention cosmetics. The traditional Chinese medicine composition consists of cuscuta chinensis, herba siegesbeckiae, blackberry lily, semen allii tuberose, radix scrophulariae, scutellaria baicalensis, subprostrate sophora root and artemisia capillaries. Extracts of the traditional Chinese medicine composition can inhibit the activity of the 5alpha-reductase so that the synthesis of androgen of DHT (double hydrogen testosterone) is inhabited, the excellent function of preventing the sebrrheic alopecia is realized, and the traditional Chinese medicine composition can be used for preparing the hair loss prevention cosmetics.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine composition. The extract of the composition can inhibit the activity of 5α-reductase, has the functions of preventing hair loss and hair growth, and can be applied to anti-hair loss cosmetics. Background technique [0002] Alopecia refers to the phenomenon of hair falling out from the skin, mostly refers to the loss of hair. With the increasing work pressure of modern people, hair loss has become a major social problem faced by many people. [0003] Alopecia is mainly divided into two types: physiological alopecia and seborrheic alopecia. Physiological hair loss is often due to the atrophy and thinning of the muscle layer of the scalp tissue, which makes the blood flow of the microfilament vascular network decrease and slow down, which will become more obvious with age. The hair loss that some young people appear is often the early physiological degenerative type, mainly due to the abno...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q7/00
Inventor 龚盛昭
Owner 龚盛昭
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