Medicine for treating post-traumatic intracranial-hypotension syndrome

A low intracranial pressure syndrome and post-traumatic technology, applied in the directions of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the initiating factors of excessive absorption of arachnoid particles, intracranial pressure that cannot improve choroidal vasomotor dysfunction. It is not easy to improve and control the effect and other problems, and achieve the effect of alleviating intracranial venous dilatation, reducing the type and dosage of drugs, and increasing the burden on the liver and kidney.

Inactive Publication Date: 2014-03-05
王建国
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Simply stimulating cerebrospinal fluid secretion to increase intracranial pressure does not improve the initiating factors of choroidal vasomotor dysfunction and arachnoid granule overabsorption after trauma
This kind of treatment is often not easy to control the effect. If it is not enough, even if the secretion of cerebrospinal fluid increases, it will not be improved due to the disorder of choroidal vasomotor function and excessive absorption of arachnoid granules, so the intracranial pressure will not be improved, or it will fall again after a temporary rise; Excessive stimulation is also easy to overcompensate and cause secondary increase in intracranial pressure

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1, the weight ratio of raw materials: 10g of Pinewood, 8g of the upper leaves of the fruit, 8g of Alicanthus, 6g of Usnea, 6g of Phalaenopsis, 8g of Cuscuta, 6g of Tractoria vine, 8g of Angelica, and 3g of Pineapple.

Embodiment 2

[0027] Example 2, the weight ratio of raw materials: 20g of Pinewood, 15g of the upper leaves of the fruit, 15g of Usnea 15g, 10g of Usnea, 10g of Phalaenopsis, 15g of Cuscuta, 10g of Tractoria vine, 15g of Angelica sinensis, and 6g of Usnea chinensis.

Embodiment 3

[0028] Example 3, the weight ratio of raw materials: 15g of flat wood, 10g of the upper leaves of the fruit, 10g of Alicanthus, 8g of Usnea, 8g of Phalaenopsis, 10g of Cuscuta, 8g of Tractoria vine, 10g of Angelica sinensis, and 5g of Pineapple.

[0029] When in use, add water to decoct the traditional Chinese medicines of the present invention, including Pingdimu, Guoshangye, Aliteng, Usnea, Pteris, Cuscuta, Pterocarpus, Bianqing, and Angelica, and then combine the filtrates and take them in the morning and evening.

[0030] The effective combination and coordination of the above drugs can effectively achieve the purpose of treating post-traumatic hypotension syndrome with less side effects. The above-mentioned results are fully proved by the clinical data, and the relevant data are as follows, wherein the drug used in the study is the weight ratio of the bulk drug in Example 3.

[0031] 1 Objects and methods.

[0032] 1.1 Subject.

[0033] 1.1.1 Inclusion criteria: 30 pati...

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PUM

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Abstract

The invention discloses a medicine for treating post-traumatic intracranial-hypotension syndrome, and the medicine is used for solving the treatment problem of post-traumatic intracranial-hypotension syndrome. The medicine is characterized by being formed by processing various traditional Chinese medicines and being prepared from the following raw materials in parts by weight: 10-20 parts of ardisiae japonica, 8-15 parts of herb of denseflower bulbophyllum, 8-15 parts of herba aistolochiae, 6-10 parts of sunglo, 6-10 parts of vandenboschia auriculata, 8-15 parts of semen cuscutae, 6-10 parts of Chinese starjasmine stems, 8-15 parts of angelica sinensis and 3-6 parts of azurite ores. According to the clinical experiment, the medicine has the characteristics of good curative effect and high safety in treating the post-traumatic intracranial-hypotension syndrome, and is worthy of being popularized and applied clinically.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine for treating post-traumatic hypotension syndrome. Background technique [0002] In general, the intracranial pressure after craniocerebral injury often rises to varying degrees, and those who manifest as low intracranial pressure are rare. Occasionally, some patients had elevated intracranial pressure in the early post-injury period, and then developed intracranial hypotension. The incidence rate is about 5%, which is intracranial hypotension syndrome (IHS). This low intracranial pressure may be caused by cerebral vasospasm after injury, which affects the function of choroid plexus to secrete cerebrospinal fluid. Inhibition may also be secondary to cerebrospinal fluid leakage, shock, severe dehydration, hyponatremia, hyperventilation, and excessive cerebrospinal fluid released during surgery or lumbar puncture, etc. In addition, due to the strong leakage of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61P25/00A61P7/00
Inventor 王建国
Owner 王建国
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