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Traditional Chinese medicine composition for treating neonatal jaundice and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve problems such as drowsiness, long time for jaundice reduction, slow curative effect of patients, etc., and achieve the effect of short treatment course, high curative effect and wide source of medicine

Inactive Publication Date: 2014-04-23
南通市海门江海建设投资有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Western medicine believes that the disease is caused by jaundice due to abnormal bilirubin metabolism, and liver function tests are mainly based on unconjugated bilirubin. Conventional treatment methods include blue light irradiation, enzyme inducer phenobarbital, and nicothamide. The curative effect is certain, but it requires qualified hospitals, and the curative effect on some patients is slow, the yellowing time is long, and there are side effects such as drowsiness

Method used

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preparation example Construction

[0050] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition, when the dosage form of the Chinese medicine composition is a decoction, specifically:

[0051] Mix the components of the raw materials in proportion, add water 8 to 10 times the mass of the mixture, boil, decoct for 2 to 3 hours, filter the decoction, obtain the first filtrate, and add the filter residue 2 times the mass of the mixture again Boil ~4 times the water, decoct for 1-2 hours, filter the decoction to obtain the second filtrate, combine the first and second filtrates, centrifuge for 30 minutes to 1 hour, extract the supernatant, and concentrate When the crude drug concentration is 1g / ml~2g / ml, a decoction is obtained.

[0052] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition, when the dosage form of the Chinese medicine composition is a granule, specifically:

[0053] Mix the components of t...

Embodiment 1

[0056] Embodiment 1 Decoction

[0057] Scutellaria baicalensis 75g, three needles 25g, rhubarb 40g, golden grass 30g, verbena 35g, Yunzhi 25g, milk thistle 25g, Gongluomu 15g, gentian 25g, Beiliu Jinu 45g, Imperata 25g, white fresh 30g of skin, 25g of Lobelia, 35g of Dijincao, 25g of Chinese medicine, 40g of Lisiana, 25g of Magnolia officinalis, 45g of Astragalus, 35g of Sanleng, 50g of capillary, and 30g of jujube, add 6kg of water to boil, decoct for 3 hour, the decoction was filtered, the first filtrate obtained, the filter residue was added to 2kg of water again and boiled, decocted for 2 hours, the decoction was filtered to obtain the second filtrate, the first filtrate and the second filtrate were combined, Centrifuge for 1 hour, extract the supernatant, concentrate until the crude drug concentration is 1g / ml, and obtain a decoction.

Embodiment 2

[0058] Example 2 Granules

[0059] Scutellaria baicalensis 75g, three needles 25g, rhubarb 40g, golden grass 30g, verbena 35g, Yunzhi 25g, milk thistle 25g, Gongluomu 15g, gentian 25g, Beiliu Jinu 45g, Imperata 25g, white fresh 30g of skin, 25g of Lobelia, 35g of Dijincao, 25g of Chinese medicine, 40g of Lisiana, 25g of Magnolia officinalis, 45g of Astragalus, 35g of Sanleng, 50g of capillary, and 30g of jujube, add 6kg of water to boil, decoct for 3 hour, the decoction was filtered, the first filtrate obtained, the filter residue was added to 2kg of water again and boiled, decocted for 2 hours, the decoction was filtered to obtain the second filtrate, the first filtrate and the second filtrate were combined, Centrifuge for 1 hour, extract the supernatant, concentrate and remove the solvent to obtain a dry paste, crush it into powder, add 140g of sucrose powder, make a soft material with ethanol with an alcohol concentration of 85%, granulate with a swinging granulator, and dr...

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition for treating neonatal jaundice. The traditional Chinese medicine composition comprises the following active pharmaceutical ingredients: baical skullcap root, root of Anhwei barberry, rhubarb, snowbell-leaf tickclover herb, European verbena, trametes versicolor, milk thistle, leatherleaf mahonia, Chinese gentian, siphonostegia chinensis, lalang grass rhizome, densefruit pittany root-bark, Chinese lobelia herb, humifuse euphorbia herb, false Chinese swertia herb, longtube ground ivy herb, officinal magnolia bark, membranous milkvetch root, common burreed rhizome, virgate wormwood herb and Chinese date. Compared with treatment by a western medicine, the traditional Chinese medicine composition has the advantages of wide medicinal sources, high speed of removing the jaundice, short course of treatment, good curative effect and no side effects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating neonatal jaundice and a preparation method thereof. Background technique [0002] Neonatal jaundice, also known as neonatal hyperbilirubinemia (hereinafter referred to as hyperbilirubin), is a phenomenon of yellow staining of the skin and sclera caused by increased bilirubin in the body. It is a common clinical symptom in the neonatal period. Many and complex, but the toxic effect of hyperbilirubinemia on the nervous system has attracted more and more attention, especially premature infants, low birth weight infants, high courage, long duration, and more toxic effects on the nervous system Obviously, a small number of children may develop bilirubin encephalopathy, leading to neurological damage and functional disability, causing great harm to society and families. [0003] Neonatal jaundice is divided i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K36/902A61P1/16
Inventor 韩英华王林曹爱芳孔建
Owner 南通市海门江海建设投资有限公司
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