Design of comprehensive extraction process for barberry plant resources

A technology of comprehensive extraction and process design, applied in the direction of drug combination, plant raw materials, plant/algae/fungus/moss components, etc., can solve the problems of inability to eliminate diarrhea, abdominal pain, aggravated diarrhea, abdominal pain, etc.

Inactive Publication Date: 2013-04-24
李玉山
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In addition, frequent use of berberine is prone to drug resistance, which not only cannot eliminate diarrhea and abdominal pain, but may even aggravate diarrhea and abdominal pain, as well as bring about other adverse rea

Method used

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  • Design of comprehensive extraction process for barberry plant resources
  • Design of comprehensive extraction process for barberry plant resources
  • Design of comprehensive extraction process for barberry plant resources

Examples

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Embodiment Construction

[0030]Put three needle coarse powders into the percolation tank, pump the prepared solvent into the percolation tank, and start percolation. During the percolation process, adjust the percolation flow rate (100-150 Liters per minute), until the pH value of the exuded medicinal solution is checked with pH test paper to be 3 and no longer changes, which proves that the medicinal solution percolates completely and stops the percolation. Fix the cleaned ceramic filter to the end of the percolate outflow pipe, filter the percolate into the seepage collection tank, and pump the seepage into the neutralization tank when the seepage reaches half of the collection tank inside the tank. Flush the dregs of the medicine dregs that have been percolated and drained in the extraction tank into the dregs collection tank with water, clean up the extraction tank, and use it for the next batch of percolation. The three needles extract was adjusted to pH 5-6 with liquid caustic soda, stirred, al...

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Abstract

The invention discloses a design of a comprehensive extraction process for barberry plant resources. Berbamine hydrochloride, jatrorrhizine hydrochloride, palmatine hydrochloride and a muscle relaxant are synchronously, efficiently and comprehensively extracted while berberine hydrochloride is extracted, and berbamine is used as a raw material for synthesizing an analgesic drug. Therefore, the barberry plant resources are fully utilized, the added medicinal value is increased, and the comprehensive utilization rate of medicinal barberry is increased. For a traditional Chinese medicine, one medicinal part is often utilized only and other parts are discarded. Various components in the barberry are synchronously extracted and comprehensively utilized, so that the economic value of the barberry is greatly increased.

Description

technical field [0001] The invention relates to a comprehensive extraction process design of three-needle plant resources. Background technique [0002] The three needles are the roots of Berberis soulieana Schneid, B. Wilson-ae Hemsl. B. Poiretii Schneid. or B. Vernae Schneid. It mainly contains berberine (berberine), palmatine (palmatine), berbamine (berbamine), jatrorrhizine (jatrorrhizine), and also contains African tetrandrine (columbamine), spiked Alkali (oxyacanthine), isotetrandine, magnoflorine, etc. Berberine hydrochloride is also called berberine hydrochloride, berberine hydrochloride, berberine hydrochloride. English name: Berberine Hydrochloride, molecular formula C 20 h 18 ClNO 4 , is an isoquinoline alkaloid, present in many plants of 4 families and 10 genera such as Berberidaceae, easily soluble in water, insoluble in benzene, ether and chloroform. Berberine is a quaternary ammonium alkaloid, and the solubility of its salts in water is relatively small,...

Claims

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Application Information

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IPC IPC(8): C07D455/03C07D491/18A61K36/29A61P21/02A61P29/00
Inventor 李玉山
Owner 李玉山
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