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Chinese medicinal composition for treating arthritis and preparation method thereof

A technology for osteoarthritis and composition, which is applied in the field of traditional Chinese medicine, can solve the problems of high risk, non-targeted treatment function of Chinese patent medicine, high cost, etc., achieve remarkable curative effect, strengthen the function of promoting blood circulation and removing blood stasis, and be easy to take.

Active Publication Date: 2014-04-23
HUNAN UNIV OF CHINESE MEDICINE +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention aims to overcome the disadvantages of western medicine, such as large side effects, high cost and high risk, and the existing Chinese patent medicines are not targeted at the functions, the preparation technology is not advanced, and there is no modern research for clinical verification, etc., and provides a clinical curative effect Exact traditional Chinese medicine composition for treating osteoarthritis and preparation method thereof

Method used

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  • Chinese medicinal composition for treating arthritis and preparation method thereof
  • Chinese medicinal composition for treating arthritis and preparation method thereof
  • Chinese medicinal composition for treating arthritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1: Preparation of Granules

[0030] Epimedium 15g, Drynaria 15g, Astragalus 25g, Angelica 5g, Salvia miltiorrhiza 15g, Wujiapi 15g, Snakevine 25g, Paeoniae Alba 25g, Citrus aurantium 10g, Licorice 3g

[0031] Weigh the original medicinal materials according to the above amount, (1) Angelica and Fructus Citrus Fructus are steam distilled for 5 hours, and the distillate A is collected for use; the distilled aqueous solution B and dregs C are collected separately for use; (2) Salvia miltiorrhiza and Snake Rattan is extracted twice with 80% ethanol under reflux. The amount of ethanol solution is 8 times and 6 times that of the raw material, and the extraction time is 2 hours and 1.5 hours respectively. The alcohol extraction solution D and the alcohol extraction residue E are collected. Standby; (3) Epimedium, Rhizoma Drynariae, Radix Astragali, Cortex Wujiapi, Radix Paeoniae Alba, Radix Glycyrrhizae, Dregs C, Dregs E were extracted twice with water as the solvent, ...

Embodiment 2

[0032] Embodiment 2: the preparation of capsule

[0033]Epimedium 20g, Drynaria 20g, Astragalus 30g, Angelica 5g, Salvia miltiorrhiza 15g, Wujiapi 15g, Snakevine 30g, Paeoniae Alba 30g, Citrus aurantium 10g, Licorice 5g

[0034] Weigh the original medicinal materials according to the above amount, (1) Angelica and Fructus Citrus Fructus are steam distilled for 6 hours, and the distillate A is collected for later use; the distilled aqueous solution B and dregs C are collected separately for later use; (2) Salvia miltiorrhiza and southern snake Rattan is extracted twice with 85% ethanol under reflux. The amount of ethanol solution is 8 times and 6 times that of the raw material, and the extraction time is 2 hours and 1.5 hours respectively. The alcohol extraction solution D and the alcohol extraction residue E are collected. Standby; (3) Epimedium, Rhizoma Drynariae, Radix Astragali, Cortex Wujiapi, Radix Paeoniae Alba, Radix Glycyrrhizae, Dregs C, Dregs E were reflux extracted ...

Embodiment 3

[0035] Embodiment 3: the preparation of tablet

[0036] Epimedium 10g, Drynaria 10g, Astragalus 15g, Angelica 5g, Salvia miltiorrhiza 10g, Wujiapi 10g, Snakevine 15g, Paeoniae Alba 15g, Citrus aurantium 10g, Licorice 5g

[0037] Weigh the original medicinal materials according to the above amount, (1) Angelica and Fructus Citrus Fructus are steam distilled for 5 hours, and the distillate A is collected for use; the distilled aqueous solution B and dregs C are collected separately for use; (2) Salvia miltiorrhiza and Snake Rattan is extracted twice with 90% ethanol under reflux. The amount of ethanol solution is 8 times and 6 times that of the raw material, and the extraction time is 2 hours and 1.5 hours respectively. The alcohol extraction solution D and the alcohol extraction residue E are collected. Standby; (3) Epimedium, Rhizoma Drynariae, Radix Astragali, Cortex Wujiapi, Radix Paeoniae Alba, Radix Glycyrrhizae, Dregs C, Dregs E were reflux extracted twice with water as t...

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Abstract

The invention discloses a Chinese medicinal composition for treating arthritis and a preparation method thereof. The Chinese medicinal composition is prepared from the following Chinese drugs in a certain weight proportion: epimedium herb, rhizoma drynariae, astragalus, Chinese angelica, red-rooted salvia root, white peony root, cortex acanthopanacis, celastrus orbiculatus, bitter orange and liquorice. Pharmacological studies and clinical researches indicate that the composition has the effects of nourishing kidney and strengthening essence, tonifying qi and blood, activating blood circulation to remove stasis, dredging collaterals and strengthening bones, dispelling wind and eliminating dampness, relieving pains and removing arthralgia and the like, can be used for treating patients with osteoarthritis or heumatism clinically, and has a wide application prospect and social and economic values.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating osteoarthritis and a preparation method thereof. Background technique [0002] Osteoarthritis (OA) is a chronic joint disease characterized by degeneration and destruction of articular cartilage and bone hyperplasia. There is no obvious racial and regional difference. It is a common and frequently-occurring disease. The disease can start from the age of 20, but most of them are asymptomatic and generally difficult to find. It occurs frequently after middle age, and its incidence rate increases with age, and it is more common in women than men. The prevalence rate of 40-year-old crowd is 10%~17%, then reaches 50% over 60 years old, and 80% suffers from this disease among the crowd over 75 years old, and the final disability rate of this disease is as high as 53%. In the United States, about 46 million Am...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61P19/02
Inventor 李顺祥高洁生严建业黄丹王元清曾佳
Owner HUNAN UNIV OF CHINESE MEDICINE
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