Diamino triazine hydrogen bond enhanced hydrogel based on cyclodextrin crosslinking and preparation method and application thereof

A technology of diaminotriazine and cyclodextrin, applied in the field of hydrogel, can solve the problems of limited application and poor mechanical properties, and achieve the effects of improving mechanical properties, high water absorption, easy long-term storage and long-distance transportation
CN103172802BInactive Publication Date: 2015-07-08TIANJIN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
TIANJIN UNIV
Publication Date
2015-07-08
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a diamino triazine hydrogen bond enhanced hydrogel based on cyclodextrin crosslinking and a preparation method and an application thereof. The diamino triazine hydrogen bond enhanced hydrogel based on cyclodextrin crosslinking is prepared from 2-vinyl-4,6-diamino-1,3,5-triazine and beta-cyclodextrin with double bond through free radical polymerization and copolymerization; the two monomers and an initiator are dissolved in a solvent; unsaturated bonds on the molecules thereof are initiated by the initiator; and the hydrogel is prepared through a free radical polymerization reaction. The hydrogel disclosed by the invention has high stretch resistance and compression resistance and good biocompatibility.
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Description

technical field

[0001] The present invention relates to the field of hydrogels, more specifically, to high-strength hydrogels with dual functions of drug and gene release and its preparation method, namely β-cyclodextrin and 2-vinyl-4,6-diamino - Preparation of 1,3,5-triazine copolymer (PCD-co-PVDT) hydrogel and its performance as a drug carrier and gene carrier. Background technique

[0002] Hydrogel is a kind of polymer with a three-dimensional network structure that uses water as the dispersion medium, can absorb a large amount of water in water and can maintain its original structure without being dissolved. At the same time, it also has good water permeability and biocompatibility, and can be used as a human implant to reduce adverse reactions. Therefore, hydrogels are widely used as excellent biomedical materials. However, for conventional hydrogels, poor mechanical properties limit their applications as biomaterials, especially mechanical devices. In recent years, ...

Claims

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