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Method for preparing drug for treating multiple epiphyseal dysplasia

A dysplasia and multiplex technology, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, can solve the problems of inability to obtain curative effects, achieve good compliance, reduce drug types and dosage, and prepare methods unique effect

Inactive Publication Date: 2013-07-10
徐涛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the treatment of this disease with "consolidating the root and nourishing the essence, nourishing the liver and kidney" is bound to fail to obtain good curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1, the weight ratio of raw materials: 10 parts of litchi core, 6 parts of kapok bark, 3 parts of poria cocos, 6 parts of tangerine peel, 3 parts of Gingengcao, 6 parts of terrazzo, 6 parts of kudzu root, 6 parts of aescin, 6 parts of loofah, 1 part of Jiulixiang, 3 parts of burnt malt, and 10 parts of burnt grain sprouts.

Embodiment 2

[0035] Example 2, raw material drug weight ratio: 20 parts of litchi core, 10 parts of kapok bark, 6 parts of poria cocos, 10 parts of tangerine peel, 6 parts of stalks, 10 parts of terrazzo, 10 parts of kudzu root, 10 parts of aescin, 10 parts of loofah, 2 parts of Jiulixiang, 6 parts of burnt malt, 20 parts of burnt grain sprouts.

Embodiment 3

[0036] Embodiment 3, raw material drug weight ratio: 30 parts of litchi cores, 12 parts of kapok bark, 10 parts of poria cocos, 12 parts of dried tangerine peel, 10 parts of stalks, 12 parts of terrazzo, 12 parts of kudzu root, 12 parts of aescin, 12 parts of loofah, 5 parts of Jiulixiang, 10 parts of burnt malt, and 25 parts of burnt grain sprouts.

[0037] The Chinese medicine of embodiment 1~3 can be prepared by the following method:

[0038] (1) Extract the volatile oils from kudzu root, kapok bark, and cassia stalks by steam distillation, and collect them and mix them for later use;

[0039] (2) Grind burnt grain buds and burnt malt through a 150-mesh sieve to form fine powder for later use;

[0040] (3) Mix lychee core, poria cocos, tangerine peel, twig vine, loofah, aescin, jiulixiang, add 10 times the amount of water, add water and decoct twice, 1 hour each time, combine the decoction, and let it stand; then Add 3~4 times of 95% ethanol to the decoction, let it stand f...

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PUM

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Abstract

The invention discloses a method for preparing a drug for treating multiple epiphyseal dysplasia. The drug is applied to the treatment of multiple epiphyseal dysplasia. The drug is characterized by being prepared from the following raw pharmaceutical materials in proportioning ratio by weight: litchi chinensis Sonn., bombax malabaricum peel, poriacocos (Schw.) Wolf, citrus reticulata Blanco, aeschynomene indica L., trachelospermum jasminoides (Lindl.) Lem., radix puerariae, paris polyphylla Sm., luffa cylindrica (L.) Roem., murraya jasminorage, hordeum vulgare L. and setaria italica (L.) Beauv.. The method comprises the following steps of: (1) extracting volatile oil from coarse powder of radix puerariae, bombax malabaricum peel and aeschynomene indica L. for later use; (2) crushing setaria italica (L.) Beauv. into fine powder for later use; (3) carrying out water extraction and alcohol precipitation on litchi chinensis Sonn., poriacocos (Schw.) Wolf, citrus reticulata Blanco, trachelospermum jasminoides (Lindl.) Lem., luffa cylindrica (L.) Roem., paris polyphylla Sm., murraya jasminorage and hordeum vulgare L., and drying so as to obtain a preliminary material; and (4) spraying the volatile oil into the preliminary material, adding the fine powder of setaria italica (L.) Beauv., uniformly mixing, sieving by using a 60-mesh sieve, and encapsulating. Proved by clinical trials, the drug prepared by the method has the characteristics of good treatment effect and high safety in the treatment of multiple epiphyseal dysplasia, so that the method is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a preparation method of a medicine for treating multiple epiphyseal dysplasia. Background technique [0002] Muffiple epiphyseal dysplaais (MED) is an inherited cartilage developmental defect characterized by abnormal ossification of many epiphyses, growth disturbances, and stubby fingers. The main clinical manifestations are pain in the hip and knee joints, limited mobility, difficulty in walking, and a swinging gait. Shoulder joint mobility is also limited. The bone ends are often thick, and a few patients have joint flexion deformity or joint laxity. Shorter hands, thicker fingers, shorter stature. Because the disease affects the long bones of the extremities more significantly than the spine, it manifests as a short-limbed dwarf to some extent. In addition, there are genu varus, valgus, unequal length of the two lower limbs, and kyphosis. The applicant's resea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61K9/48A61P19/08
Inventor 徐涛
Owner 徐涛
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