Content detection method for Naoxintong capsule

A detection method, a brain-to-heart technology, applied to measuring devices, instruments, scientific instruments, etc., can solve the problem of large dosage, achieve strong specificity, increase dissolution speed, and improve separation effect
CN103207255AActive Publication Date: 2013-07-17SHAANXI BUCHANG PHARMA

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHAANXI BUCHANG PHARMA
Publication Date
2013-07-17

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Abstract

The invention relates to a content detection method for the Naoxintong capsule. The Naoxintong capsule comprises 66 parts of astragalus root, 27 parts of red peony root, 27 parts of root of red-rooted salvia, 27 parts of Chinese angelica, 27 parts of Szechuan lovage rhizome, 27 parts of peach kernel, 13 parts of safflower, 13 parts of prepared Frankincense, 13 parts of prepared myrrh, 20 parts of suberect spatholobus stem, 27 parts of twotooth achyranthes root, 20 parts of cassia twig, 27 parts of mulberry twig, 27 parts of earthworm, 13 parts of scorpion, and 27 parts of leech. The main chemical components, namely hydroxy safflower yellow A, paeoniflorin, ferulic acid, salvianolic acid B and ligustilide, in the Naoxintong capsule are simultaneously measured by the UPLC (ultra-performance liquid chromatography) technique. Single chromatographic analysis can be completed in 24 minutes. Chromatographic peaks of the main components are well separate, RSD (relative standard deviation) in both precision and receptiveness is smaller than 2.0%, and the quality of Naoxintong capsule can be controlled comprehensively.
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Description

technical field

[0001] The invention relates to a method for detecting the content of Naoxintong capsules, which belongs to the technical field of pharmaceutical preparations. Background technique

[0002] Naoxintong Capsules (commercially available product, the quality standard was disclosed in the "Internal Medicine - Brain System" sub-volume of "National Standards Compilation of Chinese Proprietary Drugs - National Standards of Chinese Proprietary Medicines Rising Local Standards" compiled by the State Drug Administration in 2002, standard No.: WS-10001 (ZD-0001)-2002) is composed of astragalus, red peony root, salvia miltiorrhiza, angelica, chuanxiong, safflower, peach kernel, frankincense (made), myrrh (made), spatholobus, achyranthes bidentata, osmanthus It is a clinically commonly used compound preparation of traditional Chinese medicine made from 16 medicinal materials such as twig, mulberry branch, earthworm, scorpion, and leech. Treatment of middle meridian and ch...

Claims

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