Yinhuang granule for clearing away the lung-heat and preparation method thereof

A technology of Yinhuang clearing the lungs and granules, which is applied in the direction of medical formulas, medical preparations containing active ingredients, etc., and can solve the problems of spilled capsule contents, inaccurate doses, and unsatisfactory effects, etc. problems, to achieve the effect of convenient brewing and adjustment, excellent therapeutic effect and excellent clinical effect

Active Publication Date: 2013-09-04
湖南安邦制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, when dealing with children, due to the large size of the capsules, in order to facilitate swallowing, children generally break the capsules and pour out the contents when taking medicine, which may easily cause the contents of the capsules to spill during the opening process. , but also lead to inaccurate dosage, and the taste of the capsule contents is bitter, which makes it difficult for children to take it
[0004] In addition, the current commercially available drugs have unsatisfactory effects on relieving cough, resolving phlegm, and calming asthma, which prolongs the cure period of chronic bronchitis. In addition to the storm of "poisonous capsules" recently, there is an urgent need for an easy-to-take and effective drug replacement product

Method used

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  • Yinhuang granule for clearing away the lung-heat and preparation method thereof
  • Yinhuang granule for clearing away the lung-heat and preparation method thereof
  • Yinhuang granule for clearing away the lung-heat and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] 1) The raw materials are as follows: Tinglizi 60g; Ephedra 37.5g; Bitter almond 45g; Fritillaria 45g; Loquat leaves 45g; ; Citrus aurantium 15g; Gypsum 60g; Licorice 15g.

[0036] 2) Weigh the above-mentioned fourteen traditional Chinese medicines according to the formula, and crush the ephedra into ephedra powder with a particle size of 125 μm, and set aside. Put citrus citrus citrus fruit, loquat leaves and calamus into the first extraction tank, add 5 times the amount of water, and co-distill for 6 hours to obtain volatile oil, extract and extract residue; use β-cyclodextrin at 40 ° C The volatile oil was clathrated for 2 hours, and dried at 60°C for 2 hours to obtain the clathrate.

[0037] 3) Put Tinglizi, bitter almonds, Fritillaria fritillaria and Schisandra chinensis into the second extraction tank at room temperature, add 5 times the amount of ethanol with a mass concentration of 70% to the second extraction tank, and repeat the impregnation at room temperatur...

Embodiment 2

[0041] 1) The raw materials are as follows: Tinglizi 55g; Sun-roasted ephedra 40g; Bitter almond 40g; Fritillaria 50g; Loquat leaves 50g; Daqingye 32g; ; Citrus aurantium 18g; Gypsum 55g; Licorice 12g.

[0042] 2) Weigh the above-mentioned fourteen traditional Chinese medicines according to the formula, and grind the ephedra ephedra into a ephedra ephedra powder with a particle size of 128 μm for later use. Put citrus citrus citrus fruit, loquat leaves and calamus into the first extraction tank, add 7 times the amount of water, and distill for 3 hours to obtain volatile oil, extract and extract residue; use β-cyclodextrin at 30 ° C The volatile oil was clathrated for 4 hours and dried at low temperature for 6 hours to obtain clathrates.

[0043] 3) Put Tinglizi, bitter almonds, fritillary fritillary and Schisandra chinensis into the second extraction tank at room temperature, add 8 times the amount of ethanol with a mass concentration of 60% to the second extraction tank, and...

Embodiment 3

[0047] 1) The raw materials are as follows: Tinglizi 65g; Ephedra 35g; Bitter almond 50g; Fritillaria 40g; Loquat leaves 40g; Citrus aurantium 12g; raw gypsum 65g; licorice 18g.

[0048] 2) Weigh the above-mentioned fourteen traditional Chinese medicines according to the formula, and crush the ephedra into ephedra powder with a particle size of 130 μm, and set aside. Put citrus aurantium, loquat leaves and calamus into the first extraction tank, add 6 times the amount of water, and co-distill for 5 hours to obtain volatile oil, extract and extract residue; use β-cyclodextrin at 50 ° C to extract The volatile oil was clathrated for 4 hours, and dried at low temperature for 4 hours to obtain the clathrate.

[0049] 3) Put Tinglizi, bitter almonds, Fritillaria fritillaria and Schisandra chinensis into the second extraction tank at room temperature, add 6 times the amount of ethanol with a mass concentration of 70% to the second extraction tank, and repeat the impregnation at roo...

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Abstract

The invention discloses a Yinhuang granule for clearing away the lung-heat and a preparation method thereof. The Yinhuang granule comprises raw materials in parts by weight as follows: 55-65 parts of semen lepidii, 35-40 parts of ephedra or fried ephedra, 40-50 parts of semen armeniacae amarae, 40-50 parts of fritillary bulb, 40-50 parts of folium eriobotryae, 27-32 parts of folium isatidis, 40-50 parts of rhizoma acori graminei, 40-50 parts of dioscorea nipponica makino, 27-32 parts of artemisia rupestris, 40-50 parts of ginkgo leaves, 12-18 parts of schisandra chinensis, 12-18 parts of immature bitter orange, 55-65 parts of gypsum and 12-18 parts of liquorice. Active ingredient content of volatile oil in the prepared Yinhuang granule for clearing away the lung-heat is high, particularly the Yinhuang granule for clearing away the lung-heat has the better curative effect on aspects of clearing lung, eliminating phlegm, clearing lung and eliminating phlegm and the like, and the clinical effect can be played optimally.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to Yinhuang Qingfei Granules and a preparation method thereof. Background technique [0002] Chronic bronchitis is a clinically common and frequently-occurring disease, which can be caused by influenza and belongs to the category of cough in traditional Chinese medicine. Winter and spring are the peak seasons of its attack every year. The disease involves a wide range of regions and a large population base, but there is no obvious regional difference in the incidence rate in various regions, and it is more common in children, middle-aged and elderly people. According to statistics, chronic bronchitis has a relatively high incidence rate in the normal population, with an overall incidence rate of 3.0% to 6.6%, among which the incidence rate in people over 50 years old is 14.2% to 18.0%, and the incidence rate in children is 3%. The acute exacerbation of chron...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61K47/48A61K9/16A61P11/00A61P11/10A61P11/14A61P11/06C11B9/02A61K36/73A61K36/752A61K36/888A61K33/06
Inventor 高尚
Owner 湖南安邦制药股份有限公司
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