Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Extract of aerial parts of maca rich in polyphenols and composition comprising same

A technology of aerial parts and extracts, which is used in drug combinations, medical preparations containing active ingredients, functions of food ingredients, etc.

Inactive Publication Date: 2013-09-04
LAB EXPANSCIENCE
View PDF31 Cites 13 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, none of these indications have been materialized by scientific research
[0021] Furthermore, the aerial parts of Maca are generally considered waste and thus never used or upcycled for cosmetic, dermatological, pharmaceutical or nutraceutical purposes

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Extract of aerial parts of maca rich in polyphenols and composition comprising same
  • Extract of aerial parts of maca rich in polyphenols and composition comprising same
  • Extract of aerial parts of maca rich in polyphenols and composition comprising same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0121] 5% dried and ground macadamia leaf stems were suspended in a 10 / 90 w / w ethanol / water mixture for 1 hour at ambient temperature with stirring. Residual dry matter is separated from the liquid phase by filtration, settling or centrifugation, and the obtained liquid phase can be filtered using a filter of suitable porosity to obtain a clear solution. The obtained extract has the following characteristics:

[0122] - Dried extract: 1.8%

[0123] -Total sugar (HPLC): 32% / dry matter

[0124] -Total polyphenols (Folin-Ciocalteu): 5.7% / dry matter

[0125] - Total flavonoids (AlCl3): 1.7%

[0126] The extract has "in tubo" anti-radical, anti-DPPH activity, where the half maximal inhibitory concentration (IC50) was determined and which is 0.29 mg of dry extract representing 20 μg of polyphenols in the reaction medium.

Embodiment 2

[0128] 5% dried and ground macadamia leaf stems were suspended in a 50 / 50 w / w glycerol / water mixture with stirring for 1 hour at ambient temperature. Residual dry matter is separated from the liquid phase by filtration, settling or centrifugation, and the obtained liquid phase can be filtered using a filter of suitable porosity to obtain a clear solution. The obtained extract has the following characteristics:

[0129] - Dried extract: 1.8%

[0130] -Total sugar (HPLC): 37% / dry matter

[0131] -Total polyphenols (Folin-Ciocalteu): 6.4% / dry matter

[0132] - Total flavonoids (AlCl3): 2.2%

[0133] The extract has "in tubo" anti-radical, anti-DPPH activity, where the half maximal inhibitory concentration (IC50) was determined and which is 0.26 mg of dry extract representing 16.5 μg of polyphenols in the reaction medium.

Embodiment 3

[0135] 5% dried and ground macadamia leaf stems were suspended in 80 / 20 w / w propylene glycol / water mixture for 1 hour at ambient temperature with stirring. Residual dry matter is separated from the liquid phase by filtration, settling or centrifugation, and the obtained liquid phase can be filtered using a filter of suitable porosity to obtain a clear solution. The obtained extract has the following characteristics:

[0136] - Dried extract: 1.1%

[0137] -Total sugar (HPLC): 40% / dry matter

[0138] -Total polyphenols (Folin-Ciocalteu): 7.6% / dry matter

[0139] - Total flavonoids (AlCl3): 3.6%

[0140] The extract has "in tubo" anti-radical, anti-DPPH activity, where the half maximal inhibitory concentration (IC50) was determined and which is 0.28 mg of dry extract representing 22.5 μg of polyphenols in the reaction medium.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
sizeaaaaaaaaaa
Login to View More

Abstract

The invention relates to an extract of aerial parts of Maca rich in polyphenols, and also to a composition comprising such an extract and, where appropriate, a suitable excipient. The invention also relates to a process for extracting an extract of aerial parts of Maca rich in polyphenols, and also to the extract that can be obtained by means of said process. The invention also relates to such a composition or such an extract for use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the superficial body growths and / or for use thereof in preventing and / or treating vascular disorders. Finally, the invention relates to a cosmetic care process for the skin, the superficial body growths or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which comprises the administration of such a composition or of such an extract.

Description

technical field [0001] The present invention relates to extracts of aerial parts of Maca (Lepidium meyenii) rich in polyphenols (and more particularly rich in flavonoids), advantageously extracts of Maca leaves, and extracts comprising said extracts. composition of matter. Advantageously, said composition is a cosmetic, pharmaceutical, dermatological or nutraceutical composition. [0002] The invention also relates to a process for the extraction of an extract of aerial parts of maca rich in polyphenols, and more particularly in flavonoids, and also to an extract suitable for obtaining by said process. [0003] The invention also relates to the use of said composition or said extract for the prophylaxis or treatment of diseases or pathological conditions of the skin, mucous membranes or skin appendages, for the prevention or treatment of vascular diseases, inflammatory reactions or pathological conditions Use for preventing or treating adipose tissue regulation or for preven...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/31A23L1/30A61K8/97A61Q19/00A61P17/00A61P9/00A23L33/00
CPCA61K8/368A61K8/498A61Q19/08A61K2800/805A23L33/105A61K36/31A61K8/9789A61P17/00A61P9/00A61K31/352A23V2002/00A23V2200/318A61K2236/33A61K31/05A61K31/198A61K31/201A61K31/341A61K31/42A61K31/57A61K31/585A61K31/717A61K33/30A61K36/28A61K36/48A61K36/54A61K36/899A61K38/00A61K45/00A61K31/197A61K31/715
Inventor A·索努瓦C·鲍德温S·勒克莱尔-比安费S·加尼耶P·姆西卡
Owner LAB EXPANSCIENCE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com