Traditional Chinese medicine preparation for treating hemophilia and preparation method thereof

A traditional Chinese medicine preparation and technology for hemophilia, applied in the field of pharmacy, to achieve the effects of low cost of medication, easy availability of raw materials, and definite hemostatic and pain relief effects

Inactive Publication Date: 2015-04-22
全清清
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disease is mainly a hereditary disease, and there is no radical treatment in Western medicine at present, and the basic treatment is alternative therapy, and other drugs have temporary hemostatic effect

Method used

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  • Traditional Chinese medicine preparation for treating hemophilia and preparation method thereof

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preparation example Construction

[0060] When the dosage form of described Chinese medicine preparation is syrup, its preparation method comprises the following steps:

[0061] The first step is to mix water chestnuts, madder, buffalo horn, chickweed, agrimony, violet root, mountain bean root, mountain maple, crushed dense flower and licorice according to the stated ratio, with 4 relative to the obtained mixture mass ~8 times of alcohol concentration of 75%~85% is dissolved in ethanol, heated and refluxed for 4~6 hours and then extracted, filtered to obtain the first filtrate; the filter residue is used again with 3~5 times of alcohol concentration relative to the obtained mixture quality 80%~90% of ethanol is dissolved, heated and refluxed for 2~4 hours and then extracted and filtered to obtain the second filtrate; the first filtrate and the second filtrate are combined, the ethanol is recovered under reduced pressure and concentrated to a concentration of 0.6~ 0.8g crude drug / mL, eluted with a macroporous ad...

Embodiment 1

[0071] Example 1 Syrup of the present invention

[0072] Take water chestnuts 140g, madder 260g, buffalo horn 140g, astragalus 190g, chickweed 270g, Codonopsis 230g, Agrimony 260g, Viola 220g, Mountain Bean Root 80g, Mountain Maple 210g, Rehmannia glutinosa 240g, Vanilla 190g, white 190g of cogongrass, 140g of cat's claw, 230g of Ziheche, 260g of antelope horn, 280g of Artemisia annua, 200g of lotus root, 210g of white and white, 320g of broken dense flowers and 360g of licorice;

[0073] Its preparation method comprises the following steps:

[0074] The first step is to mix water chestnuts, madder, buffalo horn, chickweed, agrimony, violet root, mountain bean root, mountain maple, crushed dense flower and licorice in proportion, with 6 times the mass of the obtained mixture. Dissolve in ethanol with an alcohol concentration of 80%, extract after heating under reflux for 5 hours, and filter to obtain the first filtrate; dissolving the filter residue with ethanol with an alcoh...

Embodiment 2

[0078] Example 2 Oral liquid preparation of the present invention

[0079] Take water chestnuts 120g, madder 240g, buffalo horn 170g, astragalus 130g, chickweed 290g, Codonopsis 210g, Agrimony 220g, Radix Radix et Rhizoma 270g, Mountain Bean Root 90g, Mountain Maple 230g, Rehmannia glutinosa 210g, Vanilla 160g, white 200g of cogongrass, 120g of cat's claw, 250g of Ziheche, 210g of antelope horn, 220g of Artemisia annua, 160g of lotus root, 240g of white and 240g of white and dense flowers, 270g of broken dense flowers and 310g of licorice;

[0080] Its preparation method comprises the following steps:

[0081] The first step is to mix water chestnuts, madder, buffalo horn, chickweed, Agrimony, mountain bean root, mountain sweetgrass, Imperata antelope horn and crushed dense flowers in proportion, and use methanol with an alcohol concentration of 85% as the first step. The solvent was slowly permeated at a rate of 2ml per minute by percolation method, the percolation liquid wa...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating hemophilia and a preparation method thereof. The traditional Chinese medicine is prepared from the following crude drugs of water chestnut, radix rubiae, buffalo horn, astragalus membranaceus, chickweed, codonopsis pilosula, hairyvein agrimony, herba violae, subprostrate sophora, celastrus aculeatus, dried rehamnnia root, fragrant hair grass, lalang grass rhizome, radix ranunculi ternate, placenta hominis, antelope horn, sweet wormwood, receptaculum nelumbinis, rhizoma bletillae, broken dense flowers and liquorice. The traditional Chinese medicine preparation has the beneficial effects that the traditional Chinese medicine preparation is a pure traditional Chinese medicine preparation, free of toxic and side effects, accurate in effect of bleeding pain, fast to become effective, good in treatment effect, convenient to take, available in materials, and low in drug cost, does not generate the drug dependence after being taken for a long period of time, and can help a sufferer get rid of whole blood and blood coagulation factors; the economical burden on treatment of the sufferer is reduced.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine preparation for treating hemophilia and a preparation method. Background technique [0002] Hemophilia is a group of bleeding disorders caused by hereditary coagulation factor deficiencies. Coagulation factors are a group of biologically active proteins in the human body that can cause blood coagulation and have hemostasis functions. There are thirteen main coagulation factors, which are commonly expressed in Roman numerals: I, II....XIII (that is, coagulation factors one, two, etc.). ...to thirteen). If the blood lacks a certain clotting factor, the blood does not clot easily, causing bleeding disorders. In my country, the incidence rate of hemophilia in the social population is 5-10 / 100,000, and the incidence rate of infants is about 1 / 5,000. Typical hemophilia patients often develop coagulation dysfunction since childhood, spontaneously or af...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P7/00A61P7/04A61K35/50A61K35/32
Inventor 全清清
Owner 全清清
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