Preparation method of fresh ginger total phenols bulk drug of medicine for preventing motion sicknesses

Abstract

A preparation method of a fresh ginger total phenols bulk drug of a medicine for preventing motion sicknesses comprises the following steps of: (1) drying and smashing; and (2) supercritical extraction: adding prepared fresh ginger powder into an extraction kettle of a carbon dioxide CO2 supercritical extraction device, extracting for 60-180 min under the conditions that the temperature is 40-65 DEG C, the pressure is 20-50 MPa and the CO2 flow speed is 10kg / h, and then collecting oleoresin material by using a separator I with the pressure of 10 MPa so as to obtain the fresh ginger phenols extract, namely fresh ginger total phenols. The preparation method has the advantages that the extract has no residual solvent, the selectivity is easy to control, and the extraction efficiency is high. As the CO2 is inactive, and the extraction and separation also can be completed in a relatively short time at a normal temperature or relatively low temperature, the decomposition of unsteady components is reduced. The fresh ginger total phenols medicine extracted by the method can strengthen mid-energy and harmonize stomach, eliminate phlegm and prevent emesis and is a good medicine for preventing motion sicknesses such as carsickness and seasickness.

Description

technical field [0001] The invention relates to a preparation method of a new traditional Chinese medicine, in particular to a preparation method of ginger total phenols used for preventing motion sickness such as motion sickness and seasickness. Background technique [0002] According to relevant research, the incidence rate of motion sickness is 4%, that of long-distance seasickness is 25%-30%, and that of airsickness is 10%. About 1 / 3 of the population is susceptible to motion sickness, and the symptoms of motion sickness usually develop progressively. From stomach discomfort, nausea, increased salivation, pale complexion, cold sweats, dizziness, headache, and then developed to retching, vomiting, lethargy, and apathy. Those with severe vomiting may even become dehydrated and exhausted. It occurs when people ride in cars, boats, planes, rides, or sailing, aviation, aerospace simulations or actual operations. According to the research understanding of the pathogenesis of...

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the defects of high toxicity, strong side effects and poor effect of anti-motion sickness drugs on the market today, the object of the present invention is to provide a preparation method of ginger total phenols, a medicine for preventing motion sickness, to simplify the production process and reduce production costs; improve product quality